IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

(2011) Patrick Brest et al.   NATURE GENETICS

Autophagy Protects against Sindbis Virus Infection of the Central Nervous System

(2010) Anthony Orvedahl et al.   Cell Host & Microbe

System-Level Comparison of Protein−Protein Interactions between Viruses and the Human Type I Interferon System Network

(2010) V. Navratil et al.   JOURNAL OF PROTEOME RESEARCH

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria

(2010) Sudha B. Singh et al.   NATURE CELL BIOLOGY

Autophagy, Immunity, and Microbial Adaptations

(2009) Vojo Deretic et al.   Cell Host & Microbe

Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes

(2009) Monique Gannagé et al.   Cell Host & Microbe

Autophagy Induction by the Pathogen Receptor CD46

(2009) Pierre-Emmanuel Joubert et al.   Cell Host & Microbe

Crohn's disease-associated adherent-invasiveE. coliare selectively favoured by impaired autophagy to replicate intracellularly

(2009) Pierre Lapaquette et al.   CELLULAR MICROBIOLOGY

Autophagy Is an Essential Component of Drosophila Immunity against Vesicular Stomatitis Virus

(2009) Spencer Shelly et al.   IMMUNITY

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

(2009) George B. Kyei et al.   JOURNAL OF CELL BIOLOGY

The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway

(2009) Y. T. Zheng et al.   JOURNAL OF IMMUNOLOGY

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P2 and PtdIns(3,4,5)P3 promotes immunity to mycobacteria

(2009) Sangeeta Tiwari et al.   NATURE IMMUNOLOGY

Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells

(2009) Chinnaswamy Jagannath et al.   NATURE MEDICINE

ViralORFeome: an integrated database to generate a versatile collection of viral ORFs

(2009) J. Pellet et al.   NUCLEIC ACIDS RESEARCH

Differential Role of Autophagy in CD4 T Cells and Macrophages during X4 and R5 HIV-1 Infection

(2009) Lucile Espert et al.   PLoS One

The autophagy machinery is required to initiate hepatitis C virus replication

(2009) M. Dreux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy Gene Variant IRGM −261T Contributes to Protection from Tuberculosis Caused by Mycobacterium tuberculosis but Not by M. africanum Strains

(2009) Christopher D. Intemann et al.   PLoS Pathogens

TMEM74, a lysosome and autophagosome protein, regulates autophagy

(2008) Chuanfei Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

(2008) Donna Sir et al.   HEPATOLOGY

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

(2008) Steven A McCarroll et al.   NATURE GENETICS

VirHostNet: a knowledge base for the management and the analysis of proteome-wide virus–host interaction networks

(2008) Vincent Navratil et al.   NUCLEIC ACIDS RESEARCH

Autophagic machinery activated by dengue virus enhances virus replication

(2008) Ying-Ray Lee et al.   VIROLOGY