Telomerase reverse transcriptase ( TERT ) promoter mutation correlated with intratumoral heterogeneity in hepatocellular carcinoma

Keratin 19‐expressing hepatocellular carcinoma and small‐duct type intrahepatic cholangiocarcinoma show a similar post‐operative clinical course but have distinct genetic features

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Novel approaches for molecular targeted therapy against hepatocellular carcinoma

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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification

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Immunohistochemical molecular analysis indicates hepatocellular carcinoma subgroups that reflect tumor aggressiveness

(2016) Hanako Tsujikawa et al.   HUMAN PATHOLOGY

Understanding TERT Promoter Mutations: A Common Path to Immortality

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Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation

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Genetic Landscape and Biomarkers of Hepatocellular Carcinoma

(2015) Jessica Zucman-Rossi et al.   GASTROENTEROLOGY

Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features

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Intratumor Heterogeneity in Hepatocellular Carcinoma

(2014) J. Friemel et al.   CLINICAL CANCER RESEARCH

Telomerase reverse transcriptase promoter mutation is an early somatic genetic alteration in the transformation of premalignant nodules in hepatocellular carcinoma on cirrhosis

(2014) Jean Charles Nault et al.   HEPATOLOGY

TERT promoter mutations: Gatekeeper and driver of hepatocellular carcinoma

(2014) Roser Pinyol et al.   JOURNAL OF HEPATOLOGY

Pathogenesis and prevention of hepatitis C virus-induced hepatocellular carcinoma

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Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

(2014) Yasushi Totoki et al.   NATURE GENETICS

Frequency of TERT promoter mutations in primary tumors of the liver

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TERT promoter mutation in resectable hepatocellular carcinomas: A strong association with hepatitis C infection and absence of hepatitis B infection

(2014) Yu-Ling Chen et al.   International Journal of Surgery

TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine

(2013) I. Kinde et al.   CANCER RESEARCH

Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

(2013) Z. Kan et al.   GENOME RESEARCH

Mutations of the TERT promoter are common in basal cell carcinoma and squamous cell carcinoma

(2013) Glynis A Scott et al.   MODERN PATHOLOGY

The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas

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TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

(2013) P. J. Killela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TERT Promoter Mutations in Familial and Sporadic Melanoma

(2013) S. Horn et al.   SCIENCE

Highly Recurrent TERT Promoter Mutations in Human Melanoma

(2013) F. W. Huang et al.   SCIENCE

High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions

(2013) Jean Charles Nault et al.   Nature Communications

Sal-like protein 4 (SALL4), a stem cell biomarker in liver cancers

(2012) Tsunekazu Oikawa et al.   HEPATOLOGY

Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma

(2012) Wing-Kin Sung et al.   NATURE GENETICS

Human hepatocellular carcinomas with “Stemness”-related marker expression: keratin 19 expression and a poor prognosis

(2011) Haeryoung Kim et al.   HEPATOLOGY

Molecular Diagnosis of Multistage Hepatocarcinogenesis

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Molecular Classification and Novel Targets in Hepatocellular Carcinoma: Recent Advancements

(2010) Yujin Hoshida et al.   SEMINARS IN LIVER DISEASE

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

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