Angiotensin Receptors Heterodimerization and Trafficking: How Much Do They Influence Their Biological Function?
出版年份 2020 全文链接
标题
Angiotensin Receptors Heterodimerization and Trafficking: How Much Do They Influence Their Biological Function?
作者
关键词
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出版物
Frontiers in Pharmacology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-08-04
DOI
10.3389/fphar.2020.01179
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Therapeutic Potential of Targeting ß-Arrestin
- (2019) Richard A. Bond et al. Frontiers in Pharmacology
- The Renin-Angiotensin System: Going Beyond the Classical Paradigms
- (2019) Robson A. Souza Santos et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- G protein-coupled receptor trafficking and signaling: new insights into the enteric nervous system
- (2019) Simona E. Carbone et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Revealing Adenosine A2A-Dopamine D2 Receptor Heteromers in Parkinson’s Disease Post-Mortem Brain through a New AlphaScreen-Based Assay
- (2019) Víctor Fernández-Dueñas et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nuclear G-protein-coupled receptors as putative novel pharmacological targets
- (2019) Rita Ribeiro-Oliveira et al. DRUG DISCOVERY TODAY
- The Role of β-Arrestin Proteins in Organization of Signaling and Regulation of the AT1 Angiotensin Receptor
- (2019) Gábor Turu et al. Frontiers in Endocrinology
- Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain
- (2019) Jeffri S. Retamal et al. Frontiers in Molecular Neuroscience
- Mas receptor is translocated to the nucleus upon agonist stimulation in brainstem neurons from spontaneously hypertensive rats but not normotensive rats
- (2019) Flavia M Cerniello et al. CARDIOVASCULAR RESEARCH
- The role of G protein-coupled receptor kinases in the pathology of malignant tumors
- (2018) Wu-yi Sun et al. ACTA PHARMACOLOGICA SINICA
- Internalization of G-protein-coupled receptors: Implication in receptor function, physiology and diseases
- (2018) Davide Calebiro et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Novel mechanisms of G-protein-coupled receptors functions: AT 1 angiotensin receptor acts as a signaling hub and focal point of receptor cross-talk
- (2018) András D. Tóth et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- G protein-coupled receptor kinase 2 (GRK2) as an integrative signalling node in the regulation of cardiovascular function and metabolic homeostasis
- (2018) Federico Mayor et al. CELLULAR SIGNALLING
- GPCR desensitization: Acute and prolonged phases
- (2018) Sudarshan Rajagopal et al. CELLULAR SIGNALLING
- The Role of G Protein-coupled Receptor Kinases in Cancer
- (2018) Shan Yu et al. International Journal of Biological Sciences
- Intracrine action of angiotensin II in mesangial cells: subcellular distribution of angiotensin II receptor subtypes AT1 and AT2
- (2018) Antônio da Silva Novaes et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology
- (2018) Steven J. Forrester et al. PHYSIOLOGICAL REVIEWS
- The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7)
- (2018) Robson Augusto Souza Santos et al. PHYSIOLOGICAL REVIEWS
- The mechanisms behind decreased internalization of angiotensin II type 1 receptor
- (2018) Jingwei Bian et al. VASCULAR PHARMACOLOGY
- G-Protein–Coupled Receptors in Heart Disease
- (2018) Jialu Wang et al. CIRCULATION RESEARCH
- Mechanisms of signalling and biased agonism in G protein-coupled receptors
- (2018) Denise Wootten et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Therapeutic Targeting of Endosomal G-Protein-Coupled Receptors
- (2018) Alex R.B. Thomsen et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Beta-Arrestin1 Prevents Preeclampsia by Downregulation of Mechanosensitive AT1-B2 Receptor Heteromers
- (2018) Ursula Quitterer et al. CELL
- Role of βarrestin1 in AT1 R-mediated mitogen-activated protein kinase activation in Wistar and SHR brainstem astrocytes
- (2018) Shmuel Negussie et al. JOURNAL OF NEUROCHEMISTRY
- When trafficking and signaling mix: how subcellular location shapes GPCR activation of heterotrimeric G proteins
- (2018) Braden T. Lobingier et al. TRAFFIC
- β-Arrestin Based Receptor Signaling Paradigms: Potential Therapeutic Targets for Complex Age-Related Disorders
- (2018) Jaana van Gastel et al. Frontiers in Pharmacology
- Angiotensin II Type 2 Receptor and Receptor Mas Are Colocalized and Functionally Interdependent in Obese Zucker Rat KidneyNovelty and Significance
- (2017) Sanket N. Patel et al. HYPERTENSION
- Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MASNovelty and Significance
- (2017) Julia Leonhardt et al. HYPERTENSION
- MAS1 Receptor Trafficking Involves ERK1/2 Activation Through a β-Arrestin2–Dependent PathwayNovelty and Significance
- (2017) Flavia M. Cerniello et al. HYPERTENSION
- Heterologous phosphorylation–induced formation of a stability lock permits regulation of inactive receptors by β-arrestins
- (2017) András D. Tóth et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Angiotensin II activates CaV 1.2 Ca2+ channels through β-arrestin2 and casein kinase 2 in mouse immature cardiomyocytes
- (2017) Toshihide Kashihara et al. JOURNAL OF PHYSIOLOGY-LONDON
- Angiotensin type 1A receptor regulates β-arrestin binding of the β2-adrenergic receptor via heterodimerization
- (2017) András D. Tóth et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Paracrine and Intracrine Angiotensin 1-7/Mas Receptor Axis in the Substantia Nigra of Rodents, Monkeys, and Humans
- (2017) Maria A. Costa-Besada et al. MOLECULAR NEUROBIOLOGY
- Biased agonism/antagonism at the AngII-AT1 receptor: Implications for adrenal aldosterone production and cardiovascular therapy
- (2017) Jennifer Maning et al. PHARMACOLOGICAL RESEARCH
- An update on the physiological and therapeutic relevance of GPCR oligomers
- (2017) Batoul Farran PHARMACOLOGICAL RESEARCH
- The Diverse Roles of Arrestin Scaffolds in G Protein–Coupled Receptor Signaling
- (2017) Yuri K. Peterson et al. PHARMACOLOGICAL REVIEWS
- Preeclampsia: A review of the pathogenesis and possible management strategies based on its pathophysiological derangements
- (2017) Amel A.F. El-Sayed Taiwanese Journal of Obstetrics & Gynecology
- The intracellular angiotensin system buffers deleterious effects of the extracellular paracrine system
- (2017) Begoña Villar-Cheda et al. Cell Death & Disease
- Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling
- (2017) Chun-Hua Liu et al. Nature Communications
- Intracellular Angiotensin‐II Interacts With Nuclear Angiotensin Receptors in Cardiac Fibroblasts and Regulates RNA Synthesis, Cell Proliferation, and Collagen Secretion
- (2017) Artavazd Tadevosyan et al. Journal of the American Heart Association
- Prolonged AT1R activation induces CaV1.2 channel internalization in rat cardiomyocytes
- (2017) Tamara Hermosilla et al. Scientific Reports
- G Protein–Coupled Receptor Heteromers
- (2016) Ivone Gomes et al. Annual Review of Pharmacology and Toxicology
- Cardiac Fibroblast GRK2 Deletion Enhances Contractility and Remodeling Following Ischemia/Reperfusion InjuryNovelty and Significance
- (2016) Meryl C. Woodall et al. CIRCULATION RESEARCH
- Preeclampsia; short and long-term consequences for mother and neonate
- (2016) Anouk Bokslag et al. EARLY HUMAN DEVELOPMENT
- Cardioprotective Angiotensin-(1–7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 ReceptorNovelty and Significance
- (2016) Ségolène Galandrin et al. HYPERTENSION
- Heteromerization Between the Bradykinin B2Receptor and the Angiotensin-(1–7) Mas ReceptorNovelty and Significance
- (2016) Bruno D. Cerrato et al. HYPERTENSION
- Structure and Function of Cross-class Complexes of G Protein-coupled Secretin and Angiotensin 1a Receptors
- (2016) Kaleeckal G. Harikumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- “Canonical and non-canonical actions of GRK5 in the heart”
- (2016) Christopher J. Traynham et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- G protein-coupled receptor kinases as regulators of dopamine receptor functions
- (2016) Eugenia V. Gurevich et al. PHARMACOLOGICAL RESEARCH
- Purinergic P2Y6receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II–induced hypertension
- (2016) Akiyuki Nishimura et al. Science Signaling
- Purinergic P2Y6receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II–induced hypertension
- (2016) Akiyuki Nishimura et al. Science Signaling
- Role of PKCδ in Enhanced Expression of Gqα/PLCβ1 Proteins and VSMC Hypertrophy in Spontaneously Hypertensive Rats
- (2016) Mohammed Emehdi Atef et al. PLoS One
- Attenuation of ligand-induced activation of angiotensin II type 1 receptor signaling by the type 2 receptor via protein kinase C
- (2016) Takayuki Inuzuka et al. Scientific Reports
- Dopamine D2 and angiotensin II type 1 receptors form functional heteromers in rat striatum
- (2015) E. Martínez-Pinilla et al. BIOCHEMICAL PHARMACOLOGY
- Multifaceted role of β-arrestins in inflammation and disease
- (2015) D Sharma et al. GENES AND IMMUNITY
- Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice
- (2015) Joshua Abd Alla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GRK2 compromises cardiomyocyte mitochondrial function by diminishing fatty acid-mediated oxygen consumption and increasing superoxide levels
- (2015) Priscila Y. Sato et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Dual agonist occupancy of AT1-R–α2C-AR heterodimers results in atypical Gs-PKA signaling
- (2015) Morgane Bellot et al. Nature Chemical Biology
- Targeting β-arrestin2 in the treatment of l-DOPA–induced dyskinesia in Parkinson’s disease
- (2015) Nikhil M. Urs et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Paroxetine-mediated GRK2 inhibition reverses cardiac dysfunction and remodeling after myocardial infarction
- (2015) Sarah M. Schumacher et al. Science Translational Medicine
- Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison
- (2015) Samalia Dabul et al. Scientific Reports
- Functional Interaction between Angiotensin II Receptor Type 1 and Chemokine (C-C Motif) Receptor 2 with Implications for Chronic Kidney Disease
- (2015) Mohammed Akli Ayoub et al. PLoS One
- Downregulation of G protein-coupled receptor kinase 2 levels enhances cardiac insulin sensitivity and switches on cardioprotective gene expression patterns
- (2014) Elisa Lucas et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Angiotensin II Type I and Prostaglandin F2α Receptors Cooperatively Modulate Signaling in Vascular Smooth Muscle Cells
- (2014) Eugénie Goupil et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Different Potencies of Angiotensin Receptor Blockers at Suppressing Adrenal β-Arrestin1–Dependent Post-Myocardial Infarction Hyperaldosteronism
- (2014) Anastasios Lymperopoulos et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Nuclear expression of renin-angiotensin system components in NRK-52E renal epithelial cells
- (2014) Ebaa M Alzayadneh et al. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
- Nuclear Localization of α1A‐Adrenergic Receptors Is Required for Signaling in Cardiac Myocytes: An “Inside‐Out” α1‐AR Signaling Pathway
- (2014) Steven C. Wu et al. Journal of the American Heart Association
- Update on the Angiotensin Converting Enzyme 2-Angiotensin (1–7)-Mas Receptor Axis: Fetal Programing, Sex Differences, and Intracellular Pathways
- (2014) Mark C. Chappell et al. Frontiers in Endocrinology
- Phospholipase Cε Hydrolyzes Perinuclear Phosphatidylinositol 4-Phosphate to Regulate Cardiac Hypertrophy
- (2013) Lianghui Zhang et al. CELL
- Discovery and Characterization of Alamandine
- (2013) Roberto Queiroga Lautner et al. CIRCULATION RESEARCH
- Nuclear Mechanics and Mechanotransduction in Health and Disease
- (2013) Philipp Isermann et al. CURRENT BIOLOGY
- Role of GRK4 in the Regulation of Arterial AT 1 Receptor in Hypertension
- (2013) Ken Chen et al. HYPERTENSION
- The Arrestin-selective Angiotensin AT1Receptor Agonist [Sar1,Ile4,Ile8]-AngII Negatively Regulates Bradykinin B2Receptor Signaling via AT1-B2Receptor Heterodimers
- (2013) Parker C. Wilson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracrine endothelin signaling evokes IP3-dependent increases in nucleoplasmic Ca2+ in adult cardiac myocytes
- (2013) Clémence Merlen et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Regulation of cardiac nitric oxide signaling by nuclear β-adrenergic and endothelin receptors
- (2013) George Vaniotis et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Convergence of G Protein-Coupled Receptor and S-Nitrosylation Signaling Determines the Outcome to Cardiac Ischemic Injury
- (2013) Z. M. Huang et al. Science Signaling
- β-Arrestin-biased AT1R stimulation promotes cell survival during acute cardiac injury
- (2012) Ki-Seok Kim et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- The apelin receptor inhibits the angiotensin II type 1 receptor via allosteric trans-inhibition
- (2012) K Siddiquee et al. BRITISH JOURNAL OF PHARMACOLOGY
- Receptors and ionic transporters in nuclear membranes: new targets for therapeutical pharmacological interventions
- (2012) Ghassan Bkaily et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- TRV120027, a Novel β-Arrestin Biased Ligand at the Angiotensin II Type I Receptor, Unloads the Heart and Maintains Renal Function When Added to Furosemide in Experimental Heart Failure
- (2012) Guido Boerrigter et al. Circulation-Heart Failure
- The intracrine renin–angiotensin system
- (2012) Rajesh Kumar et al. CLINICAL SCIENCE
- AAV6. ARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model
- (2012) P. W. J. Raake et al. EUROPEAN HEART JOURNAL
- Involvement of β-arrestins in cancer progression
- (2012) Shanshan Hu et al. MOLECULAR BIOLOGY REPORTS
- Nuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signaling
- (2011) George Vaniotis et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Review: Novel roles of nuclear angiotensin receptors and signaling mechanisms
- (2011) TanYa M. Gwathmey et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Review: Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidney
- (2011) Brianne Ellis et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Review: Lessons from in vitro studies and a related intracellular angiotensin II transgenic mouse model
- (2011) Julia L. Cook et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- A cleavable signal peptide enhances cell surface delivery and heterodimerization of Cerulean-tagged angiotensin II AT1 and bradykinin B2 receptor
- (2011) Ursula Quitterer et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nuclear localization drives α1-adrenergic receptor oligomerization and signaling in cardiac myocytes
- (2011) Casey D. Wright et al. CELLULAR SIGNALLING
- AT1R-CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II
- (2011) Raphael Rozenfeld et al. EMBO JOURNAL
- Determination of the Exact Molecular Requirements for Type 1 Angiotensin Receptor Epidermal Growth Factor Receptor Transactivation and Cardiomyocyte Hypertrophy
- (2011) Nicola J. Smith et al. HYPERTENSION
- G protein-coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function
- (2011) Artavazd Tadevosyan et al. JOURNAL OF PHYSIOLOGY-LONDON
- Adrenal Beta-Arrestin 1 Inhibition In Vivo Attenuates Post-Myocardial Infarction Progression to Heart Failure and Adverse Remodeling Via Reduction of Circulating Aldosterone Levels
- (2011) Anastasios Lymperopoulos et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Nuclear-delimited Angiotensin Receptor-mediated Signaling Regulates Cardiomyocyte Gene Expression
- (2010) Artavazd Tadevosyan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Selectively Engaging -Arrestins at the Angiotensin II Type 1 Receptor Reduces Blood Pressure and Increases Cardiac Performance
- (2010) J. D. Violin et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The angiotensin II–AT1 receptor stimulates reactive oxygen species within the cell nucleus
- (2009) Karl D. Pendergrass et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The intracellular renin-angiotensin system in the heart
- (2009) Rajesh Kumar et al. CURRENT HYPERTENSION REPORTS
- The role of dimerisation in the cellular trafficking of G-protein-coupled receptors
- (2009) Graeme Milligan CURRENT OPINION IN PHARMACOLOGY
- Cell Signaling, Internalization, and Nuclear Localization of the Angiotensin Converting Enzyme in Smooth Muscle and Endothelial Cells
- (2009) Héctor A. Lucero et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracellular ANG II directly induces in vitro transcription of TGF-β1, MCP-1, and NHE-3 mRNAs in isolated rat renal cortical nuclei via activation of nuclear AT1a receptors
- (2008) Xiao C. Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- G Protein–Coupled Receptor Kinase 2 Ablation in Cardiac Myocytes Before or After Myocardial Infarction Prevents Heart Failure
- (2008) Philip W. Raake et al. CIRCULATION RESEARCH
- Intracellular Angiotensin II Production in Diabetic Rats Is Correlated With Cardiomyocyte Apoptosis, Oxidative Stress, and Cardiac Fibrosis
- (2008) V. P. Singh et al. DIABETES
- Angiotensin II AT2Receptor Oligomers Mediate G-protein Dysfunction in an Animal Model of Alzheimer Disease
- (2008) Said AbdAlla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expression of Angiotensin-converting Enzyme Changes Major Histocompatibility Complex Class I Peptide Presentation by Modifying C Termini of Peptide Precursors
- (2008) Xiao Z. Shen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lack of Evidence for AT1R/B2R Heterodimerization in COS-7, HEK293, and NIH3T3 Cells
- (2008) Jakob L. Hansen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation
- (2008) Martin Savard et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells
- (2008) Hewang Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Endothelin-1 enhances nuclear Ca2+ transients in atrial myocytes through Ins(1,4,5)P3-dependent Ca2+ release from perinuclear Ca2+ stores
- (2007) J. Kockskamper et al. JOURNAL OF CELL SCIENCE
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