EED-mediated histone methylation is critical for CNS myelination and remyelination by inhibiting WNT, BMP, and senescence pathways
出版年份 2020 全文链接
标题
EED-mediated histone methylation is critical for CNS myelination and remyelination by inhibiting WNT, BMP, and senescence pathways
作者
关键词
-
出版物
Science Advances
Volume 6, Issue 33, Pages eaaz6477
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2020-08-13
DOI
10.1126/sciadv.aaz6477
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis
- (2019) Alexandra M. Nicaise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Three additional patients with EED-associated overgrowth: potential mutation hotspots identified?
- (2019) Catherine J. Spellicy et al. JOURNAL OF HUMAN GENETICS
- Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis
- (2019) Qinjie Weng et al. Cell Stem Cell
- PRC2 is high maintenance
- (2019) Jia-Ray Yu et al. GENES & DEVELOPMENT
- Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation
- (2019) Anne Laugesen et al. MOLECULAR CELL
- Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model
- (2019) Peisu Zhang et al. NATURE NEUROSCIENCE
- Cellular Senescence: Aging, Cancer, and Injury
- (2019) Arianna Calcinotto et al. PHYSIOLOGICAL REVIEWS
- Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair
- (2018) Chuntao Zhao et al. DEVELOPMENTAL CELL
- Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways
- (2018) Takahiro Ito et al. Cell Reports
- Targeting senescence to delay progression of multiple sclerosis
- (2018) Wendy Oost et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Polycomb repression regulates Schwann cell proliferation and axon regeneration after nerve injury
- (2018) Ki H. Ma et al. GLIA
- Myelination and mTOR
- (2017) Gianluca Figlia et al. GLIA
- Senescence-associated reprogramming promotes cancer stemness
- (2017) Maja Milanovic et al. NATURE
- lncRNA Functional Networks in Oligodendrocytes Reveal Stage-Specific Myelination Control by an lncOL1 /Suz12 Complex in the CNS
- (2017) Danyang He et al. NEURON
- EED orchestration of heart maturation through interaction with HDACs is H3K27me3-independent
- (2017) Shanshan Ai et al. eLife
- NovelEEDmutation in patient with Weaver syndrome
- (2016) Erin Cooney et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma
- (2016) Fanghui Lu et al. CANCER CELL
- Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch
- (2016) Liguo Zhang et al. DEVELOPMENTAL CELL
- A proton spectroscopy study of white matter in children with autism
- (2016) Antonio Y. Hardan et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer
- (2016) Anne Laugesen et al. Cold Spring Harbor Perspectives in Medicine
- Cellular senescence: from growth arrest to immunogenic conversion
- (2015) D. G. A. Burton et al. AGE
- Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway
- (2015) Fu-Zheng Wei et al. Autophagy
- Dynamics and Mechanisms of CNS Myelination
- (2015) Kathryn K. Bercury et al. DEVELOPMENTAL CELL
- Regulation of Peripheral Nerve Myelin Maintenance by Gene Repression through Polycomb Repressive Complex 2
- (2015) K. H. Ma et al. JOURNAL OF NEUROSCIENCE
- Chromatin Landscape Defined by Repressive Histone Methylation during Oligodendrocyte Differentiation
- (2015) J. Liu et al. JOURNAL OF NEUROSCIENCE
- Nuclear pore complex remodeling by p75NTR cleavage controls TGF-β signaling and astrocyte functions
- (2015) Christian Schachtrup et al. NATURE NEUROSCIENCE
- Glia Disease and Repair—Remyelination
- (2015) Robin J.M. Franklin et al. Cold Spring Harbor Perspectives in Biology
- Chromatin Repressive Complexes in Stem Cells, Development, and Cancer
- (2014) Anne Laugesen et al. Cell Stem Cell
- The translational biology of remyelination: Past, present, and future
- (2014) Robin J. M. Franklin et al. GLIA
- PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies
- (2014) Thomas De Raedt et al. NATURE
- Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors
- (2014) Ming Zhang et al. NATURE GENETICS
- The central role of EED in the orchestration of polycomb group complexes
- (2014) Qi Cao et al. Nature Communications
- mTOR: A Link from the Extracellular Milieu to Transcriptional Regulation of Oligodendrocyte Development
- (2013) Teresa L. Wood et al. ASN Neuro
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Chromatin modifiers and remodellers: regulators of cellular differentiation
- (2013) Taiping Chen et al. NATURE REVIEWS GENETICS
- Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
- (2013) P. W. Lewis et al. SCIENCE
- Ezh1 Is Required for Hematopoietic Stem Cell Maintenance and Prevents Senescence-like Cell Cycle Arrest
- (2012) Isabel Hidalgo et al. Cell Stem Cell
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
- (2012) Jeremy Schwartzentruber et al. NATURE
- A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
- (2012) Laurens Kruidenier et al. NATURE
- Dual-Mode Modulation of Smad Signaling by Smad-Interacting Protein Sip1 Is Required for Myelination in the Central Nervous System
- (2012) Qinjie Weng et al. NEURON
- Mutations in EZH2 Cause Weaver Syndrome
- (2011) William T. Gibson et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Huntingtin facilitates polycomb repressive complex 2
- (2009) Ihn Sik Seong et al. HUMAN MOLECULAR GENETICS
- Role of the polycomb protein EED in the propagation of repressive histone marks
- (2009) Raphael Margueron et al. NATURE
- HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction
- (2009) Feng Ye et al. NATURE NEUROSCIENCE
- A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
- (2009) Linda Madisen et al. NATURE NEUROSCIENCE
- Ezh1 and Ezh2 Maintain Repressive Chromatin through Different Mechanisms
- (2008) Raphael Margueron et al. MOLECULAR CELL
- EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency
- (2008) Xiaohua Shen et al. MOLECULAR CELL
- PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice
- (2008) Leanne E Rivers et al. NATURE NEUROSCIENCE
- Remyelination in the CNS: from biology to therapy
- (2008) Robin J. M. Franklin et al. NATURE REVIEWS NEUROSCIENCE
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