Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice
出版年份 2020 全文链接
标题
Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice
作者
关键词
-
出版物
Molecular Neurodegeneration
Volume 15, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-06-09
DOI
10.1186/s13024-020-00382-8
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Evidence in support of chromosomal sex influencing plasma based metabolome vs APOE genotype influencing brain metabolome profile in humanized APOE male and female mice
- (2020) Yuan Shang et al. PLoS One
- Extracellular Vesicles Secreted by Astroglial Cells Transport Apolipoprotein D to Neurons and Mediate Neuronal Survival Upon Oxidative Stress
- (2019) Raquel Pascua-Maestro et al. Frontiers in Cellular Neuroscience
- The Role of APOE4 in Disrupting the Homeostatic Functions of Astrocytes and Microglia in Aging and Alzheimer’s Disease
- (2019) Celia G. Fernandez et al. Frontiers in Aging Neuroscience
- ApoE4: an emerging therapeutic target for Alzheimer’s disease
- (2019) Mirna Safieh et al. BMC Medicine
- Apolipoprotein E4, inhibitory network dysfunction, and Alzheimer’s disease
- (2019) Ramsey Najm et al. Molecular Neurodegeneration
- Very Low-Density Lipoproteins of Metabolic Syndrome Modulates STIM1, Suppresses Store-Operated Calcium Entry, and Deranges Myofilament Proteins in Atrial Myocytes
- (2019) Yi-Lin Shiou et al. Journal of Clinical Medicine
- Lysosomes as dynamic regulators of cell and organismal homeostasis
- (2019) Andrea Ballabio et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Apolipoprotein E, Receptors, and Modulation of Alzheimer’s Disease
- (2018) Na Zhao et al. BIOLOGICAL PSYCHIATRY
- The regulation of autophagy by calcium signals: Do we have a consensus?
- (2018) Martin D. Bootman et al. CELL CALCIUM
- Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons
- (2018) Xiu-Tang Cheng et al. JOURNAL OF CELL BIOLOGY
- APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
- (2018) Yuan-Ta Lin et al. NEURON
- Amyloid clearance defect in ApoE4 astrocytes is reversed by epigenetic correction of endosomal pH
- (2018) Hari Prasad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain
- (2018) Matthew M. Boisvert et al. Cell Reports
- In Vivo Two Photon Imaging of Astrocytic Structure and Function in Alzheimer’s Disease
- (2018) Patricia Kelly et al. Frontiers in Aging Neuroscience
- Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau
- (2018) Timothy J. Hohman et al. JAMA Neurology
- Absolute 10-year risk of dementia by age, sex andAPOEgenotype: a population-based cohort study
- (2018) Katrine L. Rasmussen et al. CANADIAN MEDICAL ASSOCIATION JOURNAL
- Apolipoprotein E4 genotype compromises brain exosome production
- (2018) Katherine Y Peng et al. BRAIN
- Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE
- (2018) Samira Parhizkar et al. NATURE NEUROSCIENCE
- Apolipoprotein E in lipoprotein metabolism, health and cardiovascular disease
- (2018) A.David Marais PATHOLOGY
- ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
- (2017) Yang Shi et al. NATURE
- Apolipoprotein E4 causes early olfactory network abnormalities and short-term olfactory memory impairments
- (2017) Katherine Y. Peng et al. NEUROSCIENCE
- Emerging Roles for the Lysosome in Lipid Metabolism
- (2017) Ashley M. Thelen et al. TRENDS IN CELL BIOLOGY
- Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology
- (2017) Tal Nuriel et al. Nature Communications
- ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism
- (2017) Aishwarya Sathyanarayan et al. Cell Reports
- Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress
- (2017) Raquel Pascua-Maestro et al. PLoS Genetics
- Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease
- (2017) Scott C. Neu et al. JAMA Neurology
- The Endosomal–Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo
- (2017) Tal Nuriel et al. Frontiers in Neuroscience
- Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
- (2017) Michiru Nishita et al. Scientific Reports
- CREB decreases astrocytic excitability by modifying subcellular calcium fluxes via the sigma-1 receptor
- (2016) A. Eraso-Pichot et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence
- (2016) Yu Yamazaki et al. CNS DRUGS
- Impaired Autophagy in APOE4 Astrocytes
- (2016) Shira Simonovitch et al. JOURNAL OF ALZHEIMERS DISEASE
- Altered Energy Metabolism Pathways in the Posterior Cingulate in Young Adult Apolipoprotein E ɛ4 Carriers
- (2016) Michelle Perkins et al. JOURNAL OF ALZHEIMERS DISEASE
- Ca2+/H+exchange by acidic organelles regulates cell migration in vivo
- (2016) Manuela Melchionda et al. JOURNAL OF CELL BIOLOGY
- Mechanisms and functions of lysosome positioning
- (2016) Jing Pu et al. JOURNAL OF CELL SCIENCE
- Age, APOE and sex: Triad of risk of Alzheimer’s disease
- (2016) Brandalyn C. Riedel et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
- (2016) Ye Zhang et al. NEURON
- Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes
- (2016) Anna Raffaello et al. TRENDS IN BIOCHEMICAL SCIENCES
- Probing the Complexities of Astrocyte Calcium Signaling
- (2016) Eiji Shigetomi et al. TRENDS IN CELL BIOLOGY
- Apolipoprotein E and Sex Bias in Cerebrovascular Aging of Men and Mice
- (2016) Caleb E. Finch et al. TRENDS IN NEUROSCIENCES
- Intracellular Calcium Dysregulation: Implications for Alzheimer’s Disease
- (2016) Simona Magi et al. Biomed Research International
- A primer of NAADP-mediated Ca2+ signalling: From sea urchin eggs to mammalian cells
- (2015) Antony Galione CELL CALCIUM
- Evolution of acidic Ca2+ stores and their resident Ca2+-permeable channels
- (2015) Sandip Patel et al. CELL CALCIUM
- Diversity of astrocyte functions and phenotypes in neural circuits
- (2015) Baljit S Khakh et al. NATURE NEUROSCIENCE
- Disentangling calcium-driven astrocyte physiology
- (2015) Dmitri A. Rusakov NATURE REVIEWS NEUROSCIENCE
- Autophagy in Alzheimer’s disease
- (2015) Ameneh Zare-shahabadi et al. REVIEWS IN THE NEUROSCIENCES
- Reduced grid-cell-like representations in adults at genetic risk for Alzheimer's disease
- (2015) L. Kunz et al. SCIENCE
- Circuit-specific signaling in astrocyte-neuron networks in basal ganglia pathways
- (2015) R. Martin et al. SCIENCE
- Cholesterol-induced activation of TRPM7 regulates cell proliferation, migration, and viability of human prostate cells
- (2014) Yuyang Sun et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Anti-ApoE Antibody Given after Plaque Onset Decreases A Accumulation and Improves Brain Function in a Mouse Model of A Amyloidosis
- (2014) F. Liao et al. JOURNAL OF NEUROSCIENCE
- Metabolomic study of lipids in serum for biomarker discovery in Alzheimer's disease using direct infusion mass spectrometry
- (2014) R. González-Domínguez et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Altered neurotransmission in the lateral amygdala in aged human apoE4 targeted replacement mice
- (2014) Rebecca C. Klein et al. NEUROBIOLOGY OF AGING
- Gliotransmitters Travel in Time and Space
- (2014) Alfonso Araque et al. NEURON
- A gene−brain−cognition pathway for the effect of an Alzheimer׳s risk gene on working memory in young adults
- (2014) Benson W. Stevens et al. NEUROPSYCHOLOGIA
- Astrocytes contribute to gamma oscillations and recognition memory
- (2014) H. S. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA
- (2014) Junji Suzuki et al. Nature Communications
- Metabotropic P2Y1 receptor signalling mediates astrocytic hyperactivity in vivo in an Alzheimer’s disease mouse model
- (2014) Andrea Delekate et al. Nature Communications
- Astrocytes express functional TRPV2 ion channels
- (2013) Koji Shibasaki et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex
- (2013) G. A. Rodriguez et al. LEARNING & MEMORY
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain
- (2013) E. Hudry et al. Science Translational Medicine
- Astroglial Excitability and Gliotransmission: An Appraisal of Ca2+ as a Signalling Route
- (2012) Robert Zorec et al. ASN Neuro
- Voltage-sensing phosphatase reveals temporal regulation of TRPC3/C6/C7 channels by membrane phosphoinositides
- (2012) Kyohei Itsuki et al. Channels
- Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease
- (2012) Carlos Cruchaga et al. HUMAN MOLECULAR GENETICS
- The endo-lysosomal system as an NAADP-sensitive acidic Ca2+ store: Role for the two-pore channels
- (2011) Sandip Patel et al. CELL CALCIUM
- NAADP mediates ATP-induced Ca2+signals in astrocytes
- (2011) Miquel Barceló-Torns et al. FEBS LETTERS
- Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Regulates Autophagy in Cultured Astrocytes
- (2011) Gustavo J. S. Pereira et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Circadian Regulation of ATP Release in Astrocytes
- (2011) L. Marpegan et al. JOURNAL OF NEUROSCIENCE
- Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca2+ Signaling and Endolysosomal Trafficking
- (2010) Margarida Ruas et al. CURRENT BIOLOGY
- Lipid map of the mammalian cell
- (2010) G. van Meer et al. JOURNAL OF CELL SCIENCE
- Long-term potentiation depends on release of d-serine from astrocytes
- (2010) Christian Henneberger et al. NATURE
- Sex differences in hypothalamic astrocyte response to estradiol stimulation
- (2010) John Kuo et al. Biology of Sex Differences
- Apolipoprotein E4 (1–272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells
- (2009) Toshiyuki Nakamura et al. Molecular Neurodegeneration
- Distinct patterns of brain activity in young carriers of the APOE- 4 allele
- (2009) N. Filippini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Apolipoprotein E ε4 is associated with disease-specific effects on brain atrophy in Alzheimer's disease and frontotemporal dementia
- (2009) Federica Agosta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice
- (2009) K. V. Kuchibhotla et al. SCIENCE
- Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels
- (2008) D. R. Riddell et al. JOURNAL OF NEUROSCIENCE
- Developmental profile and properties of sulforhodamine 101—Labeled glial cells in acute brain slices of rat hippocampus
- (2007) Karl Wolfgang Kafitz et al. JOURNAL OF NEUROSCIENCE METHODS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started