Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain

Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing

(2019) Margarita C. Dinamarca et al.   Nature Communications

Structural integrity in subjective cognitive decline, mild cognitive impairment and Alzheimer’s disease based on multicenter diffusion tensor imaging

(2019) Katharina Brueggen et al.   JOURNAL OF NEUROLOGY

Oligodendrocyte Differentiation and Myelination Is Potentiated via GABAB Receptor Activation

(2019) Mari Paz Serrano-Regal et al.   NEUROSCIENCE

Amyloid Precursor Protein (APP) and GABAergic Neurotransmission

(2019) Bor Luen Tang   Cells

Insoluble Aβ overexpression in an App knock-in mouse model alters microstructure and gamma oscillations in the prefrontal cortex, affecting anxiety-related behaviours

(2019) Eleftheria Pervolaraki et al.   Disease Models & Mechanisms

NURR1 deficiency is associated to ADHD-like phenotypes in mice

(2019) Francesca Montarolo et al.   Translational Psychiatry

Aging, cognition, and the brain: effects of age-related variation in white matter integrity on neuropsychological function

(2018) Yang-Teng Fan et al.   AGING & MENTAL HEALTH

DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer's disease and dementia

(2018) Kai-Hei Tse et al.   Alzheimers & Dementia

Early Nodal and Paranodal Disruption in Autoimmune Optic Neuritis

(2018) Aleksandar Stojic et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

More highly myelinated white matter tracts are associated with faster processing speed in healthy adults

(2018) Sidhant Chopra et al.   NEUROIMAGE

Protective Effects of Sulforaphane on Cognitive Impairments and AD-like Lesions in Diabetic Mice are Associated with the Upregulation of Nrf2 Transcription Activity

(2018) Die Pu et al.   NEUROSCIENCE

The Axon-Myelin Unit in Development and Degenerative Disease

(2018) Ruth M. Stassart et al.   Frontiers in Neuroscience

Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer’s disease mouse model

(2018) Joseph Flores et al.   Nature Communications

Lipocalin 2 contributes to brain iron dysregulation but does not affect cognition, plaque load, and glial activation in the J20 Alzheimer mouse model

(2018) Doortje W. Dekens et al.   Journal of Neuroinflammation

Assessment of spatial learning and memory in the Barnes maze task in rodents—methodological consideration

(2018) Kinga Gawel et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

How Do Cells of the Oligodendrocyte Lineage Affect Neuronal Circuits to Influence Motor Function, Memory and Mood?

(2018) Renee E. Pepper et al.   Frontiers in Cellular Neuroscience

Lineage tracing reveals dynamic changes in oligodendrocyte precursor cells following cuprizone-induced demyelination

(2017) Emily G. Baxi et al.   GLIA

Myelinogenic Plasticity of Oligodendrocyte Precursor Cells following Spinal Cord Contusion Injury

(2017) Peggy Assinck et al.   JOURNAL OF NEUROSCIENCE

Dementia-like pathology in type-2 diabetes: A novel microRNA mechanism

(2017) Anuradha Kalani et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Alterations of myelin morphology and oligodendrocyte development in early stage of Alzheimer’s disease mouse model

(2017) Yu Wu et al.   NEUROSCIENCE LETTERS

Executive Functions in Healthy Older Adults Are Differentially Related to Macro- and Microstructural White Matter Characteristics of the Cerebral Lobes

(2017) Sarah Hirsiger et al.   Frontiers in Aging Neuroscience

Node of Ranvier length as a potential regulator of myelinated axon conduction speed

(2017) I Lorena Arancibia-Cárcamo et al.   eLife

APP modulates KCC2 expression and function in hippocampal GABAergic inhibition

(2017) Ming Chen et al.   eLife

Decreased Glial GABA and Tonic Inhibition in Cerebellum of Mouse Model for Attention-Deficit/Hyperactivity Disorder (ADHD)

(2017) Yoo Sung Kim et al.   Experimental Neurobiology

Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission

(2017) Anna Doshina et al.   Scientific Reports

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

(2016) Seonjoo Lee et al.   ANNALS OF NEUROLOGY

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Endogenous GABA controls oligodendrocyte lineage cell number, myelination, and CNS internode length

(2016) Nicola B. Hamilton et al.   GLIA

ERK1/2 Activation in Preexisting Oligodendrocytes of Adult Mice Drives New Myelin Synthesis and Enhanced CNS Function

(2016) M. A. Jeffries et al.   JOURNAL OF NEUROSCIENCE

Low Density Lipoprotein-Receptor Related Protein 1 Is Differentially Expressed by Neuronal and Glial Populations in the Developing and Mature Mouse Central Nervous System

(2016) Loic Auderset et al.   PLoS One

The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer’s disease

(2015) Sandro Dá Mesquita et al.   BRAIN BEHAVIOR AND IMMUNITY

Oligodendrogenesis in the fornix of adult mouse brain; the effect of LPS-induced inflammatory stimulation

(2015) Shohei Fukushima et al.   BRAIN RESEARCH

The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease

(2015) Jessica M. Collins et al.   EXPERIMENTAL NEUROLOGY

Life Extension Factor Klotho Prevents Mortality and Enhances Cognition in hAPP Transgenic Mice

(2015) D. B. Dubal et al.   JOURNAL OF NEUROSCIENCE

GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury

(2015) Marzieh Zonouzi et al.   NATURE NEUROSCIENCE

Genetic and Stress-Induced Loss of NG2 Glia Triggers Emergence of Depressive-like Behaviors through Reduced Secretion of FGF2

(2015) Fikri Birey et al.   NEURON

Hippocampal Synaptic Expansion Induced by Spatial Experience in Rats Correlates with Improved Information Processing in the Hippocampus

(2015) Mariana Carasatorre et al.   PLoS One

Oligodendrocytes: Myelination and Axonal Support

(2015) Mikael Simons et al.   Cold Spring Harbor Perspectives in Biology

Cerebral Amyloid and Hypertension are Independently Associated with White Matter Lesions in Elderly

(2015) Julia A. Scott et al.   Frontiers in Aging Neuroscience

Chronic Microdose Lithium Treatment Prevented Memory Loss and Neurohistopathological Changes in a Transgenic Mouse Model of Alzheimer's Disease

(2015) Marielza Andrade Nunes et al.   PLoS One

Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue

(2014) Nicolas Snaidero et al.   CELL

White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults

(2014) Brian T. Gold et al.   NEUROBIOLOGY OF AGING

Multiple Modes of Communication between Neurons and Oligodendrocyte Precursor Cells

(2014) Paloma P. Maldonado et al.   NEUROSCIENTIST

Amyloid precursor protein at node of Ranvier modulates nodal formation

(2014) De-En Xu et al.   Cell Adhesion & Migration

Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: A multimodal imaging investigation

(2014) Annie M. Racine et al.   NeuroImage-Clinical

Differential, dominant activation and inhibition of Notch signalling and APP cleavage by truncations of PSEN1 in human disease

(2013) Morgan Newman et al.   HUMAN MOLECULAR GENETICS

NG2 Cells in White Matter But Not Gray Matter Proliferate in Response to PDGF

(2013) R. A. Hill et al.   JOURNAL OF NEUROSCIENCE

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

(2013) Kaylene M. Young et al.   NEURON

White matter plasticity in adulthood

(2013) S. Wang et al.   NEUROSCIENCE

Neuroinflammation and Neuronal Loss Precede Aβ Plaque Deposition in the hAPP-J20 Mouse Model of Alzheimer’s Disease

(2013) Amanda L. Wright et al.   PLoS One

A Shortened Barnes Maze Protocol Reveals Memory Deficits at 4-Months of Age in the Triple-Transgenic Mouse Model of Alzheimer's Disease

(2013) Aida Attar et al.   PLoS One

Cuprizone-induced demyelination in mice: age-related vulnerability and exploratory behavior deficit

(2013) Hongkai Wang et al.   Neuroscience Bulletin

White matter tract integrity metrics reflect the vulnerability of late-myelinating tracts in Alzheimer's disease

(2013) Andreana Benitez et al.   NeuroImage-Clinical

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

(2012) Laure Verret et al.   CELL

Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men

(2012) Gwendolyn Behrendt et al.   GLIA

Bicarbonate efflux via GABAA receptors depolarizes membrane potential and inhibits two-pore domain potassium channels of astrocytes in rat hippocampal slices

(2012) Bao-Feng Ma et al.   GLIA

Properties and Fate of Oligodendrocyte Progenitor Cells in the Corpus Callosum, Motor Cortex, and Piriform Cortex of the Mouse

(2012) L. E. Clarke et al.   JOURNAL OF NEUROSCIENCE

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model

(2012) P. E. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin receptor mutation results in insulin resistance and hyperinsulinemia but does not exacerbate Alzheimer’s-like phenotypes in mice

(2011) Kazuma Murakami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Extensive aspartoacylase expression in the rat central nervous system

(2011) John R. Moffett et al.   GLIA

An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction

(2011) Maya K. Desai et al.   GLIA

Ablation of Cellular Prion Protein Does Not Ameliorate Abnormal Neural Network Activity or Cognitive Dysfunction in the J20 Line of Human Amyloid Precursor Protein Transgenic Mice

(2011) M. Cisse et al.   JOURNAL OF NEUROSCIENCE

Multiple Indices of Diffusion Identifies White Matter Damage in Mild Cognitive Impairment and Alzheimer’s Disease

(2011) Laurence O'Dwyer et al.   PLoS One

Focal demyelination in Alzheimer’s disease and transgenic mouse models

(2010) Stanislaw Mitew et al.   ACTA NEUROPATHOLOGICA

In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks

(2010) Steffen Burgold et al.   ACTA NEUROPATHOLOGICA

Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target

(2010) Maya K. Desai et al.   AMERICAN JOURNAL OF PATHOLOGY

CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

(2010) Malgorzata Zawadzka et al.   Cell Stem Cell

NG2 Glia Generate New Oligodendrocytes But Few Astrocytes in a Murine Experimental Autoimmune Encephalomyelitis Model of Demyelinating Disease

(2010) R. B. Tripathi et al.   JOURNAL OF NEUROSCIENCE

Many Neuronal and Behavioral Impairments in Transgenic Mouse Models of Alzheimer's Disease Are Independent of Caspase Cleavage of the Amyloid Precursor Protein

(2010) J. A. Harris et al.   JOURNAL OF NEUROSCIENCE

Amyloid β1–42 oligomer inhibits myelin sheet formation in vitro

(2010) Makoto Horiuchi et al.   NEUROBIOLOGY OF AGING

NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration

(2010) Shin H. Kang et al.   NEURON

White matter damage in frontotemporal dementia and Alzheimer's disease measured by diffusion MRI

(2009) Y. Zhang et al.   BRAIN

Neprilysin Overexpression Inhibits Plaque Formation But Fails to Reduce Pathogenic A  Oligomers and Associated Cognitive Deficits in Human Amyloid Precursor Protein Transgenic Mice

(2009) W. J. Meilandt et al.   JOURNAL OF NEUROSCIENCE

What does the retrosplenial cortex do?

(2009) Seralynne D. Vann et al.   NATURE REVIEWS NEUROSCIENCE

Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination

(2009) Yueting Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

(2008) Maya K. Desai et al.   GLIA

Progeny of Olig2-Expressing Progenitors in the Gray and White Matter of the Adult Mouse Cerebral Cortex

(2008) L. Dimou et al.   JOURNAL OF NEUROSCIENCE

PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

(2008) Leanne E Rivers et al.   NATURE NEUROSCIENCE

Clinical severity of Alzheimer's disease is associated with PIB uptake in PET

(2008) Timo Grimmer et al.   NEUROBIOLOGY OF AGING

Decreased white matter integrity in late-myelinating fiber pathways in Alzheimer's disease supports retrogenesis

(2008) N.H. Stricker et al.   NEUROIMAGE