An orthogonally regulatable DNA nanodevice for spatiotemporally controlled biorecognition and tumor treatment

NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices

(2019) Hongqian Chu et al.   Nature Communications

Activating Antitumor Immunity and Antimetastatic Effect Through Polydopamine‐Encapsulated Core–Shell Upconversion Nanoparticles

(2019) Shuangqian Yan et al.   ADVANCED MATERIALS

Building machines with DNA molecules

(2019) Hamid Ramezani et al.   NATURE REVIEWS GENETICS

Optochemical Control of Biological Processes in Cells and Animals

(2018) Nicholas Ankenbruck et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Upconversion Luminescence-Activated DNA Nanodevice for ATP Sensing in Living Cells

(2018) Jian Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics

(2018) Shuo Chen et al.   SCIENCE

Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses

(2018) Yu Chao et al.   Nature Biomedical Engineering

A DNA nanomachine chemically resolves lysosomes in live cells

(2018) KaHo Leung et al.   Nature Nanotechnology

Heterodimers Made of Upconversion Nanoparticles and Metal–Organic Frameworks

(2017) Yifan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Illuminating developmental biology through photochemistry

(2017) Lukasz Kowalik et al.   Nature Chemical Biology

Cell-targetable DNA nanocapsules for spatiotemporal release of caged bioactive small molecules

(2017) Aneesh T. Veetil et al.   Nature Nanotechnology

Antibody-powered nucleic acid release using a DNA-based nanomachine

(2017) Simona Ranallo et al.   Nature Communications

External triggering and triggered targeting strategies for drug delivery

(2017) Yanfei Wang et al.   Nature Reviews Materials

Photodynamic Therapy Mediated by Nontoxic Core–Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer

(2016) Xiaopin Duan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Light-controlled modulation of gene expression by chemical optoepigenetic probes

(2016) Surya A Reis et al.   Nature Chemical Biology

A biomimetic DNA-based channel for the ligand-controlled transport of charged molecular cargo across a biological membrane

(2016) Jonathan R. Burns et al.   Nature Nanotechnology

Lanthanide Nanoparticles: From Design toward Bioimaging and Therapy

(2015) Hao Dong et al.   CHEMICAL REVIEWS

DNA-Mediated Cellular Delivery of Functional Enzymes

(2015) Jeffrey D. Brodin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorescence Activation Imaging of Cytochrome c Released from Mitochondria Using Aptameric Nanosensor

(2015) Ting-Ting Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoscale optomechanical actuators for controlling mechanotransduction in living cells

(2015) Zheng Liu et al.   NATURE METHODS

Computing in mammalian cells with nucleic acid strand exchange

(2015) Benjamin Groves et al.   Nature Nanotechnology

DNA nanotechnology from the test tube to the cell

(2015) Yuan-Jyue Chen et al.   Nature Nanotechnology

Universal computing by DNA origami robots in a living animal

(2014) Yaniv Amir et al.   Nature Nanotechnology

Aptamer photoregulation in vivo

(2014) Lele Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP-triggered anticancer drug delivery

(2014) Ran Mo et al.   Nature Communications

Optical control of antibacterial activity

(2013) Willem A. Velema et al.   Nature Chemistry

Autonomous molecular cascades for evaluation of cell surfaces

(2013) Maria Rudchenko et al.   Nature Nanotechnology

Targeting neurons and photons for optogenetics

(2013) Adam M Packer et al.   NATURE NEUROSCIENCE

Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics

(2013) G. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers

(2012) Niagara Muhammad Idris et al.   NATURE MEDICINE

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Broadband dye-sensitized upconversion of near-infrared light

(2012) Wenqiang Zou et al.   Nature Photonics

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

(2011) Makoto Mitsunaga et al.   NATURE MEDICINE

A New Paradigm for Aptamer Therapeutic AS1411 Action: Uptake by Macropinocytosis and Its Stimulation by a Nucleolin-Dependent Mechanism

(2010) E. M. Reyes-Reyes et al.   CANCER RESEARCH

Molecular robots guided by prescriptive landscapes

(2010) Kyle Lund et al.   NATURE

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

A DNA nanomachine that maps spatial and temporal pH changes inside living cells

(2009) Souvik Modi et al.   Nature Nanotechnology