标题
Multiple roles of caspase‐8 in cell death, inflammation, and innate immunity
作者
关键词
-
出版物
JOURNAL OF LEUKOCYTE BIOLOGY
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2020-06-13
DOI
10.1002/jlb.3mr0420-305r
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation
- (2020) Hayley I. Muendlein et al. SCIENCE
- RIPK1 can mediate apoptosis in addition to necroptosis during embryonic development
- (2019) Xuhua Zhang et al. Cell Death & Disease
- Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP3 inflammasome assembly
- (2019) Kaiwen W Chen et al. EMBO JOURNAL
- The molecular machinery of regulated cell death
- (2019) Daolin Tang et al. CELL RESEARCH
- Targeting RIPK1 for the treatment of human diseases
- (2019) Alexei Degterev et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
- (2019) Corey Rogers et al. Nature Communications
- Caspase-8 restricts antiviral CD8 T cell hyperaccumulation
- (2019) Yanjun Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation
- (2019) Sabrina Sofia Burgener et al. Cell Reports
- TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages
- (2019) Harald Wajant et al. Frontiers in Cell and Developmental Biology
- Pannexin‐1 promotes NLRP3 activation during apoptosis but is dispensable for canonical or noncanonical inflammasome activation
- (2019) Kaiwen W. Chen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis
- (2019) Kim Newton et al. NATURE
- Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis
- (2019) Melanie Fritsch et al. NATURE
- Activity of caspase-8 determines plasticity between cell death pathways
- (2019) Kim Newton et al. NATURE
- Pharmacological Inhibitors of the NLRP3 Inflammasome
- (2019) Ayesha Zahid et al. Frontiers in Immunology
- Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease
- (2019) Najoua Lalaoui et al. NATURE
- A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1
- (2019) Panfeng Tao et al. NATURE
- Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming
- (2018) Anette Christ et al. CELL
- Caspase selective reagents for diagnosing apoptotic mechanisms
- (2018) Marcin Poreba et al. CELL DEATH AND DIFFERENTIATION
- Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3
- (2018) Tae-Bong Kang et al. CELL DEATH AND DIFFERENTIATION
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis
- (2018) Rui Kang et al. Cell Host & Microbe
- Mechanism of membrane pore formation by human gasdermin‐D
- (2018) Estefania Mulvihill et al. EMBO JOURNAL
- The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
- (2018) Charles L. Evavold et al. IMMUNITY
- Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1
- (2018) Monica L. Gonzalez Ramirez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation
- (2018) R.K. Subbarao Malireddi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity
- (2018) Dave Boucher et al. JOURNAL OF EXPERIMENTAL MEDICINE
- BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
- (2018) Kate McArthur et al. SCIENCE
- Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death
- (2018) Hiroto Kambara et al. Cell Reports
- Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis
- (2018) Joel S Riley et al. EMBO JOURNAL
- In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus
- (2018) Raimunda S. S. Azevedo et al. Scientific Reports
- Intestinal Inflammation and Dysregulated Immunity in Patients With Inherited Caspase-8 Deficiency
- (2018) Anna S. Lehle et al. GASTROENTEROLOGY
- RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation
- (2018) Gianmaria Liccardi et al. MOLECULAR CELL
- PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation
- (2018) Jueqi Chen et al. NATURE
- Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
- (2018) Joseph Sarhan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death
- (2018) Pontus Orning et al. SCIENCE
- ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation
- (2018) Sebastian Rühl et al. SCIENCE
- The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation
- (2018) James E. Vince et al. Cell Reports
- BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages
- (2018) Dhruv Chauhan et al. Cell Reports
- NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8
- (2017) Isabella Rauch et al. IMMUNITY
- NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain
- (2017) Andrea Stutz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D
- (2017) Kimberley D. Gutierrez et al. JOURNAL OF IMMUNOLOGY
- The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2
- (2017) Torsten Hartwig et al. MOLECULAR CELL
- DNA Damage in Stem Cells
- (2017) Ilio Vitale et al. MOLECULAR CELL
- Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation
- (2017) Conor M. Henry et al. MOLECULAR CELL
- Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
- (2017) Yupeng Wang et al. NATURE
- Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
- (2017) Corey Rogers et al. Nature Communications
- Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4
- (2017) Nina Van Opdenbosch et al. Cell Reports
- Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival
- (2017) Sebastian Horn et al. Cell Reports
- The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity
- (2017) Katharina S. Schneider et al. Cell Reports
- Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome
- (2017) Danielle P. A. Mascarenhas et al. PLoS Pathogens
- Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells
- (2017) Pedro Lee et al. eLife
- MLKL forms cation channels
- (2016) Bingqing Xia et al. CELL RESEARCH
- GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
- (2016) Lorenzo Sborgi et al. EMBO JOURNAL
- The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis
- (2016) Silvia Alvarez-Diaz et al. IMMUNITY
- The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
- (2016) Mervyn Singer et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis
- (2016) Ine Jorgensen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Reassessing the Evolutionary Importance of Inflammasomes
- (2016) Vivien I. Maltez et al. JOURNAL OF IMMUNOLOGY
- Pore-forming activity and structural autoinhibition of the gasdermin family
- (2016) Jingjin Ding et al. NATURE
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
- (2016) Yuan He et al. NATURE
- GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
- (2016) Robin A. Aglietti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Balance between short and long isoforms of cFLIP regulates Fas-mediated apoptosis in vivo
- (2016) Daniel R. Ram et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia
- (2016) Gabriela Brumatti et al. Science Translational Medicine
- MLKL and FADD Are Critical for Suppressing Progressive Lymphoproliferative Disease and Activating the NLRP3 Inflammasome
- (2016) Xixi Zhang et al. Cell Reports
- Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death
- (2016) Naomi H. Philip et al. PLoS Pathogens
- Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis
- (2016) Mary Speir et al. Nature Microbiology
- Microbial Degradation of Cellular Kinases Impairs Innate Immune Signaling and Paracrine TNFα Responses
- (2016) Kenneth Barth et al. Scientific Reports
- Novel Roles for Caspase-8 in IL-1β and Inflammasome Regulation
- (2015) Prajwal Gurung et al. AMERICAN JOURNAL OF PATHOLOGY
- Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome
- (2015) Yiqing Yan et al. CELL
- Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium
- (2015) Youssef Aachoui et al. Cell Host & Microbe
- Caspase-11 activates a canonical NLRP3 inflammasome by promoting K+efflux
- (2015) Sebastian Rühl et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments
- (2015) Parimala R. Vajjhala et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation
- (2015) Jonathan L. Schmid-Burgk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Caspase-8 Deficiency Presenting as Late-Onset Multi-Organ Lymphocytic Infiltration with Granulomas in two Adult Siblings
- (2015) Julie Niemela et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component
- (2015) Hexin Shi et al. NATURE IMMUNOLOGY
- Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis
- (2015) Gregor Ebert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Necroptosis: The Trojan horse in cell autonomous antiviral host defense
- (2015) Edward S. Mocarski et al. VIROLOGY
- RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
- (2015) Kate E. Lawlor et al. Nature Communications
- Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production
- (2014) Michael J. White et al. CELL
- RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis
- (2014) James A. Rickard et al. CELL
- RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3
- (2014) Christopher P. Dillon et al. CELL
- Epithelium-Intrinsic NAIP/NLRC4 Inflammasome Drives Infected Enterocyte Expulsion to Restrict Salmonella Replication in the Intestinal Mucosa
- (2014) Mikael E. Sellin et al. Cell Host & Microbe
- Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens
- (2014) Leigh A. Knodler et al. Cell Host & Microbe
- Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming
- (2014) R. Allam et al. EMBO REPORTS
- Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways
- (2014) Claudia Günther et al. GUT
- Mutation of a Self-Processing Site in Caspase-8 Compromises Its Apoptotic but Not Its Nonapoptotic Functions in Bacterial Artificial Chromosome-Transgenic Mice
- (2014) T.-B. Kang et al. JOURNAL OF IMMUNOLOGY
- Neutrophil Chemokines KC and Macrophage-Inflammatory Protein-2 Are Newly Synthesized by Tissue Macrophages Using Distinct TLR Signaling Pathways
- (2014) K. De Filippo et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo
- (2014) Apostolos Polykratis et al. JOURNAL OF IMMUNOLOGY
- Caspase-8 Modulates Dectin-1 and Complement Receptor 3–Driven IL-1β Production in Response to β-Glucans and the Fungal Pathogen,Candida albicans
- (2014) Sandhya Ganesan et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice
- (2014) S. B. Berger et al. JOURNAL OF IMMUNOLOGY
- FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes
- (2014) P. Gurung et al. JOURNAL OF IMMUNOLOGY
- Enterovirus 71 3C Inhibits Cytokine Expression through Cleavage of the TAK1/TAB1/TAB2/TAB3 Complex
- (2014) X. Lei et al. JOURNAL OF VIROLOGY
- Inflammatory caspases are innate immune receptors for intracellular LPS
- (2014) Jianjin Shi et al. NATURE
- The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
- (2014) Bernardo S Franklin et al. NATURE IMMUNOLOGY
- Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF- B and MAPK signaling
- (2014) N. H. Philip et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death
- (2014) D. Weng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition
- (2014) W. J. Kaiser et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The immunological function of familial Mediterranean fever disease protein Pyrin
- (2014) JieLing Yang et al. Science China-Life Sciences
- Many players in BCL-2 family affairs
- (2014) Tudor Moldoveanu et al. TRENDS IN BIOCHEMICAL SCIENCES
- Caspase crosstalk: integration of apoptotic and innate immune signalling pathways
- (2014) Emma M. Creagh TRENDS IN IMMUNOLOGY
- MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates
- (2014) Yves Dondelinger et al. Cell Reports
- XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation
- (2014) Monica Yabal et al. Cell Reports
- TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice
- (2014) James A Rickard et al. eLife
- Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
- (2014) Snehlata Kumari et al. eLife
- Ambiguities in NLRP3 inflammasome regulation: Is there a role for mitochondria?
- (2013) Kate E. Lawlor et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC
- (2013) V Sagulenko et al. CELL DEATH AND DIFFERENTIATION
- Inflammasomes and host defenses against bacterial infections
- (2013) Gregory I Vladimer et al. CURRENT OPINION IN MICROBIOLOGY
- K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
- (2013) Raúl Muñoz-Planillo et al. IMMUNITY
- Caspase Inhibitors Protect Neurons by Enabling Selective Necroptosis of Inflamed Microglia
- (2013) Michael Fricker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Salmonella Infection Induces Recruitment of Caspase-8 to the Inflammasome To Modulate IL-1 Production
- (2013) S. M. Man et al. JOURNAL OF IMMUNOLOGY
- Proapoptotic Chemotherapeutic Drugs Induce Noncanonical Processing and Release of IL-1 via Caspase-8 in Dendritic Cells
- (2013) C. Antonopoulos et al. JOURNAL OF IMMUNOLOGY
- Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
- (2013) Peter E. Czabotar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock
- (2013) J. A. Hagar et al. SCIENCE
- Caspase-11 Protects Against Bacteria That Escape the Vacuole
- (2013) Y. Aachoui et al. SCIENCE
- Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
- (2013) N. Kayagaki et al. SCIENCE
- Mechanisms of Action of Bcl-2 Family Proteins
- (2013) A. Shamas-Din et al. Cold Spring Harbor Perspectives in Biology
- Caspase Substrates and Inhibitors
- (2013) M. Poreba et al. Cold Spring Harbor Perspectives in Biology
- A Vibrio parahaemolyticus T3SS Effector Mediates Pathogenesis by Independently Enabling Intestinal Colonization and Inhibiting TAK1 Activation
- (2013) Xiaohui Zhou et al. Cell Reports
- cFLIP Regulates Skin Homeostasis and Protects against TNF-Induced Keratinocyte Apoptosis
- (2013) Diana Panayotova-Dimitrova et al. Cell Reports
- Subversion of inflammasome activation and pyroptosis by pathogenic bacteria
- (2013) Larissa D. Cunha et al. Frontiers in Cellular and Infection Microbiology
- The CARD plays a critical role in ASC foci formation and inflammasome signalling
- (2012) Martina Proell et al. BIOCHEMICAL JOURNAL
- Caspase-8 is essential for maintaining chromosomal stability and suppressing B-cell lymphomagenesis
- (2012) A. Hakem et al. BLOOD
- The inflammasome and danger associated molecular patterns (DAMPs) are implicated in cytokine and chemokine responses following stressor exposure
- (2012) Thomas Maslanik et al. BRAIN BEHAVIOR AND IMMUNITY
- TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cancers
- (2012) Anurag Singh et al. CELL
- TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria
- (2012) Vijay A.K. Rathinam et al. CELL
- Caspase-11 Promotes the Fusion of Phagosomes Harboring Pathogenic Bacteria with Lysosomes by Modulating Actin Polymerization
- (2012) Anwari Akhter et al. IMMUNITY
- Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation
- (2012) James E. Vince et al. IMMUNITY
- Caspase-8 Blocks Kinase RIPK3-Mediated Activation of the NLRP3 Inflammasome
- (2012) Tae-Bong Kang et al. IMMUNITY
- Pannexin 1, an ATP Release Channel, Is Activated by Caspase Cleavage of Its Pore-associated C-terminal Autoinhibitory Region
- (2012) Joanna K. Sandilos et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The IL-1-Dependent Sterile Inflammatory Response Has a Substantial Caspase-1-Independent Component That Requires Cathepsin C
- (2012) H. Kono et al. JOURNAL OF IMMUNOLOGY
- Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome
- (2012) Sonja I Gringhuis et al. NATURE IMMUNOLOGY
- Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
- (2012) Charles A. Dinarello et al. NATURE REVIEWS DRUG DISCOVERY
- SAP and XIAP deficiency in hemophagocytic lymphohistiocytosis
- (2012) Xi Yang et al. PEDIATRICS INTERNATIONAL
- PROSPER: An Integrated Feature-Based Tool for Predicting Protease Substrate Cleavage Sites
- (2012) Jiangning Song et al. PLoS One
- NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis
- (2012) M. Inoue et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Serine/threonine acetylation of TGF -activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling
- (2012) N. Paquette et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Survival Function of the FADD-CASPASE-8-cFLIPL Complex
- (2012) Christopher P. Dillon et al. Cell Reports
- The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
- (2011) Beckley K. Davis et al. Annual Review of Immunology
- The NLRP3 inflammasome in health and disease: the good, the bad and the ugly
- (2011) P. Menu et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Loss of Caspase-8 Protects Mice Against Inflammation-Related Hepatocarcinogenesis but Induces Non-Apoptotic Liver Injury
- (2011) Christian Liedtke et al. GASTROENTEROLOGY
- RIG-I RNA Helicase Activation of IRF3 Transcription Factor Is Negatively Regulated by Caspase-8-Mediated Cleavage of the RIP1 Protein
- (2011) Akhil Rajput et al. IMMUNITY
- Cellular FLICE-inhibitory Protein (cFLIP) Isoforms Block CD95- and TRAIL Death Receptor-induced Gene Induction Irrespective of Processing of Caspase-8 or cFLIP in the Death-inducing Signaling Complex
- (2011) Shyam M. Kavuri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cell death and infection: A double-edged sword for host and pathogen survival
- (2011) Hiroshi Ashida et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
- (2011) Ariel C. Bulua et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NLRP3/Caspase-1-Independent IL-1 Production Mediates Diesel Exhaust Particle-Induced Pulmonary Inflammation
- (2011) S. Provoost et al. JOURNAL OF IMMUNOLOGY
- Pannexin-1 Is Required for ATP Release during Apoptosis but Not for Inflammasome Activation
- (2011) Y. Qu et al. JOURNAL OF IMMUNOLOGY
- The IRF-3/Bax-Mediated Apoptotic Pathway, Activated by Viral Cytoplasmic RNA and DNA, Inhibits Virus Replication
- (2011) S. Chattopadhyay et al. JOURNAL OF VIROLOGY
- cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
- (2011) Maria Feoktistova et al. MOLECULAR CELL
- The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
- (2011) Tencho Tenev et al. MOLECULAR CELL
- Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis
- (2011) Claudia Günther et al. NATURE
- RIP3 mediates the embryonic lethality of caspase-8-deficient mice
- (2011) William J. Kaiser et al. NATURE
- Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis
- (2011) Andrew Oberst et al. NATURE
- Functional complementation between FADD and RIP1 in embryos and lymphocytes
- (2011) Haibing Zhang et al. NATURE
- Non-canonical inflammasome activation targets caspase-11
- (2011) Nobuhiko Kayagaki et al. NATURE
- Genetics of monogenic autoinflammatory diseases: past successes, future challenges
- (2011) Ivona Aksentijevich et al. Nature Reviews Rheumatology
- Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
- (2011) S. He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of the leucine-rich repeat (LRR) domain of cryopyrin/NALP3 in monosodium urate crystal-induced inflammation
- (2010) Hal M. Hoffman et al. ARTHRITIS AND RHEUMATISM
- Caspase-8 as a therapeutic target in cancer
- (2010) Dwayne G. Stupack CANCER LETTERS
- Inflammasome Inhibition as a Pathogenic Stealth Mechanism
- (2010) Debra J. Taxman et al. Cell Host & Microbe
- Manipulation of Host Cell Death Pathways during Microbial Infections
- (2010) Mohamed Lamkanfi et al. Cell Host & Microbe
- Crossing paths: interactions between the cell death machinery and growth factor survival signals
- (2010) Gabriela Brumatti et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cutting Edge: Caspase-1 Independent IL-1 Production Is Critical for Host Resistance to Mycobacterium tuberculosis and Does Not Require TLR Signaling In Vivo
- (2010) K. D. Mayer-Barber et al. JOURNAL OF IMMUNOLOGY
- NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses
- (2010) D. Gris et al. JOURNAL OF IMMUNOLOGY
- The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18
- (2010) S. Jha et al. JOURNAL OF NEUROSCIENCE
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
- (2010) Faraaz B. Chekeni et al. NATURE
- Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
- (2010) Edward A Miao et al. NATURE IMMUNOLOGY
- Mitochondria and cell death: outer membrane permeabilization and beyond
- (2010) Stephen W. G. Tait et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8
- (2010) C. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome
- (2010) A. Simon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Inflammasomes: Guardians of the Body
- (2009) Fabio Martinon et al. Annual Review of Immunology
- Caspase 1âindependent activation of interleukin-1β in neutrophil-predominant inflammation
- (2009) Monica Guma et al. ARTHRITIS AND RHEUMATISM
- Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
- (2009) Sudan He et al. CELL
- Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases
- (2009) Alexander U. Lüthi et al. IMMUNITY
- Asc and Ipaf Inflammasomes Direct Distinct Pathways for Caspase-1 Activation in Response to Legionella pneumophila
- (2009) C. L. Case et al. INFECTION AND IMMUNITY
- Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
- (2009) Andrew Kovalenko et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-1β Augments TNF-α–Mediated Inflammatory Responses from Lung Epithelial Cells
- (2009) Sara Saperstein et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- The Effects of Interleukin-1βin Tumor Necrosis Factor-α-Induced Acute Pulmonary Inflammation in Mice
- (2009) Sara Saperstein et al. MEDIATORS OF INFLAMMATION
- Reconstitution of the Death-Inducing Signaling Complex Reveals a Substrate Switch that Determines CD95-Mediated Death or Survival
- (2009) Michelle A. Hughes et al. MOLECULAR CELL
- Death receptor signal transducers: nodes of coordination in immune signaling networks
- (2009) Nicholas S Wilson et al. NATURE IMMUNOLOGY
- Pyroptosis: host cell death and inflammation
- (2009) Tessa Bergsbaken et al. NATURE REVIEWS MICROBIOLOGY
- Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
- (2009) Fiona A. Sharp et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutational analyses of c-FLIPR, the only murine short FLIP isoform, reveal requirements for DISC recruitment
- (2008) N Ueffing et al. CELL DEATH AND DIFFERENTIATION
- Genetic Defects of Apoptosis and Primary Immunodeficiency
- (2008) Helen C. Su et al. IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
- Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8
- (2008) Jonathan Maelfait et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The NALP3 inflammasome is involved in the innate immune response to amyloid-β
- (2008) Annett Halle et al. NATURE IMMUNOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now