Angiotensin-Converting Enzyme 2: The First Decade

Angiotensin-Converting Enzyme 2 Ectodomain Shedding Cleavage-Site Identification: Determinants and Constraints

(2011) Zon W. Lai et al.   BIOCHEMISTRY

Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47phox NADPH oxidase subunit

(2011) Sreedhar Bodiga et al.   CARDIOVASCULAR RESEARCH

Lentivirus-mediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology

(2011) YanFei Qi et al.   EXPERIMENTAL PHYSIOLOGY

Regulated intramembrane proteolysis - lessons from amyloid precursor protein processing

(2011) Stefan F. Lichtenthaler et al.   JOURNAL OF NEUROCHEMISTRY

Gene transfer of angiotensin-converting enzyme 2 in the nucleus tractus solitarius improves baroreceptor heart rate reflex in spontaneously hypertensive rats

(2011) Masanobu Yamazato et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Regulation of angiotensin-converting enzyme 2 and Mas receptor by Ang-(1–7) in heart and kidney of spontaneously hypertensive rats

(2011) Zhen Tan et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

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(2011) Chun Liu et al.   MOLECULAR MEDICINE

ACE2/ANG-(1–7)/Mas pathway in the brain: the axis of good

(2010) Ping Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

(2010) JiuChang Zhong et al.   CIRCULATION

Angiotensin-Converting Enzyme 2: Central Regulator for Cardiovascular Function

(2010) Huijing Xia et al.   CURRENT HYPERTENSION REPORTS

Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases

(2010) Anderson J. Ferreira et al.   EXPERIMENTAL PHYSIOLOGY

ACE2 Overexpression Ameliorates Left Ventricular Remodeling and Dysfunction in a Rat Model of Myocardial Infarction

(2010) Yu Xia Zhao et al.   HUMAN GENE THERAPY

Prevention of Angiotensin II–Mediated Renal Oxidative Stress, Inflammation, and Fibrosis by Angiotensin-Converting Enzyme 2

(2010) JiuChang Zhong et al.   HYPERTENSION

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(2010) Rodrigo Fraga-Silva et al.   MOLECULAR MEDICINE

High sucrose intake in rats is associated with increased ACE2 and angiotensin-(1–7) levels in the adipose tissue

(2010) Michella Soares Coelho et al.   REGULATORY PEPTIDES

Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression

(2010) Jiu-Chang Zhong et al.   REGULATORY PEPTIDES

Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis

(2010) Koichi Murata et al.   ARTHRITIS RESEARCH & THERAPY

Selective and specific regulation of ectodomain shedding of angiotensin-converting enzyme 2 by tumor necrosis factor α-converting enzyme

(2009) Michikado Iwata et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia

(2009) Hong Peng Jia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Role of HIF-1α in the regulation ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells

(2009) Ruifeng Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Evidence for Angiotensin-converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension

(2009) Anderson J. Ferreira et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

TACE antagonists blocking ACE2 shedding caused by the spike protein of SARS-CoV are candidate antiviral compounds

(2009) Shiori Haga et al.   ANTIVIRAL RESEARCH

Brain-Selective Overexpression of Human Angiotensin-Converting Enzyme Type 2 Attenuates Neurogenic Hypertension

(2009) Yumei Feng et al.   CIRCULATION RESEARCH

Loss of Angiotensin-Converting Enzyme 2 Accelerates Maladaptive Left Ventricular Remodeling in Response to Myocardial Infarction

(2009) Zamaneh Kassiri et al.   Circulation-Heart Failure

Upregulation of angiotensin-converting enzyme (ACE) 2 in hepatic fibrosis by ACE inhibitors

(2009) Mao-liang Huang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy

(2009) G. Y. Oudit et al.   DIABETES

SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS

(2009) G. Y. Oudit et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Angiotensin II Type 1 Receptor–Mediated Reduction of Angiotensin-Converting Enzyme 2 Activity in the Brain Impairs Baroreflex Function in Hypertensive Mice

(2009) Huijing Xia et al.   HYPERTENSION

Targeting the Degradation of Angiotensin II With Recombinant Angiotensin-Converting Enzyme 2

(2009) Jan Wysocki et al.   HYPERTENSION

Effects of the ACE2 inhibitor GL1001 on acute dextran sodium sulfate-induced colitis in mice

(2009) John J. Byrnes et al.   INFLAMMATION RESEARCH

Cell Signaling, Internalization, and Nuclear Localization of the Angiotensin Converting Enzyme in Smooth Muscle and Endothelial Cells

(2009) Héctor A. Lucero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble Angiotensin-Converting Enzyme 2 in Human Heart Failure: Relation With Myocardial Function and Clinical Outcomes

(2009) Slava Epelman et al.   JOURNAL OF CARDIAC FAILURE

Differential Downregulation of ACE2 by the Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63

(2009) I. Glowacka et al.   JOURNAL OF VIROLOGY

Increased Insulin Sensitivity in Mice Lacking Collectrin, a Downstream Target of HNF-1α

(2009) Sandra M. Malakauskas et al.   MOLECULAR ENDOCRINOLOGY

17β-Estradiol modulates local cardiac renin-angiotensin system to prevent cardiac remodeling in the DOCA-salt model of hypertension in rats

(2009) V. Shenoy et al.   PEPTIDES

Chronic angiotensin (17) injection accelerates STZ-induced diabetic renal injury1

(2008) Ying SHAO et al.   ACTA PHARMACOLOGICA SINICA

Expression of ACE and ACE2 in Individuals With Diabetic Kidney Disease and Healthy Controls

(2008) Sonoo Mizuiri et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Angiotensin II Up-Regulates Angiotensin I-Converting Enzyme (ACE), but Down-Regulates ACE2 via the AT1-ERK/p38 MAP Kinase Pathway

(2008) Vijay Koka et al.   AMERICAN JOURNAL OF PATHOLOGY

MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides

(2008) Patricia E. Gallagher et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Regulation of ACE2 in cardiac myocytes and fibroblasts

(2008) Patricia E. Gallagher et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet

(2008) Manisha Gupte et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Overexpression of ACE2 Enhances Plaque Stability in a Rabbit Model of Atherosclerosis

(2008) Bo Dong et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Collectrin Is Involved in the Development of Salt-Sensitive Hypertension by Facilitating the Membrane Trafficking of Apical Membrane Proteins via Interaction With Soluble N -Ethylmaleiamide-Sensitive Factor Attachment Protein Receptor Complex

(2008) Akihiro Yasuhara et al.   CIRCULATION

Aldosterone, but Not Angiotensin II, Reduces Angiotensin Converting Enzyme 2 Gene Expression Levels in Cultured Neonatal Rat Cardiomyocytes

(2008) Megumi Yamamuro et al.   CIRCULATION JOURNAL

Angiotensin(1-7) Blunts Hypertensive Cardiac Remodeling by a Direct Effect on the Heart

(2008) Chantal Mercure et al.   CIRCULATION RESEARCH

ACE2 Deficiency Modifies Renoprotection Afforded by ACE Inhibition in Experimental Diabetes

(2008) C. Tikellis et al.   DIABETES

Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats

(2008) Debra I. Diz et al.   EXPERIMENTAL PHYSIOLOGY

Angiotensin-converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor

(2008) Rebecca A. Lew et al.   EXPERIMENTAL PHYSIOLOGY

Angiotensin-converting enzyme 2 gene targeting studies in mice: mixed messages

(2008) Susan B. Gurley et al.   EXPERIMENTAL PHYSIOLOGY

A protein complex in the brush-border membrane explains a Hartnup disorder allele

(2008) Sonja Kowalczuk et al.   FASEB JOURNAL

Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis

(2008) Christopher A. Rushworth et al.   FEBS Journal

Cardiac Overexpression of Angiotensin Converting Enzyme 2 Protects the Heart From Ischemia-Induced Pathophysiology

(2008) Shant Der Sarkissian et al.   HYPERTENSION

Transgenic Angiotensin-Converting Enzyme 2 Overexpression in Vessels of SHRSP Rats Reduces Blood Pressure and Improves Endothelial Function

(2008) Brit Rentzsch et al.   HYPERTENSION

Structure-Based Identification of Small-Molecule Angiotensin-Converting Enzyme 2 Activators as Novel Antihypertensive Agents

(2008) José A. Hernández Prada et al.   HYPERTENSION

Comparative expression analysis of the renin–angiotensin system components between white and brown perivascular adipose tissue

(2008) B Gálvez-Prieto et al.   JOURNAL OF ENDOCRINOLOGY

The sweeter side of ACE2: Physiological evidence for a role in diabetes

(2008) Sharell M. Bindom et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Modulation of TNF- -converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-  production and facilitates viral entry

(2008) S. Haga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA