Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress

Oxidative stress-related proteins in a Conn’s adenoma tissue. Relevance for aldosterone’s prooxidative and proinflammatory activity

(2014) L. A. Calò et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Effects of Salinomycin on Cancer Stem Cell in Human Lung Adenocarcinoma A549 Cells

(2012) Yi Wang   Medicinal Chemistry

Arachidonic Acid Pathway Members PLA2G7, HPGD, EPHX2, and CYP4F8 Identified as Putative Novel Therapeutic Targets in Prostate Cancer

(2011) Paula Vainio et al.   AMERICAN JOURNAL OF PATHOLOGY

Salinomycin Selectively Targets ‘CD133+’ Cell Subpopulations and Decreases Malignant Traits in Colorectal Cancer Lines

(2011) Tao-Tao Dong et al.   ANNALS OF SURGICAL ONCOLOGY

CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth

(2011) Takatsugu Ishimoto et al.   CANCER CELL

Therapeutics formulated to target cancer stem cells: Is it in our future?

(2011) Stephanie Clayton et al.   Cancer Cell International

Regulation of reactive oxygen species in stem cells and cancer stem cells

(2011) Chiharu I. Kobayashi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling

(2011) Vinagolu K. Rajasekhar et al.   Nature Communications

Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells

(2010) Dominik Fuchs et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein

(2010) Ju-Hwa Kim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF- B Pathway and Generation of Reactive Oxygen Species

(2010) Y. Jin et al.   CANCER RESEARCH

Activation of NF-κB by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4

(2010) Jianghua Wang et al.   CANCER RESEARCH

High Aldehyde Dehydrogenase Activity Identifies Tumor-Initiating and Metastasis-Initiating Cells in Human Prostate Cancer

(2010) Christel van den Hoogen et al.   CANCER RESEARCH

Monensin Is a Potent Inducer of Oxidative Stress and Inhibitor of Androgen Signaling Leading to Apoptosis in Prostate Cancer Cells

(2010) K. Ketola et al.   MOLECULAR CANCER THERAPEUTICS

Aldosterone induces oxidative stress, oxidative DNA damage and NF-κB-activation in kidney tubule cells

(2010) Nina Queisser et al.   MOLECULAR CARCINOGENESIS

Progesterone induces adult mammary stem cell expansion

(2010) Purna A. Joshi et al.   NATURE

Redox Regulation in Cancer: A Double-edged Sword with Therapeutic Potential

(2010) Asha Acharya et al.   Oxidative Medicine and Cellular Longevity

β-TrCP Inhibition Reduces Prostate Cancer Cell Growth via Upregulation of the Aryl Hydrocarbon Receptor

(2010) Udi Gluschnaider et al.   PLoS One

Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells

(2009) Dominik Fuchs et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative stress in prostate cancer

(2009) Lakshmipathi Khandrika et al.   CANCER LETTERS

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature

(2009) George J. Klarmann et al.   CLINICAL & EXPERIMENTAL METASTASIS

Nuclear Factor- B-Mediated Transforming Growth Factor- -Induced Expression of Vimentin Is an Independent Predictor of Biochemical Recurrence after Radical Prostatectomy

(2009) Q. Zhang et al.   CLINICAL CANCER RESEARCH

High-Throughput Cell-Based Screening of 4910 Known Drugs and Drug-like Small Molecules Identifies Disulfiram as an Inhibitor of Prostate Cancer Cell Growth

(2009) K. Iljin et al.   CLINICAL CANCER RESEARCH

ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients’ outcome

(2009) Ting Li et al.   LABORATORY INVESTIGATION

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Oxygen Toxicity and Reactive Oxygen Species: The Devil Is in the Details

(2009) Richard L Auten et al.   PEDIATRIC RESEARCH

Molecular Signatures of Prostate Stem Cells Reveal Novel Signaling Pathways and Provide Insights into Prostate Cancer

(2009) Roy Blum et al.   PLoS One

High Aldehyde Dehydrogenase Activity: A Novel Functional Marker of Murine Prostate Stem/Progenitor Cells

(2009) Patricia E. Burger et al.   STEM CELLS

The Nuclear Factor- B Pathway Controls the Progression of Prostate Cancer to Androgen-Independent Growth

(2008) R. J. Jin et al.   CANCER RESEARCH

NF-κB Signaling Pathway and Its Therapeutic Implications in Human Diseases

(2008) Fazlul H. Sarkar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Aldehyde Dehydrogenase as a Marker for Stem Cells

(2008) Jan Moreb   Current Stem Cell Research & Therapy

Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions

(2008) Richard Birnie et al.   GENOME BIOLOGY