CTCF loss mediates unique DNA hypermethylation landscapes in human cancers

The ion channels and transporters gene expression profile indicates a shift in excitability and metabolisms during malignant progression of Follicular Lymphoma

(2019) Alberto Magi et al.   Scientific Reports

A high-resolution 3D epigenomic map reveals insights into the creation of the prostate cancer transcriptome

(2019) Suhn Kyong Rhie et al.   Nature Communications

Simultaneous E-cadherin and PLEKHA7 expression negatively affects E-cadherin/EGFR mediated ovarian cancer cell growth

(2018) Katia Rea et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

CTCF and Cohesin in Genome Folding and Transcriptional Gene Regulation

(2016) Matthias Merkenschlager et al.   Annual Review of Genomics and Human Genetics

The Molecular Taxonomy of Primary Prostate Cancer

(2015) Adam Abeshouse et al.   CELL

Insulator dysfunction and oncogene activation in IDH mutant gliomas

(2015) William A. Flavahan et al.   NATURE

CTCF/cohesin-binding sites are frequently mutated in cancer

(2015) Riku Katainen et al.   NATURE GENETICS

Role of DNA Methylation in Modulating Transcription Factor Occupancy

(2015) Matthew T. Maurano et al.   Cell Reports

Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture

(2015) Matteo Vietri Rudan et al.   Cell Reports

The Expression of the Zonula Adhaerens Protein PLEKHA7 Is Strongly Decreased in High Grade Ductal and Lobular Breast Carcinomas

(2015) Jean-Christophe Tille et al.   PLoS One

Methylation Profiling Defines an Extensive Field Defect in Histologically Normal Prostate Tissues Associated with Prostate Cancer

(2015) Bing Yang et al.   NEOPLASIA

A Novel Pathway Links Oxidative Stress to Loss of Insulin Growth Factor-2 (IGF2) Imprinting through NF-κB Activation

(2014) Bing Yang et al.   PLoS One

CTCF Haploinsufficiency Destabilizes DNA Methylation and Predisposes to Cancer

(2014) Christopher J. Kemp et al.   Cell Reports

Frequent Disruption of Chromodomain Helicase DNA-Binding Protein 8 (CHD8) and Functionally Associated Chromatin Regulators in Prostate Cancer

(2014) Nathan A. Damaschke et al.   NEOPLASIA

Genome-Wide Methylation Analysis of Prostate Tissues Reveals Global Methylation Patterns of Prostate Cancer

(2013) Jian-Hua Luo et al.   AMERICAN JOURNAL OF PATHOLOGY

Pyrosequencing for the rapid and efficient quantification of allele-specific expression

(2013) Bing Yang et al.   Epigenetics

Genome-wide and parental allele-specific analysis of CTCF and cohesin DNA binding in mouse brain reveals a tissue-specific binding pattern and an association with imprinted differentially methylated regions

(2013) A. R. Prickett et al.   GENOME RESEARCH

Epigenetic susceptibility factors for prostate cancer with aging

(2013) N. A. Damaschke et al.   PROSTATE

DNA Methylation Alterations Exhibit Intraindividual Stability and Interindividual Heterogeneity in Prostate Cancer Metastases

(2013) M. J. Aryee et al.   Science Translational Medicine

Standardization and quality controls for the methylated DNA immunoprecipitation technique

(2012) Sofia Lisanti et al.   Epigenetics

Widespread plasticity in CTCF occupancy linked to DNA methylation

(2012) H. Wang et al.   GENOME RESEARCH

The mutational landscape of lethal castration-resistant prostate cancer

(2012) Catherine S. Grasso et al.   NATURE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Comprehensive Identification and Annotation of Cell Type-Specific and Ubiquitous CTCF-Binding Sites in the Human Genome

(2012) Hebing Chen et al.   PLoS One

The tumor suppressor role of CTCF

(2011) Francesco Paolo Fiorentino et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CTCF is a DNA methylation-sensitive positive regulator of the INK/ARF locus

(2010) Carmen Rodriguez et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome

(2010) Stephen Ho Kin Chan et al.   INTERNATIONAL JOURNAL OF CANCER

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Epigenetic regulation of the human p53 gene promoter by the CTCF transcription factor in transformed cell lines

(2010) E Soto-Reyes et al.   ONCOGENE

The proteins ARVCF and p0071 in renal cell carcinomas and their potential use in the diagnosis of renal tumours

(2009) Britta Walter et al.   HISTOPATHOLOGY

Epigenetic Silencing of the p16INK4a Tumor Suppressor Is Associated with Loss of CTCF Binding and a Chromatin Boundary

(2009) Michael Witcher et al.   MOLECULAR CELL

Aging and Cancer-Related Loss of Insulin-like Growth Factor 2 Imprinting in the Mouse and Human Prostate

(2008) V. X. Fu et al.   CANCER RESEARCH

Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms

(2008) Vania Parelho et al.   CELL

Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators

(2008) William Stedman et al.   EMBO JOURNAL

Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains

(2008) S. Cuddapah et al.   GENOME RESEARCH

CCCTC-binding Factor Activates PARP-1 Affecting DNA Methylation Machinery

(2008) Tiziana Guastafierro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cohesin mediates transcriptional insulation by CCCTC-binding factor

(2008) Kerstin S. Wendt et al.   NATURE

CTCF physically links cohesin to chromatin

(2008) E. D. Rubio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA