Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner

RvE1 treatment prevents memory loss and neuroinflammation in the Ts65Dn mouse model of Down syndrome

(2020) Eric D. Hamlett et al.   GLIA

Emerging Mechanisms of Cardiovascular Protection for the Omega-3 Fatty Acid Eicosapentaenoic Acid

(2020) R. Preston Mason et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Leukocytes from obese individuals exhibit an impaired SPM signature

(2019) Cristina López-Vicario et al.   FASEB JOURNAL

12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat

(2019) Luiz Osório Leiria et al.   Cell Metabolism

Protectin DX ameliorates palmitate‐induced hepatic insulin resistance through AMPK / SIRT 1‐mediated modulation of fetuin‐A and SeP expression

(2019) Tae Woo Jung et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

EPA and DHA have divergent effects on serum triglycerides and lipogenesis, but similar effects on lipoprotein lipase activity: a randomized controlled trial

(2019) Shannon L Klingel et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Omega-3, omega-6, and total dietary polyunsaturated fat for prevention and treatment of type 2 diabetes mellitus: systematic review and meta-analysis of randomised controlled trials

(2019) Tracey J Brown et al.   BMJ-British Medical Journal

Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses

(2019) Patricia R. Souza et al.   CIRCULATION RESEARCH

Interactive effects of maternal and weaning high linoleic acid intake on hepatic lipid metabolism, oxylipins profile and hepatic steatosis in offspring

(2019) Justine Marchix et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

All n-3 PUFA are not the same: MD simulations reveal differences in membrane organization for EPA, DHA and DPA

(2018) Xiaoling Leng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Omega-6 fatty acids and inflammation

(2018) Jacqueline K. Innes et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks

(2018) Theingi Aung et al.   JAMA Cardiology

Function of Pro-Resolving Lipid Mediator Resolvin E1 in Type 2 Diabetes

(2018) Corneliu Sima et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Genetic variant in the 3′-untranslated region of the COX2 gene is associated with type 2 diabetes: A hospital-based case-control study

(2018) Cansu Ozbayer et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity

(2018) Wei Ying et al.   Cell Metabolism

Frontline Science: A reduction in DHA-derived mediators in male obesity contributes toward defects in select B cell subsets and circulating antibody

(2018) Miranda J. Crouch et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia

(2018) Deepak L. Bhatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Maresin 1 improves insulin sensitivity and attenuates adipose tissue inflammation in ob/ob and diet-induced obese mice

(2017) Leyre Martínez-Fernández et al.   FASEB JOURNAL

B Cell Activity Is Impaired in Human and Mouse Obesity and Is Responsive to an Essential Fatty Acid upon Murine Influenza Infection

(2017) Rasagna Kosaraju et al.   JOURNAL OF IMMUNOLOGY

Eicosapentaenoic acid regulates brown adipose tissue metabolism in high-fat-fed mice and in clonal brown adipocytes

(2017) Mandana Pahlavani et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Association of a variant in the gene encoding for ERV1/ChemR23 with reduced inflammation in visceral adipose tissue from morbidly obese individuals

(2017) Cristina López-Vicario et al.   Scientific Reports

ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance

(2017) Corneliu Sima et al.   Scientific Reports

Polyunsaturated fatty acids and type 2 diabetes: Impact on the glycemic control mechanism

(2016) Olívia Gonçalves Leão Coelho et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Neutrophil Resolvin E1 Receptor Expression and Function in Type 2 Diabetes

(2016) Marcelo O. Freire et al.   JOURNAL OF IMMUNOLOGY

Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue

(2016) Esther Titos et al.   JOURNAL OF IMMUNOLOGY

EPA prevents fat mass expansion and metabolic disturbances in mice fed with a Western diet

(2016) Alexandre Pinel et al.   JOURNAL OF LIPID RESEARCH

Arachidonate 5-lipoxygenase (ALOX5) gene polymorphism is associated with Alzheimer's disease and body mass index

(2016) Omar Šerý et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Global survey of the omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid in the blood stream of healthy adults

(2016) Ken D. Stark et al.   PROGRESS IN LIPID RESEARCH

Linoleic acid and the pathogenesis of obesity

(2016) Shaan S. Naughton et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Insulin-Sensitizing Effects of Omega-3 Fatty Acids: Lost in Translation?

(2016) Antigoni Lalia et al.   Nutrients

Update on NHANES Dietary Data: Focus on Collection, Release, Analytical Considerations, and Uses to Inform Public Policy

(2016) Namanjeet Ahluwalia et al.   Advances in Nutrition

Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

(2015) Robert Caesar et al.   Cell Metabolism

LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes

(2015) Pingping Li et al.   NATURE MEDICINE

Impact of Resolvin E1 on Murine Neutrophil Phagocytosis in Type 2 Diabetes

(2014) Bruno S. Herrera et al.   INFECTION AND IMMUNITY

Chemerin/chemR23 axis in inflammation onset and resolution

(2014) Francesco Mariani et al.   INFLAMMATION RESEARCH

Eicosapentaenoic and docosahexaenoic acid ethyl esters differentially enhance B-cell activity in murine obesity

(2014) Heather Teague et al.   JOURNAL OF LIPID RESEARCH

Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis

(2014) Phillip J White et al.   NATURE MEDICINE

Transient and Persistent Metabolomic Changes in Plasma following Chronic Cigarette Smoke Exposure in a Mouse Model

(2014) Charmion I. Cruickshank-Quinn et al.   PLoS One

Linoleic acid: Between doubts and certainties

(2013) Benjamin Choque et al.   BIOCHIMIE

Impaired Local Production of Proresolving Lipid Mediators in Obesity and 17-HDHA as a Potential Treatment for Obesity-Associated Inflammation

(2013) A. Neuhofer et al.   DIABETES

New sample preparation approach for mass spectrometry-based profiling of plasma results in improved coverage of metabolome

(2013) Yanhui Yang et al.   JOURNAL OF CHROMATOGRAPHY A

Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaques

(2012) Timo Frömel et al.   BASIC RESEARCH IN CARDIOLOGY

Proresolution Therapy for the Treatment of Delayed Healing of Diabetic Wounds

(2012) Y. Tang et al.   DIABETES

Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat

(2012) J. Claria et al.   JOURNAL OF IMMUNOLOGY

PPARγ as a molecular target of EPA anti-inflammatory activity during TNF-α-impaired skeletal muscle cell differentiation

(2012) Peter Magee et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The diversity outbred mouse population

(2012) Gary A. Churchill et al.   MAMMALIAN GENOME

Resolvin D1 decreases adipose tissue macrophage accumulation and improves insulin sensitivity in obese-diabetic mice

(2011) Jason Hellmann et al.   FASEB JOURNAL

CYP-eicosanoids—A new link between omega-3 fatty acids and cardiac disease?

(2011) Christina Westphal et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat-Fed Mice

(2010) P. J. White et al.   DIABETES

Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification

(2010) E. L. Campbell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obesity-induced insulin resistance and hepatic steatosis are alleviated by ω-3 fatty acids: a role for resolvins and protectins

(2009) Ana González-Périz et al.   FASEB JOURNAL

Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis

(2009) David R. Crosslin et al.   HUMAN GENETICS

Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450

(2008) Maude Fer et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS