Characterization of PF-6142, a Novel, Non-Catecholamine Dopamine Receptor D1 Agonist, in Murine and Nonhuman Primate Models of Dopaminergic Activation

D1 Agonist Improved Movement of Parkinsonian Nonhuman Primates with Limited Dyskinesia Side Effects

(2020) Damon Young et al.   ACS Chemical Neuroscience

Activation of D1 receptors affects human reactivity and flexibility to valued cues

(2020) Alexander Soutschek et al.   NEUROPSYCHOPHARMACOLOGY

A novel dopamine D1 receptor agonist excites delay-dependent working memory-related neuronal firing in primate dorsolateral prefrontal cortex

(2019) Min Wang et al.   NEUROPHARMACOLOGY

Dopaminergic D1 receptor stimulation affects effort and risk preferences

(2019) Alexander Soutschek et al.   BIOLOGICAL PSYCHIATRY

Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor

(2018) David L. Gray et al.   Nature Communications

Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization

(2018) Jennifer E. Davoren et al.   JOURNAL OF MEDICINAL CHEMISTRY

A proof-of-concept, randomized controlled trial of DAR-0100A, a dopamine-1 receptor agonist, for cognitive enhancement in schizophrenia

(2016) Ragy R Girgis et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Effects of the D1 Dopamine Receptor Agonist Dihydrexidine (DAR-0100A) on Working Memory in Schizotypal Personality Disorder

(2014) Daniel R Rosell et al.   NEUROPSYCHOPHARMACOLOGY

Dopamine D1 sensitivity in the prefrontal cortex predicts general cognitive abilities and is modulated by working memory training

(2013) C. Wass et al.   LEARNING & MEMORY

D1 receptor agonist improves sleep–wake parameters in experimental parkinsonism

(2013) Carole Hyacinthe et al.   NEUROBIOLOGY OF DISEASE

Neurophysiological signals as potential translatable biomarkers for modulation of metabotropic glutamate 5 receptors

(2013) B.D. Harvey et al.   NEUROPHARMACOLOGY

Prefrontal dopamine and behavioral flexibility: shifting from an “inverted-U” toward a family of functions

(2013) Stan B. Floresco   Frontiers in Neuroscience

Functional Significance of Central D1 Receptors in Cognition: Beyond Working Memory

(2012) Hidehiko Takahashi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Interaction Between Family History of Alcoholism and Locus of Control in the Opioid Regulation of Impulsive Responding Under the Influence of Alcohol

(2011) Lee J. Altamirano et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Modulation of NMDA receptor function by inhibition of d-amino acid oxidase in rodent brain

(2011) Christine A. Strick et al.   NEUROPHARMACOLOGY

Preclinical assessment of an adjunctive treatment approach for cognitive impairment associated with schizophrenia using the alpha7 nicotinic acetylcholine receptor agonist WYE-103914/SEN34625

(2011) Karen L. Marquis et al.   PSYCHOPHARMACOLOGY

Role of Thalamic Projection in NMDA Receptor-Induced Disruption of Cortical Slow Oscillation and Short-Term Plasticity

(2011) Tamás Kiss et al.   Frontiers in Psychiatry

Amelioration of ketamine-induced working memory deficits by dopamine D1 receptor agonists

(2010) Brooke M. Roberts et al.   PSYCHOPHARMACOLOGY

The Dopamine Hypothesis of Schizophrenia: Version III--The Final Common Pathway

(2009) O. D. Howes et al.   SCHIZOPHRENIA BULLETIN

Dopamine D1receptor ligands: Where are we now and where are we going

(2008) Jing Zhang et al.   MEDICINAL RESEARCH REVIEWS