Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
出版年份 2020 全文链接
标题
Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
作者
关键词
-
出版物
NATURE CELL BIOLOGY
Volume 22, Issue 8, Pages 973-985
出版商
Springer Science and Business Media LLC
发表日期
2020-08-05
DOI
10.1038/s41556-020-0549-1
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Biological Functions of Autophagy Genes: A Disease Perspective
- (2019) Beth Levine et al. CELL
- Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation
- (2019) Suresh Kumar et al. DEVELOPMENTAL CELL
- Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal
- (2019) Jingyue Jia et al. DEVELOPMENTAL CELL
- The complex relationship between TFEB transcription factor phosphorylation and subcellular localization
- (2018) Rosa Puertollano et al. EMBO JOURNAL
- Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins
- (2018) Suresh Kumar et al. JOURNAL OF CELL BIOLOGY
- Galectins Control mTOR in Response to Endomembrane Damage
- (2018) Jingyue Jia et al. MOLECULAR CELL
- TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy
- (2018) Israel C. Nnah et al. Autophagy
- Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes
- (2017) Monther Abu-Remaileh et al. SCIENCE
- Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
- (2017) Brian M. Castellano et al. SCIENCE
- Phagocytosis Enhances Lysosomal and Bactericidal Properties by Activating the Transcription Factor TFEB
- (2016) Matthew A. Gray et al. CURRENT BIOLOGY
- TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis
- (2016) Santosh Chauhan et al. DEVELOPMENTAL CELL
- Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation
- (2016) Thanh Ngoc Nguyen et al. JOURNAL OF CELL BIOLOGY
- TFEB at a glance
- (2016) Gennaro Napolitano et al. JOURNAL OF CELL SCIENCE
- Development of liquid chromatography-tandem mass spectrometry methods for the quantitation of Anisakis simplex proteins in fish
- (2016) Christiane Kruse Fæste et al. JOURNAL OF CHROMATOGRAPHY A
- MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5
- (2015) Catherine L. Nezich et al. JOURNAL OF CELL BIOLOGY
- IRGM Governs the Core Autophagy Machinery to Conduct Antimicrobial Defense
- (2015) Santosh Chauhan et al. MOLECULAR CELL
- Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation
- (2015) Rui Huang et al. MOLECULAR CELL
- Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
- (2015) Rushika M. Perera et al. NATURE
- Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
- (2015) Diego L. Medina et al. NATURE CELL BIOLOGY
- Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration
- (2015) Grant R. Campbell et al. PLoS Pathogens
- TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
- (2013) Carmine Settembre et al. NATURE CELL BIOLOGY
- The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes
- (2012) Eisuke Itakura et al. CELL
- Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1
- (2012) Liron Bar-Peled et al. CELL
- Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages
- (2012) Paolo S. Manzanillo et al. Cell Host & Microbe
- A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
- (2012) Carmine Settembre et al. EMBO JOURNAL
- The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
- (2012) A. Roczniak-Ferguson et al. Science Signaling
- The Role of Atg Proteins in Autophagosome Formation
- (2011) Noboru Mizushima et al. Annual Review of Cell and Developmental Biology
- AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets
- (2011) Ken Inoki et al. Annual Review of Pharmacology and Toxicology
- Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance
- (2011) Diego L. Medina et al. DEVELOPMENTAL CELL
- Novel Protein Substrates of the Phospho-Form Modification System in Neisseria gonorrhoeae and Their Connection toO-Linked Protein Glycosylation
- (2011) Jan Haug Anonsen et al. INFECTION AND IMMUNITY
- A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease
- (2011) Patrick Brest et al. NATURE GENETICS
- mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase
- (2011) R. Zoncu et al. SCIENCE
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network
- (2011) Isabel Pombo Grégoire et al. PLoS Pathogens
- LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis
- (2010) Hilla Weidberg et al. EMBO JOURNAL
- Network organization of the human autophagy system
- (2010) Christian Behrends et al. NATURE
- Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria
- (2010) Sudha B. Singh et al. NATURE CELL BIOLOGY
- On the level: IRGM gene function is all about expression
- (2009) Alan Huett et al. Autophagy
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Crohn's disease adherent-invasiveEscherichia colicolonize and induce strong gut inflammation in transgenic mice expressing human CEACAM
- (2009) Frédéric A. Carvalho et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Gene Network Regulating Lysosomal Biogenesis and Function
- (2009) Marco Sardiello et al. SCIENCE
- Death and Resurrection of the Human IRGM Gene
- (2009) Cemalettin Bekpen et al. PLoS Genetics
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
- (2008) Steven A McCarroll et al. NATURE GENETICS
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