Simultaneous E-cadherin and PLEKHA7 expression negatively affects E-cadherin/EGFR mediated ovarian cancer cell growth

A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFα-TGFα-EGFR

(2017) T-S Lau et al.   ONCOGENE

Cadherin composition and multicellular aggregate invasion in organotypic models of epithelial ovarian cancer intraperitoneal metastasis

(2017) Y Klymenko et al.   ONCOGENE

Heterogeneous Cadherin Expression and Multicellular Aggregate Dynamics in Ovarian Cancer Dissemination

(2017) Yuliya Klymenko et al.   NEOPLASIA

Complex Determinants of Epithelial: Mesenchymal Phenotypic Plasticity in Ovarian Cancer

(2017) Yuliya Klymenko et al.   Cancers

Crystal Structure of Human E-Cadherin-EC1EC2 in Complex with a Peptidomimetic Competitive Inhibitor of Cadherin Homophilic Interaction

(2016) Valentina Nardone et al.   JOURNAL OF MEDICINAL CHEMISTRY

In vivo tumor growth of high-grade serous ovarian cancer cell lines

(2015) Anirban K. Mitra et al.   GYNECOLOGIC ONCOLOGY

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Distinct E-cadherin-based complexes regulate cell behaviour through miRNA processing or Src and p120 catenin activity

(2015) Antonis Kourtidis et al.   NATURE CELL BIOLOGY

Computational design of novel peptidomimetic inhibitors of cadherin homophilic interactions

(2015) Fabio Doro et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy

(2015) Evelyn Despierre et al.   Targeted Oncology

Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression

(2015) Xin Ye et al.   TRENDS IN CELL BIOLOGY

Contributions of the Epidermal Growth Factor Receptor to Acquisition of Platinum Resistance in Ovarian Cancer Cells

(2015) Michaela L. Granados et al.   PLoS One

The Expression of the Zonula Adhaerens Protein PLEKHA7 Is Strongly Decreased in High Grade Ductal and Lobular Breast Carcinomas

(2015) Jean-Christophe Tille et al.   PLoS One

Variant HNF1 Modulates Epithelial Plasticity of Normal and Transformed Ovary Cells

(2015) Antonella Tomassetti et al.   NEOPLASIA

Comprehensive gene expression meta-analysis of head and neck squamous cell carcinoma microarray data defines a robust survival predictor

(2014) L. De Cecco et al.   ANNALS OF ONCOLOGY

Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling

(2014) Masatoshi Takeichi   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epithelial–mesenchymal status renders differential responses to cisplatin in ovarian cancer

(2014) Q H Miow et al.   ONCOGENE

Construction and characteristics of an E-cadherin-related three-dimensional suspension growth model of ovarian cancer

(2014) Shan Xu et al.   Scientific Reports

An IL6-correlated signature in serous epithelial ovarian cancer associates with growth factor response

(2013) Patrizia Pinciroli et al.   BMC GENOMICS

Ovarian surface epithelium as a source of ovarian cancers: Unwarranted speculation or evidence-based hypothesis?

(2013) Nelly Auersperg   GYNECOLOGIC ONCOLOGY

Binding between the Junctional Proteins Afadin and PLEKHA7 and Implication in the Formation of Adherens Junction in Epithelial Cells

(2013) Souichi Kurita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Randomized Phase III Study of Erlotinib Versus Observation in Patients With No Evidence of Disease Progression After First-Line Platin-Based Chemotherapy for Ovarian Carcinoma: A European Organisation for Research and Treatment of Cancer-Gynaecological Cancer Group, and Gynecologic Cancer Intergroup Study

(2013) Ignace B. Vergote et al.   JOURNAL OF CLINICAL ONCOLOGY

EGFR/MEK/ERK/CDK5-dependent integrin-independent FAK phosphorylated on serine 732 contributes to microtubule depolymerization and mitosis in tumor cells

(2013) K Rea et al.   Cell Death & Disease

The many faces and functions of β-catenin

(2012) Tomas Valenta et al.   EMBO JOURNAL

Isolation and Characterization of Tumor Cells from the Ascites of Ovarian Cancer Patients: Molecular Phenotype of Chemoresistant Ovarian Tumors

(2012) Ardian Latifi et al.   PLoS One

miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response

(2011) Bogdan Mateescu et al.   NATURE MEDICINE

Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer

(2011) C Alberti et al.   ONCOGENE

Ovarian Cancer Development and Metastasis

(2010) Ernst Lengyel   AMERICAN JOURNAL OF PATHOLOGY

The Origin of Ovarian Carcinomas

(2010) Nelly Auersperg   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Hydrogen Peroxide Mediates EGF-Induced Down-Regulation of E-Cadherin Expression via p38 MAPK and Snail in Human Ovarian Cancer Cells

(2010) Jung-Chien Cheng et al.   MOLECULAR ENDOCRINOLOGY

E-cadherin directly contributes to PI3K/AKT activation by engaging the PI3K-p85 regulatory subunit to adherens junctions of ovarian carcinoma cells

(2009) G De Santis et al.   ONCOGENE

Matrix Metalloproteinase 9 Is a Mediator of Epidermal Growth Factor-Dependent E-Cadherin Loss in Ovarian Carcinoma Cells

(2008) K. D. Cowden Dahl et al.   CANCER RESEARCH

Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome

(2008) R. W. Tothill et al.   CLINICAL CANCER RESEARCH