Diverse noncoding mutations contribute to deregulation of cis-regulatory landscape in pediatric cancers
出版年份 2020 全文链接
标题
Diverse noncoding mutations contribute to deregulation of cis-regulatory landscape in pediatric cancers
作者
关键词
-
出版物
Science Advances
Volume 6, Issue 30, Pages eaba3064
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2020-07-25
DOI
10.1126/sciadv.aba3064
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- TERT promoter mutations and telomeres during tumorigenesis
- (2020) Franziska K Lorbeer et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- First case of AML with rare chromosome translocations: a case report of twins
- (2018) Lin Wang et al. BMC CANCER
- Activation of transglutaminase 2 by nerve growth factor in differentiating neuroblastoma cells: A role in cell survival and neurite outgrowth
- (2018) Alanood S. Algarni et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome
- (2018) Aniththa Thivakaran et al. HAEMATOLOGICA
- The landscape of genomic alterations across childhood cancers
- (2018) Susanne N. Gröbner et al. NATURE
- A global transcriptional network connecting noncoding mutations to changes in tumor gene expression
- (2018) Wei Zhang et al. NATURE GENETICS
- MYCN-amplified neuroblastoma maintains an aggressive and undifferentiated phenotype by deregulation of estrogen and NGF signaling
- (2018) Johanna Dzieran et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ZNF281 inhibits neuronal differentiation and is a prognostic marker for neuroblastoma
- (2018) Marco Pieraccioli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome
- (2018) Aniththa Thivakaran et al. HAEMATOLOGICA
- Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours
- (2018) Xiaotu Ma et al. NATURE
- The genetic basis and cell of origin of mixed phenotype acute leukaemia
- (2018) Thomas B. Alexander et al. NATURE
- Coexisting and cooperating mutations in NPM1 -mutated acute myeloid leukemia
- (2017) Jay L. Patel et al. LEUKEMIA RESEARCH
- Molecular insights of Gas6/TAM in cancer development and therapy
- (2017) Guiling Wu et al. Cell Death & Disease
- Genomic characterization of paediatric acute lymphoblastic leukaemia: an opportunity for precision medicine therapeutics
- (2016) Sarah K. Tasian et al. BRITISH JOURNAL OF HAEMATOLOGY
- Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities ofEP300andCREBBP
- (2016) Maoxiang Qian et al. GENOME RESEARCH
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- (2016) John G Doench et al. NATURE BIOTECHNOLOGY
- An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma
- (2016) Yotam Drier et al. NATURE GENETICS
- The genomic landscape of core-binding factor acute myeloid leukemias
- (2016) Zachary J Faber et al. NATURE GENETICS
- Atg3 Overexpression Enhances Bortezomib-Induced Cell Death in SKM-1 Cell
- (2016) Lin Zhuang et al. PLoS One
- Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation
- (2015) J. Sperlazza et al. BLOOD
- Telomerase activation by genomic rearrangements in high-risk neuroblastoma
- (2015) Martin Peifer et al. NATURE
- Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism
- (2015) Derek A. Oldridge et al. NATURE
- dbSUPER: a database of super-enhancers in mouse and human genome
- (2015) Aziz Khan et al. NUCLEIC ACIDS RESEARCH
- ccmGDB: a database for cancer cell metabolism genes
- (2015) Pora Kim et al. NUCLEIC ACIDS RESEARCH
- Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma
- (2015) R. J. H. Ryan et al. Cancer Discovery
- Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia
- (2015) Kathryn G. Roberts et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells
- (2015) Loris De Cecco et al. PLoS One
- Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity
- (2014) Matthew T. Weirauch et al. CELL
- A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia
- (2014) Stefan Gröschel et al. CELL
- Complex correlations: replication timing and mutational landscapes during cancer and genome evolution
- (2014) Jiao Sima et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Mi-2/NuRD chromatin remodeling complexes regulate B and T-lymphocyte development and function
- (2014) Carissa Dege et al. IMMUNOLOGICAL REVIEWS
- Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
- (2014) Paul A. Northcott et al. NATURE
- Integrating human sequence data sets provides a resource of benchmark SNP and indel genotype calls
- (2014) Justin M Zook et al. NATURE BIOTECHNOLOGY
- Improved vectors and genome-wide libraries for CRISPR screening
- (2014) Neville E Sanjana et al. NATURE METHODS
- Growth Factor Independence 1b (Gfi1b) Is Important for the Maturation of Erythroid Cells and the Regulation of Embryonic Globin Expression
- (2014) Lothar Vassen et al. PLoS One
- Global view of enhancer-promoter interactome in human cells
- (2014) B. He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma
- (2014) Jennifer A. Perry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
- (2014) M. R. Mansour et al. SCIENCE
- The landscape of kinase fusions in cancer
- (2014) Nicolas Stransky et al. Nature Communications
- Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR–Cas9 system
- (2014) R. Torres et al. Nature Communications
- Diverse Mechanisms of Somatic Structural Variations in Human Cancer Genomes
- (2013) Lixing Yang et al. CELL
- Super-Enhancers in the Control of Cell Identity and Disease
- (2013) Denes Hnisz et al. CELL
- Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis
- (2013) Victoria Moignard et al. NATURE CELL BIOLOGY
- The genetic landscape of high-risk neuroblastoma
- (2013) Trevor J Pugh et al. NATURE GENETICS
- GCN5 acetylates and regulates the stability of the oncoprotein E2A-PBX1 in acute lymphoblastic leukemia
- (2012) T Holmlund et al. LEUKEMIA
- Transglutaminase 6: a protein associated with central nervous system development and motor function
- (2011) Helen Thomas et al. AMINO ACIDS
- FIMO: scanning for occurrences of a given motif
- (2011) Charles E. Grant et al. BIOINFORMATICS
- Prevalence and prognostic value of IDH1 and IDH2 mutations in childhood AML: a study of the AML–BFM and DCOG study groups
- (2011) F Damm et al. LEUKEMIA
- Discover regulatory DNA elements using chromatin signatures and artificial neural network
- (2010) Hiram A. Firpi et al. BIOINFORMATICS
- Prognostic significance of HER2 expression in neuroblastic tumors
- (2010) Ewa Izycka-Swieszewska et al. MODERN PATHOLOGY
- International network of cancer genome projects
- (2010) Thomas J. Hudson (Chairperson) et al. NATURE
- Sequencing newly replicated DNA reveals widespread plasticity in human replication timing
- (2009) R. S. Hansen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ReplicationDomain: a visualization tool and comparative database for genome-wide replication timing data
- (2008) Nodin Weddington et al. BMC BIOINFORMATICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search