Dual agonist occupancy of AT1-R–α2C-AR heterodimers results in atypical Gs-PKA signaling

Probing Heterotrimeric G Protein Activation: Applications to Biased Ligands

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European Guidelines on cardiovascular disease prevention in clinical practice (version 2012): The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts) * Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)

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Deciphering biased-agonism complexity reveals a new active AT1 receptor entity

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Apo-Ghrelin Receptor Forms Heteromers with DRD2 in Hypothalamic Neurons and Is Essential for Anorexigenic Effects of DRD2 Agonism

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Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland

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AT1R-CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II

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Full characterization of GPCR monomer–dimer dynamic equilibrium by single molecule imaging

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CODA-RET reveals functional selectivity as a result of GPCR heteromerization

(2011) Eneko Urizar et al.   Nature Chemical Biology

Asymmetry of GPCR oligomers supports their functional relevance

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Exploring a role for heteromerization in GPCR signalling specificity

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Rab11 Supports Amphetamine-Stimulated Norepinephrine Transporter Trafficking

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Novel therapeutic targets for hypertension

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Allostery at G Protein-Coupled Receptor Homo- and Heteromers: Uncharted Pharmacological Landscapes

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Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation

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Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules

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GPCR Dimers Fall Apart

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Instability of a Class A G Protein-Coupled Receptor Oligomer Interface

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Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation

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Dopamine D2 receptors form higher order oligomers at physiological expression levels

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Identification of a serotonin/glutamate receptor complex implicated in psychosis

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G protein-coupled receptor dimers: Functional consequences, disease states and drug targets

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