Impaired ECM Remodeling and Macrophage Activity Define Necrosis and Regeneration Following Damage in Aged Skeletal Muscle

Age‐related changes to the satellite cell niche are associated with reduced activation following exercise

(2020) Joshua P. Nederveen et al.   FASEB JOURNAL

Adiponectin promotes muscle regeneration through binding to T-cadherin

(2019) Yoshimitsu Tanaka et al.   Scientific Reports

Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors

(2019) Laura Lukjanenko et al.   Cell Stem Cell

Skewed macrophage polarization in aging skeletal muscle

(2019) Chang‐Yi Cui et al.   AGING CELL

Cross-talk between TGF-β and PDGFRα signaling pathways regulates the fate of stromal fibro–adipogenic progenitors

(2019) Osvaldo Contreras et al.   JOURNAL OF CELL SCIENCE

Musculoskeletal senescence: a moving target ready to be eliminated

(2018) Marjolein P Baar et al.   CURRENT OPINION IN PHARMACOLOGY

Associations of Muscle Mass and Strength with All-Cause Mortality among US Older Adults

(2018) RAN LI et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Expression, Intracellular Localization, and Prognostic Value of Plasminogen Activator Inhibitor 1 and PAI-1 RNA-Binding Protein 1 in Primary and Recurrent Ovarian Cancer: A Study of the Tumor Bank Ovarian Cancer Network

(2017) Dominique Koensgen et al.   GYNECOLOGIC AND OBSTETRIC INVESTIGATION

Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis

(2016) Osvaldo Contreras et al.   CELL AND TISSUE RESEARCH

Influence of exercise and aging on extracellular matrix composition in the skeletal muscle stem cell niche

(2016) Koyal Garg et al.   JOURNAL OF APPLIED PHYSIOLOGY

Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice

(2016) Laura Lukjanenko et al.   NATURE MEDICINE

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Effects of testosterone on lean mass gain in elderly men: systematic review with meta-analysis of controlled and randomized studies

(2015) Walter Krause Neto et al.   AGE

Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake

(2015) Adam P. Sharples et al.   AGING CELL

Increases of M2a macrophages and fibrosis in aging muscle are influenced by bone marrow aging and negatively regulated by muscle-derived nitric oxide

(2015) Ying Wang et al.   AGING CELL

Protein intake and muscle function in older adults

(2015) Rachel R. Deer et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation

(2015) Cynthia Dayer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors

(2015) Dario R Lemos et al.   NATURE MEDICINE

The central role of muscle stem cells in regenerative failure with aging

(2015) Helen M Blau et al.   NATURE MEDICINE

Increased Stiffness in Aged Skeletal Muscle Impairs Muscle Progenitor Cell Proliferative Activity

(2015) Grégory Lacraz et al.   PLoS One

Extracellular matrix regulation in the muscle satellite cell niche

(2014) Kelsey Thomas et al.   CONNECTIVE TISSUE RESEARCH

Age and aerobic training status effects on plasma and skeletal muscle tPA and PAI-1

(2014) Ryan M. Francis et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Sarcopenia, Cachexia and Aging: Diagnosis, Mechanisms and Therapeutic Options - A Mini-Review

(2014) Sumbul Ali et al.   GERONTOLOGY

Intrinsic stiffness of extracellular matrix increases with age in skeletal muscles of mice

(2014) Lauren K. Wood et al.   JOURNAL OF APPLIED PHYSIOLOGY

Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy

(2014) Sherry Dadgar et al.   JOURNAL OF CELL BIOLOGY

Plasminogen Activator Inhibitor-1 Is Involved in Impaired Bone Repair Associated with Diabetes in Female Mice

(2014) Li Mao et al.   PLoS One

PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice

(2014) M. Eren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Plasminogen Activator Inhibitor-1 in Senescence and Aging

(2014) Mesut Eren et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Plasminogen Activator Inhibitor-1 in Aging

(2014) Kyosuke Takeshita et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Assessing skeletal muscle mass: historical overview and state of the art

(2014) Steven B. Heymsfield et al.   Journal of Cachexia Sarcopenia and Muscle

Fibronectin Regulates Wnt7a Signaling and Satellite Cell Expansion

(2013) C. Florian Bentzinger et al.   Cell Stem Cell

The Role of Dietary Protein Intake in the Prevention of Sarcopenia of Aging

(2013) Jeannette M. Beasley et al.   NUTRITION IN CLINICAL PRACTICE

Impaired Macrophage and Satellite Cell Infiltration Occurs in a Muscle-Specific Fashion Following Injury in Diabetic Skeletal Muscle

(2013) Matthew P. Krause et al.   PLoS One

Low Macrophage Accumulation in Skeletal Muscle of Obese Type 2 Diabetics and Elderly Subjects

(2012) Charmaine S. Tam et al.   Obesity

Matrix Metalloprotease 9 Mediates Neutrophil Migration into the Airways in Response to Influenza Virus-Induced Toll-Like Receptor Signaling

(2012) Linda M. Bradley et al.   PLoS Pathogens

Inhibition of Plasminogen Activator Inhibitor-1 Restores Skeletal Muscle Regeneration in Untreated Type 1 Diabetic Mice

(2011) M. P. Krause et al.   DIABETES

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle

(2011) A. Uezumi et al.   JOURNAL OF CELL SCIENCE

Macrophage-Specific Expression of Urokinase-Type Plasminogen Activator Promotes Skeletal Muscle Regeneration

(2011) M. L. Novak et al.   JOURNAL OF IMMUNOLOGY

Aberrant repair and fibrosis development in skeletal muscle

(2011) Christopher J Mann et al.   Skeletal Muscle

Hepatocyte Growth Factor System in the Mouse Uterus: Variation Across the Estrous Cycle and Regulation by 17-Beta-Estradiol and Progesterone1

(2010) Xuan Zhang   BIOLOGY OF REPRODUCTION

REVIEW: Plasminogen Activator Inhibitor-1 (PAI-1): A Key Factor Linking Fibrinolysis and Age-Related Subclinical and Clinical Conditions

(2010) Matteo Cesari et al.   Cardiovascular Therapeutics

Consensus definition of sarcopenia, cachexia and pre-cachexia: Joint document elaborated by Special Interest Groups (SIG) “cachexia-anorexia in chronic wasting diseases” and “nutrition in geriatrics”

(2010) M. Muscaritoli et al.   CLINICAL NUTRITION

A transitional extracellular matrix instructs cell behavior during muscle regeneration

(2010) Sarah Calve et al.   DEVELOPMENTAL BIOLOGY

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

(2010) Akiyoshi Uezumi et al.   NATURE CELL BIOLOGY

Role of matrix metalloproteinases in skeletal muscle

(2010) Xiaoping Chen et al.   Cell Adhesion & Migration

Plasminogen Activator Inhibitor Type 1 Up-Regulation Is Associated with Skeletal Muscle Atrophy and Associated Fibrosis

(2009) Jasmin Naderi et al.   AMERICAN JOURNAL OF PATHOLOGY

Urokinase-type plasminogen activator increases hepatocyte growth factor activity required for skeletal muscle regeneration

(2009) T. H. Sisson et al.   BLOOD

PAI-1 and kidney fibrosis

(2009) Li-Jun Ma   Frontiers in Bioscience-Landmark

Cytokine and Cytokine-Like Inflammation Markers, Endothelial Dysfunction, and Imbalanced Coagulation in Development of Diabetes and Its Complications

(2009) Ronald B. Goldberg   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effects of an Oral Growth Hormone Secretagogue in Older Adults

(2009) Heidi K. White et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

(2008) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS

Transforming Growth Factor-β Requires Its Target Plasminogen Activator Inhibitor-1 for Cytostatic Activity

(2008) Roderik M. Kortlever et al.   JOURNAL OF BIOLOGICAL CHEMISTRY