C-Type Lectins in Veterinary Species: Recent Advancements and Applications

Active fractions of mannoproteins derived from yeast cell wall stimulate innate and acquired immunity of adult and elderly dogs

(2020) F.S.A. Kroll et al.   ANIMAL FEED SCIENCE AND TECHNOLOGY

Lectin microarrays for glycoproteomics: an overview of their use and potential

(2020) Hanjie Yu et al.   Expert Review of Proteomics

Mammalian lectin arrays for screening host-microbe interactions

(2020) Sabine A. F. Jégouzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-nucleotide polymorphisms in CLEC7A, CD209 and TLR4 gene and their association with susceptibility to paratuberculosis in Indian cattle

(2020) B. Gopi et al.   JOURNAL OF GENETICS

Innate Immune Responses of Skin Mucosa in Common Carp (Cyprinus Carpio) Fed a Diet Supplemented with Galactooligosaccharides

(2020) Elzbieta Pietrzak et al.   Animals

Injection Vaccines Formulated with Nucleotide, Liposomal or Mineral Oil Adjuvants Induce Distinct Differences in Immunogenicity in Rainbow Trout

(2020) Kasper Rømer Villumsen et al.   Vaccines

MOLECULAR INVESTIGATION OF VECTOR-BORNE PATHOGENS IN RED FOXES (VULPES VULPES) FROM SOUTHERN FRANCE

(2020) Hacène Medkour et al.   JOURNAL OF WILDLIFE DISEASES

Molecular identification of Toxoplasma gondii in domesticated and broiler chickens (Gallus domesticus) that possibly augment the pool of human toxoplasmosis

(2020) Muhammad Bar Khan et al.   PLoS One

Investigating the epithelial barrier and immune signatures in the pathogenesis of equine insect bite hypersensitivity

(2020) Iva Cvitas et al.   PLoS One

Characterization and Functional Analysis of Two Transmembrane C-Type Lectins in Obscure Puffer (Takifugu obscurus)

(2020) Ying Huang et al.   Frontiers in Immunology

CD209 C-Type Lectins Promote Host Invasion, Dissemination, and Infection of Toxoplasma gondii

(2020) Olivia Adhiambo Njiri et al.   Frontiers in Immunology

Characterization of the Porcine CLEC12A and Analysis of Its Expression on Blood Dendritic Cell Subsets

(2020) Belén Álvarez et al.   Frontiers in Immunology

Pustulan Activates Chicken Bone Marrow-Derived Dendritic Cells In Vitro and Promotes Ex Vivo CD4+ T Cell Recall Response to Infectious Bronchitis Virus

(2020) Frederik T. Larsen et al.   Vaccines

The functional relevance of shrimp C-type lectins in host-pathogen interactions

(2020) Xian-Wei Wang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Dietary Bacillus amyloliquefaciens enhance survival of white spot syndrome virus infected crayfish

(2020) Yongyong Lai et al.   FISH & SHELLFISH IMMUNOLOGY

Ovine C-type lectin receptor hFc-fusion protein library – A novel platform to screen for host-pathogen interactions

(2020) Dimitri L. Lindenwald et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Porcine CLEC12B is expressed on alveolar macrophages and blood dendritic cells

(2020) Elvira Nieto-Pelegrín et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Association of Bovine CLEC7A gene polymorphism with host susceptibility to paratuberculosis disease in Indian cattle

(2019) Satish Kumar et al.   RESEARCH IN VETERINARY SCIENCE

Impact of uterine macrophage phenotype on placental retention in dairy cows

(2019) Rahul K. Nelli et al.   THERIOGENOLOGY

Expression and function of macrophage-inducible C-type lectin (Mincle) in inflammation driven parturition in fetal membranes and myometrium

(2019) R. Lim et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

NGPhylogeny.fr: new generation phylogenetic services for non-specialists

(2019) Frédéric Lemoine et al.   NUCLEIC ACIDS RESEARCH

“Stuck on sugars – how carbohydrates regulate cell adhesion, recognition, and signaling”

(2019) Richard D. Cummings   GLYCOCONJUGATE JOURNAL

Molecular Detection of Leishmania spp. in Skin and Blood of Stray Dogs from Endemic Areas of Cutaneous Leishmaniasis in Saudi Arabia

(2019) Abdullah D. ALANAZI et al.   Iranian Journal of Parasitology

Construction and expression of a single-chain variable fragment antibody against chicken DEC 205 for targeting the bacterial expressed hemagglutinin-neuraminidase of Newcastle disease virus

(2019) David Jáuregui-Zúñiga et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

The C-type Lectin Receptor CLEC12A Recognizes Plasmodial Hemozoin and Contributes to Cerebral Malaria Development

(2019) Marie-Kristin Raulf et al.   Cell Reports

Microbiota Inhibit Epithelial Pathogen Adherence by Epigenetically Regulating C-Type Lectin Expression

(2019) Vivienne Woo et al.   Frontiers in Immunology

C-type lectin receptor-mediated immune recognition and response of the microbiota in the gut

(2019) Tian-Hang Li et al.   Gastroenterology Report

Assessment of Vaccine-Induced Immunity Against Canine Visceral Leishmaniasis

(2019) Javier Moreno   Frontiers in Veterinary Science

The uric acid crystal receptor Clec12A potentiates type I interferon responses

(2019) Kai Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial glycans and their interactions with lectins in the innate immune system

(2019) Mariano Prado Acosta et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

CD23 is a glycan-binding receptor in some mammalian species

(2019) Sabine A. F. Jégouzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and tissue-expression profiling of novel chicken c-type lectin-like domain containing proteins as potential targets for carbohydrate-based vaccine strategies

(2019) Frederik T. Larsen et al.   MOLECULAR IMMUNOLOGY

Nutraceuticals

(2019) Michael A. Ballou et al.   VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE

Analysis of Swine Conventional Dendritic Cells, DEC205+CD172a+/−CADM1+, from Blood and Spleen in Response to PRRSV and PEDV

(2019) Héctor Parra-Sánchez et al.   Viruses-Basel

The genetic architecture of helminth-specific immune responses in a wild population of Soay sheep (Ovis aries)

(2019) Alexandra M. Sparks et al.   PLoS Genetics

Mincle and STING-Stimulating Adjuvants Elicit Robust Cellular Immunity and Drive Long-Lasting Memory Responses in a Foot-and-Mouth Disease Vaccine

(2019) Min Ja Lee et al.   Frontiers in Immunology

The signaling relations between three adaptors of porcine C-type lectin receptor pathway

(2019) Sen Jiang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Phylogenetic insights on Leishmania detected in cats as revealed by nucleotide sequence analysis of multiple genetic markers

(2019) André Pereira et al.   INFECTION GENETICS AND EVOLUTION

Aryl Trehalose Derivatives as Vaccine Adjuvants for Mycobacterium tuberculosis

(2019) Kendal T. Ryter et al.   JOURNAL OF MEDICINAL CHEMISTRY

T Cell Antifungal Immunity and the Role of C-Type Lectin Receptors

(2019) Emily A. Speakman et al.   TRENDS IN IMMUNOLOGY

Early antibody response and clinical outcome in experimental canine leishmaniasis

(2019) Ana Isabel Olías-Molero et al.   Scientific Reports

Insect C-type lectins in innate immunity

(2018) Xiaofeng Xia et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Glycointeractions in bacterial pathogenesis

(2018) Jessica Poole et al.   NATURE REVIEWS MICROBIOLOGY

Behavioral Nutraceuticals and Diets

(2018) Jillian M. Orlando   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

Single nucleotide variants in innate immune genes associated with Salmonella shedding and colonization in swine on commercial farms

(2018) Margaret H. Ainslie-Garcia et al.   VETERINARY MICROBIOLOGY

C-Type Lectin Receptor (CLR)–Fc Fusion Proteins As Tools to Screen for Novel CLR/Bacteria Interactions: An Exemplary Study on Preselected Campylobacter jejuni Isolates

(2018) Sabine Mayer et al.   Frontiers in Immunology

Flexible Signaling of Myeloid C-Type Lectin Receptors in Immunity and Inflammation

(2018) Carlos del Fresno et al.   Frontiers in Immunology

C-Type Lectin-Like Receptors As Emerging Orchestrators of Sterile Inflammation Represent Potential Therapeutic Targets

(2018) Elise Chiffoleau   Frontiers in Immunology

The Syk-Coupled C-Type Lectin Receptors Dectin-2 and Dectin-3 Are Involved in Paracoccidioides brasiliensis Recognition by Human Plasmacytoid Dendritic Cells

(2018) Nycolas Willian Preite et al.   Frontiers in Immunology

C-Type Lectin Receptors in Antiviral Immunity and Viral Escape

(2018) Marta Bermejo-Jambrina et al.   Frontiers in Immunology

Dectin-1 Positive Dendritic Cells Expand after Infection with Leishmania major Parasites and Represent Promising Targets for Vaccine Development

(2018) Nicole Zimara et al.   Frontiers in Immunology

Regulation of C-Type Lectin Receptor-Mediated Antifungal Immunity

(2018) Juan Tang et al.   Frontiers in Immunology

Targeting the Mincle and TLR3 receptor using the dual agonist cationic adjuvant formulation 9 (CAF09) induces humoral and polyfunctional memory T cell responses in calves

(2018) Aneesh Thakur et al.   PLoS One

Gene Expression Response to Sea Lice in Atlantic Salmon Skin: RNA Sequencing Comparison Between Resistant and Susceptible Animals

(2018) Diego Robledo et al.   Frontiers in Genetics

DNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment

(2018) Carlos del Fresno et al.   SCIENCE

Mechanism of pathogen recognition by human dectin-2

(2017) Hadar Feinberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dectin-1 Activation duringLeishmania amazonensisPhagocytosis Prompts Syk-Dependent Reactive Oxygen Species Production To Trigger Inflammasome Assembly and Restriction of Parasite Replication

(2017) Djalma S. Lima-Junior et al.   JOURNAL OF IMMUNOLOGY

Contact, Collaboration, and Conflict: Signal Integration of Syk-Coupled C-Type Lectin Receptors

(2017) Jenny Ostrop et al.   JOURNAL OF IMMUNOLOGY

Helminth glycomics – glycan repertoires and host-parasite interactions

(2017) Cornelis H. Hokke et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Immune transcriptome reveals the mincle C-type lectin receptor acts as a partial replacement for TLR4 in lipopolysaccharide-mediated inflammatory response in barramundi ( Lates calcarifer )

(2017) Emmanuelle Zoccola et al.   MOLECULAR IMMUNOLOGY

Genome-wide association analysis in dogs implicates 99 loci as risk variants for anterior cruciate ligament rupture

(2017) Lauren A. Baker et al.   PLoS One

Rational design of adjuvants targeting the C-type lectin Mincle

(2017) Alexiane Decout et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of C-type lectin receptors and Toll-like receptors in decidua of patients with unexplained recurrent spontaneous abortion

(2017) Liang Xu et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Targeting antigens to Dec-205 on dendritic cells induces a higher immune response in chickens: Hemagglutinin of avian influenza virus example

(2017) David Jáuregui-Zúñiga et al.   RESEARCH IN VETERINARY SCIENCE

Mite allergoids coupled to nonoxidized mannan from Saccharomyces cerevisae efficiently target canine dendritic cells for novel allergy immunotherapy in veterinary medicine

(2017) Irene Soria et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Myeloid C-Type Lectin Receptors in Viral Recognition and Antiviral Immunity

(2017) João Monteiro et al.   Viruses-Basel

Dectin-1 Compromises Innate Responses and Host Resistance against Neospora caninum Infection

(2017) Murilo Vieira da Silva et al.   Frontiers in Immunology

Fasciola hepatica glycoconjugates immuneregulate dendritic cells through the Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin inducing T cell anergy

(2017) Ernesto Rodríguez et al.   Scientific Reports

Identification and expression modulation of a C-type lectin domain family 4 homologue that is highly expressed in monocytes/macrophages in rainbow trout (Oncorhynchus mykiss)

(2016) Petronella Johansson et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Recognition of purified beta 1,3/1,6 glucan and molecular signalling in the intestine of Atlantic salmon

(2016) Viswanath Kiron et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Galectins: their network and roles in immunity/tumor growth control

(2016) Herbert Kaltner et al.   HISTOCHEMISTRY AND CELL BIOLOGY

C-type lectins: their network and roles in pathogen recognition and immunity

(2016) Sabine Mayer et al.   HISTOCHEMISTRY AND CELL BIOLOGY

C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection

(2016) Kenji Toyonaga et al.   IMMUNITY

Polymorphisms of the immune-modulating receptor dectin-1 in pigs: their functional influence and distribution in pig populations

(2016) Hiroki Shinkai et al.   IMMUNOGENETICS

Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent

(2016) Jonas Hanske et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Broilers with low serum Mannose-binding Lectin show increased fecal shedding ofSalmonella entericaserovar Montevideo

(2016) Sofie L. Ulrich-Lynge et al.   POULTRY SCIENCE

The innate immune receptor Dectin-2 mediates the phagocytosis of cancer cells by Kupffer cells for the suppression of liver metastasis

(2016) Yoshitaka Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C-type lectins facilitate tumor metastasis

(2016) Dongbing Ding et al.   Oncology Letters

Recombinant Forms of Leishmania amazonensis Excreted/Secreted Promastigote Surface Antigen (PSA) Induce Protective Immune Responses in Dogs

(2016) Elodie Petitdidier et al.   PLoS Neglected Tropical Diseases

Mechanistic Insights into the Role of C-Type Lectin Receptor/CARD9 Signaling in Human Antifungal Immunity

(2016) Rebecca A. Drummond et al.   Frontiers in Cellular and Infection Microbiology

Inhibition of TREM-1 and Dectin-1 Alleviates the Severity of Fungal Keratitis by Modulating Innate Immune Responses

(2016) Jing Zhong et al.   PLoS One

The Prefrontal Dectin-1/AMPA Receptor Signaling Pathway Mediates The Robust and Prolonged Antidepressant Effect of Proteo-β-Glucan from Maitake

(2016) Hongkun Bao et al.   Scientific Reports

MICL controls inflammation in rheumatoid arthritis

(2015) Pierre Redelinghuys et al.   ANNALS OF THE RHEUMATIC DISEASES

The C-Type Lectin Receptor CLECSF8/CLEC4D Is a Key Component of Anti-Mycobacterial Immunity

(2015) Gillian J. Wilson et al.   Cell Host & Microbe

Mycobacterium tuberculosis β-gentiobiosyl diacylglycerides signal through the pattern recognition receptor Mincle: total synthesis and structure activity relationships

(2015) Mark B. Richardson et al.   CHEMICAL COMMUNICATIONS

C-type lectins in immunity: recent developments

(2015) Ivy M Dambuza et al.   CURRENT OPINION IN IMMUNOLOGY

Recent insights into structures and functions of C-type lectins in the immune system

(2015) Kurt Drickamer et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Cell type-specific differences in β-glucan recognition and signalling in porcine innate immune cells

(2015) Kim Baert et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Human Mincle Binds to Cholesterol Crystals and Triggers Innate Immune Responses

(2015) Ryoko Kiyotake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C-Type Lectin Receptor MCL Facilitates Mincle Expression and Signaling through Complex Formation

(2015) Yasunobu Miyake et al.   JOURNAL OF IMMUNOLOGY

Comparison of innate and Th1-type host immune responses inOesophagostomum dentatumandTrichuris suisinfections in pigs

(2015) A. Andreasen et al.   PARASITE IMMUNOLOGY

Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells

(2015) Jin Li et al.   Nature Communications

Mincle, an Innate Immune Receptor, Is Expressed in Urothelial Cancer Cells of Papillomavirus-Associated Urothelial Tumors of Cattle

(2015) Sante Roperto et al.   PLoS One

Comparative transcriptomics of Atlantic Salmo salar, chum Oncorhynchus keta and pink salmon O. gorbuscha during infections with salmon lice Lepeophtheirus salmonis

(2014) Ben JG Sutherland et al.   BMC GENOMICS

Bovine CLEC7A genetic variants and their association with seropositivity in Johne's disease ELISA

(2014) S.D. Pant et al.   GENE

Clec12a Is an Inhibitory Receptor for Uric Acid Crystals that Regulates Inflammation in Response to Cell Death

(2014) Konstantin Neumann et al.   IMMUNITY

Glycerol Monomycolate Is a Novel Ligand for the Human, but Not Mouse Macrophage Inducible C-type Lectin, Mincle

(2014) Yuki Hattori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis-specific T-cell responses in human

(2014) Jaap T. van Dissel et al.   VACCINE

Identification of Distinct Ligands for the C-type Lectin Receptors Mincle and Dectin-2 in the Pathogenic Fungus Malassezia

(2013) Tetsuaki Ishikawa et al.   Cell Host & Microbe

A platform to screen for C-type lectin receptor-binding carbohydrates and their potential for cell-specific targeting and immune modulation

(2013) Maha Maglinao et al.   JOURNAL OF CONTROLLED RELEASE

The C-Type Lectin Receptor DCIR Is Crucial for the Development of Experimental Cerebral Malaria

(2013) M. Maglinao et al.   JOURNAL OF IMMUNOLOGY

Parasitic Infections: A Role for C-Type Lectins Receptors

(2013) Alicia Vázquez-Mendoza et al.   Biomed Research International

Signaling by Myeloid C-Type Lectin Receptors in Immunity and Homeostasis

(2012) David Sancho et al.   Annual Review of Immunology

Trichuris suis-induced modulation of human dendritic cell function is glycan-mediated

(2012) Elsenoor J. Klaver et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Expression of the C-type lectins DC-SIGN or L-SIGN alters host cell susceptibility for the avian coronavirus, infectious bronchitis virus

(2012) Yueting Zhang et al.   VETERINARY MICROBIOLOGY

DC-SIGN as a Receptor for Phleboviruses

(2011) Pierre-Yves Lozach et al.   Cell Host & Microbe

Targeting Syk-Card9-activating C-type lectin receptors by vaccine adjuvants: Findings, implications and open questions

(2011) Roland Lang et al.   IMMUNOBIOLOGY

CAF01 Potentiates Immune Responses and Efficacy of an Inactivated Influenza Vaccine in Ferrets

(2011) Cyril Jean-Marie Martel et al.   PLoS One

Polymorphisms in mannose-binding lectin (MBL) gene and their association with MBL protein levels in serum in the Hu sheep

(2011) Feng Zhao et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity

(2010) C. Cunha et al.   BLOOD

Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate

(2010) H. Schoenen et al.   JOURNAL OF IMMUNOLOGY

Feline Lectin Activity Is Critical for the Cellular Entry of Feline Infectious Peritonitis Virus

(2010) A. D. Regan et al.   JOURNAL OF VIROLOGY

Early Stop Polymorphism in Human DECTIN‐1 Is Associated with IncreasedCandidaColonization in Hematopoietic Stem Cell Transplant Recipients

(2009) Theo S. Plantinga et al.   CLINICAL INFECTIOUS DISEASES

Glycan gimmickry by parasitic helminths: A strategy for modulating the host immune response?

(2009) I. van Die et al.   GLYCOBIOLOGY

Endogenous ligands for C-type lectin receptors: the true regulators of immune homeostasis

(2009) Juan J. García-Vallejo et al.   IMMUNOLOGICAL REVIEWS

β-glucan recognition by the innate immune system

(2009) Helen S. Goodridge et al.   IMMUNOLOGICAL REVIEWS

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

(2009) Eri Ishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of murine MGL1 and MGL2 C-type lectins: Distinct glycan specificities and tumor binding properties

(2009) Satwinder Kaur Singh et al.   MOLECULAR IMMUNOLOGY

Discovery of candidate genes and pathways in the endometrium regulating ovine blastocyst growth and conceptus elongation

(2009) M. Carey Satterfield et al.   PHYSIOLOGICAL GENOMICS

Protein-glycan interactions in the control of innate and adaptive immune responses

(2008) Yvette van Kooyk et al.   NATURE IMMUNOLOGY

The selective Dectin-1 agonist, curdlan, induces an oxidative burst response in chicken heterophils and peripheral blood mononuclear cells

(2008) Jessica R. Nerren et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY