Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer

Engineered Protein Scaffolds as Next-Generation Therapeutics

(2020) Michaela Gebauer et al.   Annual Review of Pharmacology and Toxicology

The complex formed between a synthetic RNA aptamer and the transcription repressor TetR is a structural and functional twin of the operator DNA–TetR regulator complex

(2020) Florian C Grau et al.   NUCLEIC ACIDS RESEARCH

Updates on Aptamer Research

(2019) Ali et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PSMA-Targeted Radiopharmaceuticals for Imaging and Therapy

(2019) Hans-Jürgen Wester et al.   SEMINARS IN NUCLEAR MEDICINE

Intracellular Delivery of Glucose Oxidase for Enhanced Cytotoxicity toward PSMA‐Expressing Prostate Cancer Cells

(2019) Nicholas Flynn et al.   MACROMOLECULAR BIOSCIENCE

IsRNA: An Iterative Simulated Reference State Approach to Modeling Correlated Interactions in RNA Folding

(2018) Dong Zhang et al.   Journal of Chemical Theory and Computation

Targeting prostate cancer: Prostate-specific membrane antigen based diagnosis and therapy

(2018) Till Wüstemann et al.   MEDICINAL RESEARCH REVIEWS

Inhibitor–GCPII Interaction: Selective and Robust System for Targeting Cancer Cells with Structurally Diverse Nanoparticles

(2018) Jitka Neburkova et al.   MOLECULAR PHARMACEUTICS

Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass

(2018) Ruwan Gunaratne et al.   NATURE BIOTECHNOLOGY

RNApdbee 2.0: multifunctional tool for RNA structure annotation

(2018) Tomasz Zok et al.   NUCLEIC ACIDS RESEARCH

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Structure of an RNA Aptamer that Can Inhibit HIV-1 by Blocking Rev-Cognate RNA (RRE) Binding and Rev-Rev Association

(2018) Altaira D. Dearborn et al.   STRUCTURE

2-Aminoadipic Acid–C(O)–Glutamate Based Prostate-Specific Membrane Antigen Ligands for Potential Use as Theranostics

(2018) Ryo Nakajima et al.   ACS Medicinal Chemistry Letters

Expression of Prostate-Specific Membrane Antigen (PSMA) on Biopsies Is an Independent Risk Stratifier of Prostate Cancer Patients at Time of Initial Diagnosis

(2018) Marie Christine Hupe et al.   Frontiers in Oncology

Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors

(2017) Charalambos Kaittanis et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Novel Monoclonal Antibodies Recognizing Human Prostate-Specific Membrane Antigen (PSMA) as Research and Theranostic Tools

(2017) Zora Nováková et al.   PROSTATE

Mouse glutamate carboxypeptidase II (GCPII) has a similar enzyme activity and inhibition profile but a different tissue distribution to human GCPII

(2017) Tomáš Knedlík et al.   FEBS Open Bio

Comparison of human glutamate carboxypeptidases II and III reveals their divergent substrate specificities

(2016) Michal Navrátil et al.   FEBS Journal

Emerging applications of riboswitches – from antibacterial targets to molecular tools

(2016) Piotr Machtel et al.   JOURNAL OF APPLIED GENETICS

Aptamers as targeted therapeutics: current potential and challenges

(2016) Jiehua Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Selection and characterization of Anticalins targeting human prostate-specific membrane antigen (PSMA)

(2016) Cyril Barinka et al.   PROTEIN ENGINEERING DESIGN & SELECTION

SimRNA: a coarse-grained method for RNA folding simulations and 3D structure prediction

(2015) Michal J. Boniecki et al.   NUCLEIC ACIDS RESEARCH

Aptamers: Active Targeting Ligands for Cancer Diagnosis and Therapy

(2015) Xu Wu et al.   Theranostics

Indium 111-labeled J591 anti-PSMA antibody for vascular targeted imaging in progressive solid tumors

(2015) Neeta Pandit-Taskar et al.   EJNMMI Research

RNA aptamer-conjugated liposome as an efficient anticancer drug delivery vehicle targeting cancer cells in vivo

(2014) Si Eun Baek et al.   JOURNAL OF CONTROLLED RELEASE

Development of Targeted Near-Infrared Imaging Agents for Prostate Cancer

(2014) X. Wang et al.   MOLECULAR CANCER THERAPEUTICS

Targeted Inhibition of Prostate Cancer Metastases with an RNA Aptamer to Prostate-specific Membrane Antigen

(2014) Justin P Dassie et al.   MOLECULAR THERAPY

Vfold: A Web Server for RNA Structure and Folding Thermodynamics Prediction

(2014) Xiaojun Xu et al.   PLoS One

Comparative analysis of monoclonal antibodies against prostate-specific membrane antigen (PSMA)

(2014) J. Tykvart et al.   PROSTATE

EAU Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent—Update 2013

(2013) Axel Heidenreich et al.   EUROPEAN UROLOGY

Halogen Interactions in Protein–Ligand Complexes: Implications of Halogen Bonding for Rational Drug Design

(2013) Suman Sirimulla et al.   Journal of Chemical Information and Modeling

RNAstructure: web servers for RNA secondary structure prediction and analysis

(2013) Stanislav Bellaousov et al.   NUCLEIC ACIDS RESEARCH

RCrane: semi-automated RNA model building

(2012) Kevin S. Keating et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology

(2012) Rainer Wilcken et al.   JOURNAL OF MEDICINAL CHEMISTRY

Aptamer in Bioanalytical Applications

(2011) Anton B. Iliuk et al.   ANALYTICAL CHEMISTRY

Efficient and versatile one-step affinity purification of in vivo biotinylated proteins: Expression, characterization and structure analysis of recombinant human glutamate carboxypeptidase II

(2011) J. Tykvart et al.   PROTEIN EXPRESSION AND PURIFICATION

Rational Truncation of an RNA Aptamer to Prostate-Specific Membrane Antigen Using Computational Structural Modeling

(2011) William M. Rockey et al.   Nucleic Acid Therapeutics

A Drug-Loaded Aptamer−Gold Nanoparticle Bioconjugate for Combined CT Imaging and Therapy of Prostate Cancer

(2010) Dongkyu Kim et al.   ACS Nano

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Ten-Year Outcomes: The Clinical Utility of Single Photon Emission Computed Tomography/Computed Tomography Capromab Pendetide (Prostascint) in a Cohort Diagnosed With Localized Prostate Cancer

(2010) Rodney J. Ellis et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Atomic accuracy in predicting and designing noncanonical RNA structure

(2010) Rhiju Das et al.   NATURE METHODS

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

Conformational plasticity of RNA for target recognition as revealed by the 2.15 Å crystal structure of a human IgG–aptamer complex

(2010) Yusuke Nomura et al.   NUCLEIC ACIDS RESEARCH

Implications of the HIV-1 Rev dimer structure at 3.2 A resolution for multimeric binding to the Rev response element

(2010) M. A. DiMattia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III

(2009) Klara Hlouchova et al.   FEBS Journal

xia2: an expert system for macromolecular crystallography data reduction

(2009) G. Winter   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Iterative-build OMIT maps: map improvement by iterative model building and refinement without model bias

(2008) Thomas C. Terwilliger et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Basis of Interactions between Human Glutamate Carboxypeptidase II and Its Substrate Analogs

(2008) Cyril Barinka et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structure of an RNA aptamer bound to thrombin

(2008) S. B. Long et al.   RNA