Vasculopathy and Coagulopathy Associated with SARS-CoV-2 Infection

Hematologic parameters in patients with COVID‐19 infection

(2020) Bingwen Eugene Fan et al.   AMERICAN JOURNAL OF HEMATOLOGY

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

(2020) Joanna Kalucka et al.   CELL

Evidence for gastrointestinal infection of SARS-CoV-2

(2020) Fei Xiao et al.   GASTROENTEROLOGY

Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China

(2020) Qiurong Ruan et al.   INTENSIVE CARE MEDICINE

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China

(2020) Zunyou Wu et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection

(2020) Jianhua Xia et al.   JOURNAL OF MEDICAL VIROLOGY

Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia

(2020) Ning Tang et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

(2020) Jasper Fuk-Woo Chan et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

First Case of 2019 Novel Coronavirus in the United States

(2020) Michelle L. Holshue et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

(2020) Renhong Yan et al.   SCIENCE

Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury

(2020) Yingxia Liu et al.   Science China-Life Sciences

Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes

(2020) Wei Zhang et al.   Emerging Microbes & Infections

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

(2020) Zhe Xu et al.   Lancet Respiratory Medicine

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

(2020) Michael Letko et al.   Nature Microbiology

Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations

(2020) Yanan Cao et al.   Cell Discovery

Angiopoietin-2 as a marker of endothelial activation is a good predictor factor for intensive care unit admission of COVID-19 patients

(2020) David M. Smadja et al.   ANGIOGENESIS

Pulmonary Arterial Thrombosis in COVID-19 With Fatal Outcome: Results From a Prospective, Single-Center, Clinicopathologic Case Series

(2020) Sigurd F. Lax et al.   ANNALS OF INTERNAL MEDICINE

Autopsy Findings and Venous Thromboembolism in Patients With COVID-19

(2020) Dominic Wichmann et al.   ANNALS OF INTERNAL MEDICINE

Histopathologic Changes and SARS-CoV-2 Immunostaining in the Lung of a Patient With COVID-19

(2020) Huilan Zhang et al.   ANNALS OF INTERNAL MEDICINE

Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions

(2020) Yvan Jamilloux et al.   AUTOIMMUNITY REVIEWS

Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses

(2020) Furong Qi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Classification of the cutaneous manifestations of COVID‐19: a rapid prospective nationwide consensus study in Spain with 375 cases

(2020) C. Galván Casas et al.   BRITISH JOURNAL OF DERMATOLOGY

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

(2020) Vanessa Monteil et al.   CELL

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients

(2020) Yun Ling et al.   CHINESE MEDICAL JOURNAL

COVID-19 and Cardiovascular Disease

(2020) Kevin J. Clerkin et al.   CIRCULATION

COVID-19 and the Heart

(2020) Akbarshakh Akhmerov et al.   CIRCULATION RESEARCH

Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?

(2020) Daniel Batlle et al.   CLINICAL SCIENCE

The characteristics of 50 hospitalized COVID-19 patients with and without ARDS

(2020) Michael Dreher et al.   Deutsches Arzteblatt International

COVID-19-related myocarditis in a 21-year-old female patient

(2020) In-Cheol Kim et al.   EUROPEAN HEART JOURNAL

Acute myocarditis presenting as a reverse Tako-Tsubo syndrome in a patient with SARS-CoV-2 respiratory infection

(2020) Simone Sala et al.   EUROPEAN HEART JOURNAL

High Prevalence of Concurrent Gastrointestinal Manifestations in Patients with SARS-CoV-2: Early Experience from California

(2020) George Cholankeril et al.   GASTROENTEROLOGY

Prevalence and Characteristics of Gastrointestinal Symptoms in Patients with SARS-CoV-2 Infection in the United States: A Multicenter Cohort Study

(2020) Walker D. Redd et al.   GASTROENTEROLOGY

Is SARS-CoV-2 Also an Enteric Pathogen With Potential Fecal–Oral Transmission? A COVID-19 Virological and Clinical Review

(2020) Siyuan Ding et al.   GASTROENTEROLOGY

Recognizing COVID-19-related myocarditis: the possible pathophysiology and proposed guideline for diagnosis and management

(2020) Bhurint Siripanthong et al.   HEART RHYTHM

Post‐mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction

(2020) T. Menter et al.   HISTOPATHOLOGY

Detection of SARS-CoV-2 in Different Types of Clinical Specimens

(2020) Wenling Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical course of 2019 novel coronavirus disease (COVID-19) in individuals present during the outbreak on the Diamond Princess cruise ship

(2020) Hideaki Kato et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

The presence of SARS‐CoV‐2 RNA in the feces of COVID‐19 patients

(2020) Yifei Chen et al.   JOURNAL OF MEDICAL VIROLOGY

Phylogenetic Analysis and Structural Modeling of SARS-CoV-2 Spike Protein Reveals an Evolutionary Distinct and Proteolytically Sensitive Activation Loop

(2020) Javier A. Jaimes et al.   JOURNAL OF MOLECULAR BIOLOGY

COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up

(2020) Behnood Bikdeli et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Histologic features of long lasting chilblain‐like lesions in a pediatric COVID‐19 patient

(2020) A.G. Locatelli et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Chilblain‐like lesions during COVID‐19 epidemic: a preliminary study on 63 patients

(2020) V. Piccolo et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Vascular skin symptoms in COVID‐19: a french observational study

(2020) JD Bouaziz et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

High incidence of venous thromboembolic events in anticoagulated severe COVID‐19 patients

(2020) Jean‐François Llitjos et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

ISTH interim guidance on recognition and management of coagulopathy in COVID‐19

(2020) Jecko Thachil et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia

(2020) Songping Cui et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Electron microscopy of SARS-CoV-2: a challenging task

(2020) Cynthia S Goldsmith et al.   LANCET

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study

(2020) Lucio Verdoni et al.   LANCET

The many estimates of the COVID-19 case fatality rate

(2020) Dimple D Rajgor et al.   LANCET INFECTIOUS DISEASES

Structural basis of receptor recognition by SARS-CoV-2

(2020) Jian Shang et al.   NATURE

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

(2020) Waradon Sungnak et al.   NATURE MEDICINE

Controversies of renin–angiotensin system inhibition during the COVID-19 pandemic

(2020) Andrew M. South et al.   Nature Reviews Nephrology

Clinical characteristics and outcomes of inpatients with neurologic disease and COVID-19 in Brescia, Lombardy, Italy

(2020) Alberto Benussi et al.   NEUROLOGY

The Covid-19 Pandemic and the Incidence of Acute Myocardial Infarction

(2020) Matthew D. Solomon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Covid-19 in Critically Ill Patients in the Seattle Region — Case Series

(2020) Pavan K. Bhatraju et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reduced Rate of Hospital Admissions for ACS during Covid-19 Outbreak in Northern Italy

(2020) Ovidio De Filippo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

(2020) Muthiah Vaduganathan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1

(2020) Neeltje van Doremalen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young

(2020) Thomas J. Oxley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ocular Findings and Proportion with Conjunctival SARS-COV-2 in COVID-19 Patients

(2020) Yunyun Zhou et al.   OPHTHALMOLOGY

Abdominal Imaging Findings in COVID-19: Preliminary Observations

(2020) Rajesh Bhayana et al.   RADIOLOGY

Cytokine release syndrome in severe COVID-19

(2020) John B. Moore et al.   SCIENCE

COVID-19-Related Severe Hypercoagulability in Patients Admitted to Intensive Care Unit for Acute Respiratory Failure

(2020) Luca Spiezia et al.   THROMBOSIS AND HAEMOSTASIS

Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection

(2020) Xin Zou et al.   Frontiers of Medicine

Upsurge of deep venous thrombosis in patients affected by COVID-19: Preliminary data and possible explanations

(2020) Enrico M. Marone et al.   Journal of Vascular Surgery-Venous and Lymphatic Disorders

Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19)

(2020) Riccardo M. Inciardi et al.   JAMA Cardiology

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

(2020) Tao Guo et al.   JAMA Cardiology

Potential Effects of Coronaviruses on the Cardiovascular System

(2020) Mohammad Madjid et al.   JAMA Cardiology

Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China

(2020) Shaobo Shi et al.   JAMA Cardiology

Specific ACE2 expression in small intestinal enterocytes may cause gastrointestinal symptoms and injury after 2019-nCoV infection

(2020) Hui Zhang et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Reduction in ST-Segment Elevation Cardiac Catheterization Laboratory Activations in the United States During COVID-19 Pandemic

(2020) Santiago Garcia et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Clinical Characteristics of Hospitalized Individuals Dying With COVID-19 by Age Group in Italy

(2020) Luigi Palmieri et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Early postmortem brain MRI findings in COVID-19 non-survivors

(2020) Tim Coolen et al.   NEUROLOGY

The evidence of SARS-CoV-2 infection on ocular surface

(2020) Xian Zhang et al.   Ocular Surface

Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study

(2020) Julie Toubiana et al.   BMJ-British Medical Journal

Human blood vessel organoids as a model of diabetic vasculopathy

(2019) Reiner A. Wimmer et al.   NATURE

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

(2019) Alexandra C. Walls et al.   CELL

Pleiotropy and Specificity: Insights from the Interleukin 6 Family of Cytokines

(2019) Masaaki Murakami et al.   IMMUNITY

RhACE2 – playing an important role in inhibiting apoptosis induced by Ang II in HUVECs

(2019) Hongli Zhang et al.   MEDICINE

Relationship between circulating levels of angiotensin-converting enzyme 2-angiotensin-(1–7)-MAS axis and coronary heart disease

(2019) Xiaomin Zhou et al.   HEART AND VESSELS

Understanding Angiotensin II Type 1 Receptor Signaling in Vascular Pathophysiology

(2018) Satoru Eguchi et al.   HYPERTENSION

HIV-Associated Cancers and Related Diseases

(2018) Robert Yarchoan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

(2018) Robert N. Kirchdoerfer et al.   Scientific Reports

Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2

(2018) Wenfei Song et al.   PLoS Pathogens

Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

(2017) Rudragouda Channappanavar et al.   Seminars in Immunopathology

ACE2 Antagonizes VEGFa to Reduce Vascular Permeability During Acute Lung Injury

(2016) Xiaobo Yu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation

(2016) Minah Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

SARS and MERS: recent insights into emerging coronaviruses

(2016) Emmie de Wit et al.   NATURE REVIEWS MICROBIOLOGY

Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling

(2016) Georgina Espígol-Frigolé et al.   Science Signaling

Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling

(2016) Georgina Espígol-Frigolé et al.   Science Signaling

Activation of angiotensin II type 2 receptor suppresses TNF-α-induced ICAM-1viaNF-κB: possible role of ACE2

(2015) Liping Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes

(2015) Yang Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Angiotensin-Converting Enzyme 2 Inhibits Apoptosis of Pulmonary Endothelial Cells During Acute Lung Injury Through Suppressing SMAD2 Phosphorylation

(2015) Yong Ji et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Angiotensin-Converting Enzyme 2 Inhibits Apoptosis of Pulmonary Endothelial Cells During Acute Lung Injury Through Suppressing MiR-4262

(2015) Hong Bao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Isolation and Characterization of a Novel Bat Coronavirus Closely Related to the Direct Progenitor of Severe Acute Respiratory Syndrome Coronavirus

(2015) Xing-Lou Yang et al.   JOURNAL OF VIROLOGY

Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis

(2015) Jean Kaoru Millet et al.   VIRUS RESEARCH

Angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas axis prevents lipopolysaccharide–induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF–κB pathways

(2015) Yingchuan Li et al.   Scientific Reports

Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors

(2014) Raphael N. Vuille-dit-Bille et al.   AMINO ACIDS

ACE2: Angiotensin II/Angiotensin-(1–7) Balance in Cardiac and Renal Injury

(2014) Jasmina Varagic et al.   CURRENT HYPERTENSION REPORTS

The good, the bad, and the ugly of interleukin-6 signaling

(2014) J. J. Fuster et al.   EMBO JOURNAL

Angiotensin II Mediates Angiotensin Converting Enzyme Type 2 Internalization and Degradation Through an Angiotensin II Type I Receptor–Dependent Mechanism

(2014) Matthew R. Deshotels et al.   HYPERTENSION

Respiratory Tract Samples, Viral Load, and Genome Fraction Yield in Patients With Middle East Respiratory Syndrome

(2014) Ziad A. Memish et al.   JOURNAL OF INFECTIOUS DISEASES

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

(2014) Jan Mauer et al.   NATURE IMMUNOLOGY

New Perspectives in the Renin-Angiotensin-Aldosterone System (RAAS) IV: Circulating ACE2 as a Biomarker of Systolic Dysfunction in Human Hypertension and Heart Failure

(2014) Katalin Úri et al.   PLoS One

IL-6 in Inflammation, Immunity, and Disease

(2014) T. Tanaka et al.   Cold Spring Harbor Perspectives in Biology

Brain Angiotensin-Converting Enzyme Type 2 Shedding Contributes to the Development of Neurogenic Hypertension

(2013) Huijing Xia et al.   CIRCULATION RESEARCH

Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: A positive feedback mechanism in the RAS

(2013) Vaibhav B. Patel et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor

(2013) Xing-Yi Ge et al.   NATURE

Angiotensin-converting enzyme 2 activity in patients with chronic kidney disease

(2013) M. A. Roberts et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

N-Terminal Pro-Brain Natriuretic Peptide and Angiotensin-Converting Enzyme-2 Levels and Their Association With Postoperative Cardiac Complications After Emergency Orthopedic Surgery

(2012) Carol P. Chong et al.   AMERICAN JOURNAL OF CARDIOLOGY

Activation of the ACE2/Angiotensin-(1-7)/Mas Receptor Axis Enhances the Reparative Function of Dysfunctional Diabetic Endothelial Progenitors

(2012) Y. P. R. Jarajapu et al.   DIABETES

Cardioprotective Effects Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin 1-7 in Experimental Heart Failure in Angiotensin-Converting Enzyme 2–Null Mice

(2012) Vaibhav B. Patel et al.   HYPERTENSION

IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6

(2012) Stefan Rose-John   International Journal of Biological Sciences

Loss of angiotensin-converting enzyme 2 enhances TGF-β/Smad-mediated renal fibrosis and NF-κB-driven renal inflammation in a mouse model of obstructive nephropathy

(2012) Zhen Liu et al.   LABORATORY INVESTIGATION

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

(2012) Tatsuo Hashimoto et al.   NATURE

Impact of ACE2 Deficiency and Oxidative Stress on Cerebrovascular Function With Aging

(2012) Ricardo A. Peña Silva et al.   STROKE

Angiotensin-converting enzyme inhibition and fibrinolytic balance

(2011) Tetsuya Matsumoto et al.   HYPERTENSION RESEARCH

Circulating ACE2 activity is increased in patients with type 1 diabetes and vascular complications

(2011) Aino Soro-Paavonen et al.   JOURNAL OF HYPERTENSION

Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response

(2011) I. Glowacka et al.   JOURNAL OF VIROLOGY

Angiotensin-Converting Enzyme 2: The First Decade

(2011) Nicola E. Clarke et al.   International Journal of Hypertension

Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse

(2010) Merlin C. Thomas et al.   CIRCULATION RESEARCH

Angiotensin II–Mediated Microvascular Thrombosis

(2010) Elena Y. Senchenkova et al.   HYPERTENSION

Effects of ACE2 Inhibition in the Post-Myocardial Infarction Heart

(2010) Myung-A. Kim et al.   JOURNAL OF CARDIAC FAILURE

Efficient Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by the Transmembrane Protease TMPRSS2

(2010) S. Matsuyama et al.   JOURNAL OF VIROLOGY

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(2010) Rodrigo Fraga-Silva et al.   MOLECULAR MEDICINE

Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia

(2009) Hong Peng Jia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Soluble Angiotensin-Converting Enzyme 2 in Human Heart Failure: Relation With Myocardial Function and Clinical Outcomes

(2009) Slava Epelman et al.   JOURNAL OF CARDIAC FAILURE

Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis

(2008) Fina Lovren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiotensin-converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor

(2008) Rebecca A. Lew et al.   EXPERIMENTAL PHYSIOLOGY

A protein complex in the brush-border membrane explains a Hartnup disorder allele

(2008) Sonja Kowalczuk et al.   FASEB JOURNAL

Tissue-Specific Amino Acid Transporter Partners ACE2 and Collectrin Differentially Interact With Hartnup Mutations

(2008) Simone M.R. Camargo et al.   GASTROENTEROLOGY

Genetic variation in angiotensin-converting enzyme 2 gene is associated with extent of left ventricular hypertrophy in hypertrophic cardiomyopathy

(2008) Lize van der Merwe et al.   HUMAN GENETICS

Structure-Based Identification of Small-Molecule Angiotensin-Converting Enzyme 2 Activators as Novel Antihypertensive Agents

(2008) José A. Hernández Prada et al.   HYPERTENSION

Modulation of TNF- -converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-  production and facilitates viral entry

(2008) S. Haga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA