Emerging applications of riboswitches – from antibacterial targets to molecular tools

Mn 2+ -Sensing Mechanisms of yybP-ykoY Orphan Riboswitches

(2015) Ian R. Price et al.   MOLECULAR CELL

Bacterial Riboswitches Cooperatively Bind Ni 2+ or Co 2+ Ions and Control Expression of Heavy Metal Transporters

(2015) Kazuhiro Furukawa et al.   MOLECULAR CELL

Themes and variations in riboswitch structure and function

(2014) Alla Peselis et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Artificial riboswitches for gene expression and replication control of DNA and RNA viruses

(2014) Patrick Ketzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Decade of Riboswitches

(2013) Alexander Serganov et al.   CELL

The promise of riboswitches as potential antibacterial drug targets

(2013) Christina E. Lünse et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Three-state mechanism couples ligand and temperature sensing in riboswitches

(2013) Anke Reining et al.   NATURE

Microbial Biosensors: Engineered Microorganisms as the Sensing Machinery

(2013) Miso Park et al.   SENSORS

Synthetic RNA devices to expedite the evolution of metabolite-producing microbes

(2013) Jina Yang et al.   Nature Communications

Identification of Ligand Analogues that Control c-di-GMP Riboswitches

(2012) Kazuhiro Furukawa et al.   ACS Chemical Biology

Fluoride enhances the activity of fungicides that destabilize cell membranes

(2012) Sanshu Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Experimental treatment of Staphylococcus aureus bovine intramammary infection using a guanine riboswitch ligand analog

(2012) C. Ster et al.   JOURNAL OF DAIRY SCIENCE

Endo-S-c-di-GMP Analogues-Polymorphism and Binding Studies with Class I Riboswitch

(2012) Jie Zhou et al.   MOLECULES

The prokaryote messenger c-di-GMP triggers stalk cell differentiation in Dictyostelium

(2012) Zhi-hui Chen et al.   NATURE

A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis

(2012) Danielle Biscaro Pedrolli et al.   NUCLEIC ACIDS RESEARCH

A Riboswitch-Based Inducible Gene Expression System for Mycobacteria

(2012) Jessica C. Seeliger et al.   PLoS One

Dual-acting riboswitch control of translation initiation and mRNA decay

(2012) M.-P. Caron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Riboswitch control of Rho-dependent transcription termination

(2012) K. Hollands et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carba-sugars Activate the glmS-Riboswitch ofStaphylococcus aureus

(2011) Christina E. Lünse et al.   ACS Chemical Biology

Cell-like systems with riboswitch controlled gene expression

(2011) Laura Martini et al.   CHEMICAL COMMUNICATIONS

The Riboswitch Regulates a Thiamine Pyrophosphate ABC Transporter of the Oral Spirochete Treponema denticola

(2011) J. Bian et al.   JOURNAL OF BACTERIOLOGY

Differential Analogue Binding by Two Classes of c-di-GMP Riboswitches

(2011) Carly A. Shanahan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformational capture of the SAM-II riboswitch

(2011) Andrea Haller et al.   Nature Chemical Biology

Challenges of ligand identification for riboswitch candidates

(2011) Michelle M. Meyer et al.   RNA Biology

Mechanism for gene control by a natural allosteric group I ribozyme

(2011) A. G. Y. Chen et al.   RNA

An expanded collection and refined consensus model of glmS ribozymes

(2011) P. J. McCown et al.   RNA

Electropolymerization molecularly imprinted polymer (E-MIP) SPR sensing of drug molecules: Pre-polymerization complexed terthiophene and carbazole electroactive monomers

(2010) Roderick Pernites et al.   BIOSENSORS & BIOELECTRONICS

Microbial biosensors: A review

(2010) Liang Su et al.   BIOSENSORS & BIOELECTRONICS

The RFN riboswitch ofBacillus subtilisis a target for the antibiotic roseoflavin produced byStreptomyces davawensis

(2010) Eva Ott et al.   RNA Biology

Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression

(2010) Elaine R. Lee et al.   RNA Biology

An Allosteric Self-Splicing Ribozyme Triggered by a Bacterial Second Messenger

(2010) E. R. Lee et al.   SCIENCE

Design Strategies for Aptamer-Based Biosensors

(2010) Kun Han et al.   SENSORS

Oncolytic Viruses for Cancer Therapy: Overcoming the Obstacles

(2010) Han Hsi Wong et al.   Viruses-Basel

Riboswitches and the RNA World

(2010) R. R. Breaker   Cold Spring Harbor Perspectives in Biology

Novel Riboswitch Ligand Analogs as Selective Inhibitors of Guanine-Related Metabolic Pathways

(2010) Jérôme Mulhbacher et al.   PLoS Pathogens

Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes

(2010) Zasha Weinberg et al.   GENOME BIOLOGY

Design and Antimicrobial Action of Purine Analogues That Bind Guanine Riboswitches

(2009) Jane N. Kim et al.   ACS Chemical Biology

Amino acid recognition and gene regulation by riboswitches

(2009) Alexander Serganov et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Construction of intragenic synthetic riboswitches for detection of a small molecule

(2009) Joon-Jung Jo et al.   BIOTECHNOLOGY LETTERS

Cocrystal structure of a class I preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase

(2009) Daniel J Klein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Adaptive Ligand Binding by the Purine Riboswitch in the Recognition of Guanine and Adenine Analogs

(2009) Sunny D. Gilbert et al.   STRUCTURE

Structural Basis of Thiamine Pyrophosphate Analogues Binding to the Eukaryotic Riboswitch

(2008) Stéphane Thore et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recombineering mycobacteria and their phages

(2008) Julia C. van Kessel et al.   NATURE REVIEWS MICROBIOLOGY

Structure of the SAM-II riboswitch bound to S-adenosylmethionine

(2008) Sunny D Gilbert et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Riboswitches in Eubacteria Sense the Second Messenger Cyclic Di-GMP

(2008) N. Sudarsan et al.   SCIENCE