Curcumin analog WZ35 induced cell death via ROS-dependent ER stress and G2/M cell cycle arrest in human prostate cancer cells

Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivo

(2015) Chunlai Zeng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Evaluation of a curcumin analog as an anti-cancer agent inducing ER stress-mediated apoptosis in non-small cell lung cancer cells

(2013) Zhiguo Liu et al.   BMC CANCER

B19, a Novel Monocarbonyl Analogue of Curcumin, Induces Human Ovarian Cancer Cell Apoptosis via Activation of Endoplasmic Reticulum Stress and the Autophagy Signaling Pathway

(2013) Wanglei Qu et al.   International Journal of Biological Sciences

Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress

(2012) K Ketola et al.   BRITISH JOURNAL OF CANCER

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

(2012) T Verfaillie et al.   CELL DEATH AND DIFFERENTIATION

A novel synthetic protoapigenone analogue, WYC02-9, induces DNA damage and apoptosis in DU145 prostate cancer cells through generation of reactive oxygen species

(2011) Huei-Mei Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

A synthetic compound, 1,5-bis(2-methoxyphenyl)penta- 1,4-dien-3-one (B63), induces apoptosis and activates endoplasmic reticulum stress in non-small cell lung cancer cells

(2011) Jian Xiao et al.   INTERNATIONAL JOURNAL OF CANCER

Induction of the unfolded protein response by cigarette smoke is primarily an activating transcription factor 4-C/EBP homologous protein mediated process

(2011) Geraghty et al.   International Journal of Chronic Obstructive Pulmonary Disease

Synthesis of mono-carbonyl analogues of curcumin and their effects on inhibition of cytokine release in LPS-stimulated RAW 264.7 macrophages

(2010) Chengguang Zhao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Targeting ER stress induced apoptosis and inflammation in cancer

(2010) Tom Verfaillie et al.   CANCER LETTERS

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox Regulation in Cancer: A Double-edged Sword with Therapeutic Potential

(2010) Asha Acharya et al.   Oxidative Medicine and Cellular Longevity

Combining the Endoplasmic Reticulum Stress-Inducing Agents Bortezomib and Fenretinide as a Novel Therapeutic Strategy for Metastatic Melanoma

(2009) D. S. Hill et al.   CLINICAL CANCER RESEARCH

Chemopreventive potential of curcumin in prostate cancer

(2009) Marie-Hélène Teiten et al.   Genes and Nutrition

Regulation of Endoplasmic Reticulum Stress-induced Cell Death by ATF4 in Neuroectodermal Tumor Cells

(2009) Jane L. Armstrong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

(2008) N. Dhillon et al.   CLINICAL CANCER RESEARCH

Synthesis, crystal structure and anti-inflammatory properties of curcumin analogues

(2008) Guang Liang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

(2008) J. D. Malhotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular death platform steps-in: Targeting prostate tumors via endoplasmic reticulum (ER) apoptosis

(2008) Steven R. Schwarze et al.   PROSTATE

Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells

(2007) Clay C.C. Wang et al.   CANCER LETTERS