Pharmacological targeting of valosin containing protein (VCP) induces DNA damage and selectively kills canine lymphoma cells

Expression Level of Valosin Containing Protein is Associated with Prognosis of Primary Orbital MALT Lymphoma

(2014) Wen-Wen Zhu et al.   Asian Pacific Journal of Cancer Prevention

Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity

(2014) Marjo-Riitta Puumalainen et al.   Nature Communications

P97/CDC-48: Proteostasis control in tumor cell biology

(2013) Delphine Fessart et al.   CANCER LETTERS

Structure-Activity Relationship Study Reveals ML240 and ML241 as Potent and Selective Inhibitors of p97 ATPase

(2013) Tsui-Fen Chou et al.   ChemMedChem

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

(2013) Paola Magnaghi et al.   Nature Chemical Biology

Combined Inhibition of p97 and the Proteasome Causes Lethal Disruption of the Secretory Apparatus in Multiple Myeloma Cells

(2013) Holger W. Auner et al.   PLoS One

Treatment challenges in the management of relapsed or refractory non-Hodgkin’s lymphoma – novel and emerging therapies

(2013) Mark Chao   Cancer Management and Research

Role of p97/VCP (Cdc48) in genome stability

(2013) Bruno Vaz et al.   Frontiers in Genetics

p97/VCP- and Lys48-linked polyubiquitination form a new signaling pathway in DNA damage response

(2012) Kristijan Ramadan   CELL CYCLE

The dog as a possible animal model for human non-Hodgkin lymphoma: a review

(2012) Laura Marconato et al.   HEMATOLOGICAL ONCOLOGY

Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy

(2011) Yanfen Liu et al.   CELL RESEARCH

Critical Role of VCP/p97 in the Pathogenesis and Progression of Non-Small Cell Lung Carcinoma

(2011) Christopher W. Valle et al.   PLoS One

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

(2011) T.-F. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reading between the lines: molecular characterization of five widely used canine lymphoid tumour cell lines

(2011) E. L. Seiser et al.   Veterinary and Comparative Oncology

2-Anilino-4-aryl-1,3-thiazole inhibitors of valosin-containing protein (VCP or p97)

(2010) Matthew G. Bursavich et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation

(2010) P. Perez-Galan et al.   BLOOD

Imbalances in p97 co-factor interactions in human proteinopathy

(2010) Vanesa Fernández-Sáiz et al.   EMBO REPORTS

Targeted therapy in lymphoma

(2010) Patrick B Johnston et al.   Journal of Hematology & Oncology

Establishment and characterization of a novel canine B-cell line derived from a spontaneously occurring diffuse large cell lymphoma

(2010) Barbara C. Rütgen et al.   LEUKEMIA RESEARCH

Classification of Canine Malignant Lymphomas According to the World Health Organization Criteria

(2010) V. E. Valli et al.   VETERINARY PATHOLOGY

Cancer Incidence in Pet Dogs: Findings of the Animal Tumor Registry of Genoa, Italy

(2009) D.F. Merlo et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

(2009) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionarily conserved cytogenetic changes in hematological malignancies of dogs and humans – man and his best friend share more than companionship

(2008) Matthew Breen et al.   CHROMOSOME RESEARCH

Inhibition of p97-dependent Protein Degradation by Eeyarestatin I

(2008) Qiuyan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY