The αβTCR mechanosensor exploits dynamic ectodomain allostery to optimize its ligand recognition site
出版年份 2020 全文链接
标题
The αβTCR mechanosensor exploits dynamic ectodomain allostery to optimize its ligand recognition site
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume -, Issue -, Pages 202005899
出版商
Proceedings of the National Academy of Sciences
发表日期
2020-08-14
DOI
10.1073/pnas.2005899117
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition
- (2019) Peng Wu et al. MOLECULAR CELL
- NMR: an essential structural tool for integrative studies of T cell development, pMHC ligand recognition and TCR mechanobiology
- (2019) Robert J. Mallis et al. JOURNAL OF BIOMOLECULAR NMR
- Structural basis of assembly of the human T cell receptor–CD3 complex
- (2019) De Dong et al. NATURE
- Mechanosensing through immunoreceptors
- (2019) Cheng Zhu et al. NATURE IMMUNOLOGY
- MHC binding affects the dynamics of different T-cell receptors in different ways
- (2019) Bernhard Knapp et al. PLoS Computational Biology
- The structural basis of T-cell receptor (TCR) activation: An enduring enigma
- (2019) Roy A. Mariuzza et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Monomeric TCRs drive T cell antigen recognition
- (2018) Mario Brameshuber et al. NATURE IMMUNOLOGY
- αβ T Cell Receptor Mechanosensing Forces out Serial Engagement
- (2018) Yinnian Feng et al. TRENDS IN IMMUNOLOGY
- Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding
- (2018) Leah V. Sibener et al. CELL
- Peptide–MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites
- (2018) Sneha Rangarajan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The T Cell Antigen Receptor α Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations
- (2018) Kristine N. Brazin et al. IMMUNITY
- Mechanosensing drives acuity ofαβT-cell recognition
- (2017) Yinnian Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity
- (2017) Vincent C. Luca et al. SCIENCE
- Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing
- (2016) Roshni Basu et al. CELL
- Pre-T Cell Receptors (Pre-TCRs) Leverage Vβ Complementarity Determining Regions (CDRs) and Hydrophobic Patch in Mechanosensing Thymic Self-ligands
- (2016) Dibyendu Kumar Das et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- T cell activation requires force generation
- (2016) Kenneth H. Hu et al. JOURNAL OF CELL BIOLOGY
- DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity
- (2016) Yang Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Elastic Energy Partitioning in DNA Deformation and Binding to Proteins
- (2015) Xiaojing Teng et al. ACS Nano
- Early T Cell Activation: Integrating Biochemical, Structural, and Biophysical Cues
- (2015) Bernard Malissen et al. Annual Review of Immunology
- T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules
- (2015) Jamie Rossjohn et al. Annual Review of Immunology
- Current status and future challenges in T-cell receptor/peptide/MHC molecular dynamics simulations
- (2015) B. Knapp et al. BRIEFINGS IN BIOINFORMATICS
- Cytoskeletal forces during signaling activation in Jurkat T-cells
- (2015) King Lam Hui et al. MOLECULAR BIOLOGY OF THE CELL
- Pre-TCR ligand binding impacts thymocyte development before αβTCR expression
- (2015) Robert J. Mallis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime
- (2015) Dibyendu Kumar Das et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Features of the αβTCR Mechanotransduction Apparatus That Promote pMHC Discrimination
- (2015) Kristine N. Brazin et al. Frontiers in Immunology
- Accumulation of Dynamic Catch Bonds between TCR and Agonist Peptide-MHC Triggers T Cell Signaling
- (2014) Baoyu Liu et al. CELL
- Tracking migration during human T cell development
- (2014) Joanna Halkias et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The ensemble nature of allostery
- (2014) Hesam N. Motlagh et al. NATURE
- Large Scale Characterization of the LC13 TCR and HLA-B8 Structural Landscape in Reaction to 172 Altered Peptide Ligands: A Molecular Dynamics Simulation Study
- (2014) Bernhard Knapp et al. PLoS Computational Biology
- A Single Peptide-Major Histocompatibility Complex Ligand Triggers Digital Cytokine Secretion in CD4+ T Cells
- (2013) Jun Huang et al. IMMUNITY
- β-Selection-Induced Proliferation Is Required for αβ T Cell Differentiation
- (2012) Taras Kreslavsky et al. IMMUNITY
- The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function
- (2012) Jia-huai Wang et al. IMMUNOLOGICAL REVIEWS
- Mechanisms of T Cell Development and Transformation
- (2011) Ute Koch et al. Annual Review of Cell and Developmental Biology
- Force Generation upon T Cell Receptor Engagement
- (2011) Julien Husson et al. PLoS One
- Structural Basis for Mechanical Force Regulation of the Adhesin FimH via Finger Trap-like β Sheet Twisting
- (2010) Isolde Le Trong et al. CELL
- Cutting Edge: Mechanical Forces Acting on T Cells Immobilized via the TCR Complex Can Trigger TCR Signaling
- (2010) Y. C. Li et al. JOURNAL OF IMMUNOLOGY
- The catch bond mechanism between von Willebrand factor and platelet surface receptors investigated by molecular dynamics simulations
- (2010) Gianluca Interlandi et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- The αβ T Cell Receptor Is an Anisotropic Mechanosensor
- (2009) Sun Taek Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CHARMM: The biomolecular simulation program
- (2009) B. R. Brooks et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Biophysics of Catch Bonds
- (2008) Wendy E. Thomas et al. Annual Review of Biophysics
- The Structural Dynamics and Energetics of an Immunodominant T Cell Receptor Are Programmed by Its Vβ Domain
- (2008) Jeffrey Ishizuka et al. IMMUNITY
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