Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity

DDB2: A Novel Regulator of NF- B and Breast Tumor Invasion

(2013) M. Ennen et al.   CANCER RESEARCH

DDB2 Suppresses Epithelial-to-Mesenchymal Transition in Colon Cancer

(2013) N. Roy et al.   CANCER RESEARCH

Proliferating Cell Nuclear Antigen (PCNA)-binding Protein C1orf124 Is a Regulator of Translesion Synthesis

(2012) Gargi Ghosal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spartan/C1orf124, a Reader of PCNA Ubiquitylation and a Regulator of UV-Induced DNA Damage Response

(2012) Richard C. Centore et al.   MOLECULAR CELL

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

(2012) Hemmo Meyer et al.   NATURE CELL BIOLOGY

DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage

(2012) Emily J Davis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DVC1 (C1orf124) is a DNA damage–targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

(2012) Anna Mosbech et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair

(2012) J. I. Yeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation

(2011) Eric S. Fischer et al.   CELL

DNA damage response and transcription

(2011) Saskia Lagerwerf et al.   DNA REPAIR

Cdc48/p97 Mediates UV-Dependent Turnover of RNA Pol II

(2011) Rati Verma et al.   MOLECULAR CELL

A Genome-wide Screen Identifies p97 as an Essential Regulator of DNA Damage-Dependent CDT1 Destruction

(2011) Malavika Raman et al.   MOLECULAR CELL

CDC-48/p97 Coordinates CDT-1 Degradation with GINS Chromatin Dissociation to Ensure Faithful DNA Replication

(2011) André Franz et al.   MOLECULAR CELL

The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks

(2011) Mayura Meerang et al.   NATURE CELL BIOLOGY

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

(2011) Klara Acs et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of Nucleotide Excision Repair by UV-DDB: Prioritization of Damage Recognition to Internucleosomal DNA

(2011) Jia Fei et al.   PLOS BIOLOGY

DDB2, an Essential Mediator of Premature Senescence

(2010) Nilotpal Roy et al.   MOLECULAR AND CELLULAR BIOLOGY

Coordination of dual incision and repair synthesis in human nucleotide excision repair

(2009) Lidija Staresincic et al.   EMBO JOURNAL

The CUL4 Enigma: Culling DNA Repair Factors

(2009) Kaoru Sugasawa   MOLECULAR CELL

CUL4A Abrogation Augments DNA Damage Response and Protection against Skin Carcinogenesis

(2009) Liren Liu et al.   MOLECULAR CELL

Targeting the ubiquitin system in cancer therapy

(2009) Daniela Hoeller et al.   NATURE

A ubiquitin-selective AAA-ATPase mediates transcriptional switching by remodelling a repressor–promoter DNA complex

(2009) Alexander J. Wilcox et al.   NATURE CELL BIOLOGY

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

DDB2 decides cell fate following DNA damage

(2009) T. Stoyanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cullin 4B-Based UV-Damaged DNA-Binding Protein Ligase Binds to UV-Damaged Chromatin and Ubiquitinates Histone H2A

(2008) J. Guerrero-Santoro et al.   CANCER RESEARCH

Structural Basis of UV DNA-Damage Recognition by the DDB1–DDB2 Complex

(2008) Andrea Scrima et al.   CELL

Impaired Protein Aggregate Handling and Clearance Underlie the Pathogenesis of p97/VCP-associated Disease

(2008) Jeong-Sun Ju et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcription-coupled DNA repair: two decades of progress and surprises

(2008) Philip C. Hanawalt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY