Astragalus mongholicus Bunge and Panax notoginseng (Burkill) F.H. Chen Formula for Renal Injury in Diabetic Nephropathy—In Vivo and In Vitro Evidence for Autophagy Regulation

Sanqi oral solution ameliorates renal damage and restores podocyte injury in experimental membranous nephropathy via suppression of NFκB

(2019) Ruimin Tian et al.   BIOMEDICINE & PHARMACOTHERAPY

PGRN acts as a novel regulator of mitochondrial homeostasis by facilitating mitophagy and mitochondrial biogenesis to prevent podocyte injury in diabetic nephropathy

(2019) Di Zhou et al.   Cell Death & Disease

Renoprotective effect of calycosin in high fat diet-fed/STZ injected rats: Effect on IL-33/ST2 signaling, oxidative stress and fibrosis suppression

(2019) Nehal M. Elsherbiny et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Neuroprotective Mechanisms of Calycosin Against Focal Cerebral Ischemia and Reperfusion Injury in Rats

(2018) Yong Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Nitro-Oxidative Stress Correlates with Se Tolerance of Astragalus Species

(2018) Zsuzsanna Kolbert et al.   PLANT AND CELL PHYSIOLOGY

Glomerular endothelial cells versus podocytes as the cellular target in diabetic nephropathy

(2018) Silvia Maestroni et al.   ACTA DIABETOLOGICA

Targeting inflammation in diabetic nephropathy: a tale of hope

(2018) Juan Antonio Moreno et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Celastrol antagonizes high glucose-evoked podocyte injury, inflammation and insulin resistance by restoring the HO-1-mediated autophagy pathway

(2018) Xiaojiang Zhan et al.   MOLECULAR IMMUNOLOGY

Compound Danshen Dripping Pill Inhibits Retina Cell Apoptosis in Diabetic Rats

(2018) Qian Zhang et al.   Frontiers in Physiology

FoxO1 Promotes Mitophagy in the Podocytes of Diabetic Male Mice via the PINK1/Parkin Pathway

(2017) Wen Li et al.   ENDOCRINOLOGY

Astragaloside IV from Astragalus membranaceus ameliorates renal interstitial fibrosis by inhibiting inflammation via TLR4/NF-кB in vivo and in vitro

(2017) Xiangjun Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Macrophage heme oxygenase-1-SIRT1-p53 axis regulates sterile inflammation in liver ischemia-reperfusion injury

(2017) Kojiro Nakamura et al.   JOURNAL OF HEPATOLOGY

Angiotensin-converting enzyme 2 amplification limited to the circulation does not protect mice from development of diabetic nephropathy

(2017) Jan Wysocki et al.   KIDNEY INTERNATIONAL

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Hybrid drug combination: Combination of ferulic acid and metformin as anti-diabetic therapy

(2017) Rakesh Nankar et al.   PHYTOMEDICINE

Amelioration of CCl 4 -induced liver injury in rats by selenizing Astragalus polysaccharides: Role of proinflammatory cytokines, oxidative stress and hepatic stellate cells

(2017) Mohammed Hamid et al.   RESEARCH IN VETERINARY SCIENCE

The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1

(2017) Li Xiao et al.   Redox Biology

Astragaloside IV ameliorates diabetic nephropathy by modulating the mitochondrial quality control network

(2017) Xinhui Liu et al.   PLoS One

Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis

(2016) Huiyan Li et al.   Autophagy

The Antioxidant Effects of Radix Astragali (Astragalus membranaceus and Related Species) in Protecting Tissues from Injury and Disease

(2016) Muhammad Shahzad et al.   CURRENT DRUG TARGETS

Inhibitory Effects of Astragaloside IV on Bleomycin-Induced Pulmonary Fibrosis in Rats Via Attenuation of Oxidative Stress and Inflammation

(2016) Wei-Na Yu et al.   INFLAMMATION

Melatonin attenuates traumatic brain injury-induced inflammation: a possible role for mitophagy

(2016) Chao Lin et al.   JOURNAL OF PINEAL RESEARCH

Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD

(2016) K. Yamamoto-Nonaka et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Challenging the dogma of mitochondrial reactive oxygen species overproduction in diabetic kidney disease

(2016) Melinda T. Coughlan et al.   KIDNEY INTERNATIONAL

Compounds from the pods of Astragalus armatus with antioxidant, anticholinesterase, antibacterial and phagocytic activities

(2016) Amira Labed et al.   PHARMACEUTICAL BIOLOGY

AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells

(2015) Stuti Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epidermal Growth Factor Receptor Inhibition Slows Progression of Diabetic Nephropathy in Association With a Decrease in Endoplasmic Reticulum Stress and an Increase in Autophagy

(2014) Ming-Zhi Zhang et al.   DIABETES

Hypertension Is a Major Contributor to 20-Hydroxyeicosatetraenoic Acid-Mediated Kidney Injury in Diabetic Nephropathy

(2014) M. H. Gangadhariah et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mitochondrial ROS deficiency and diabetic complications: AMP[K]-lifying the adaptation to hyperglycemia

(2013) Dwight A. Towler   JOURNAL OF CLINICAL INVESTIGATION

Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc

(2012) F. Bock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regional differences in clinical care among patients with type 1 diabetes in Brazil: Brazilian Type 1 Diabetes Study Group

(2012) Marília B Gomes et al.   Diabetology & Metabolic Syndrome

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

(2011) Markus Gödel et al.   JOURNAL OF CLINICAL INVESTIGATION

Hyperglycemia and Renin-Dependent Hypertension Synergize to Model Diabetic Nephropathy

(2011) B. R. Conway et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy

(2011) Juan F. Navarro-González et al.   Nature Reviews Nephrology

Prospective randomized controlled study of a Chinese herbal medicine compound Tangzu Yuyang Ointment for chronic diabetic foot ulcers: A preliminary report

(2010) Shufa Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hypolipidemic and antioxidant activities of Sanchi (Radix Notoginseng) in rats fed with a high fat diet

(2010) Wei Xia et al.   PHYTOMEDICINE

Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes

(2008) J. M. Forbes et al.   DIABETES

Effect of total flavonoid fraction of Astragalus complanatus R.Brown on angiotensin II-induced portal-vein contraction in hypertensive rats

(2008) B. Xue et al.   PHYTOMEDICINE