Microtubules pull the strings: disordered sequences as efficient couplers of microtubule-generated force

Mechanisms of Motor-Independent Membrane Remodeling Driven by Dynamic Microtubules

(2020) Ruddi Rodríguez-García et al.   CURRENT BIOLOGY

CENP-F stabilizes kinetochore-microtubule attachments and limits dynein stripping of corona cargoes

(2020) Philip Auckland et al.   JOURNAL OF CELL BIOLOGY

Bistability and oscillations in cooperative microtubule and kinetochore dynamics in the mitotic spindle

(2020) Felix Schwietert et al.   NEW JOURNAL OF PHYSICS

Miro-dependent mitochondrial pool of CENP-F and its farnesylated C-terminal domain are dispensable for normal development in mice

(2019) Martin Peterka et al.   PLoS Genetics

Regulation of MT dynamics via direct binding of an Abl family kinase

(2019) Yuhan Hu et al.   JOURNAL OF CELL BIOLOGY

Multivalent electrostatic microtubule interactions of synthetic peptides are sufficient to mimic advanced MAP-like behavior

(2019) Hauke Drechsler et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling

(2019) Pim J Huis in 't Veld et al.   eLife

CLASP Suppresses Microtubule Catastrophes through a Single TOG Domain

(2018) Amol Aher et al.   DEVELOPMENTAL CELL

Disentangling the molecular determinants for Cenp‐F localization to nuclear pores and kinetochores

(2018) Alessandro Berto et al.   EMBO REPORTS

The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases

(2018) Giuseppe Ciossani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microtubules grow by the addition of bent guanosine triphosphate tubulin to the tips of curved protofilaments

(2018) J. Richard McIntosh et al.   JOURNAL OF CELL BIOLOGY

Microtubule dynamics: an interplay of biochemistry and mechanics

(2018) Gary J. Brouhard et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human Ska complex and Ndc80 complex interact to form a load-bearing assembly that strengthens kinetochore–microtubule attachments

(2018) Luke A. Helgeson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Separating the effects of nucleotide and EB binding on microtubule structure

(2018) Rui Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the DASH/Dam1 complex shows its role at the yeast kinetochore-microtubule interface

(2018) Simon Jenni et al.   SCIENCE

Multivalency of NDC80 in the outer kinetochore is essential to track shortening microtubules and generate forces

(2018) Vladimir A Volkov et al.   eLife

The kinetoplastid kinetochore protein KKT4 is an unconventional microtubule tip–coupling protein

(2018) Aida Llauró et al.   JOURNAL OF CELL BIOLOGY

Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80

(2018) Marion E. Pesenti et al.   MOLECULAR CELL

Visualizing Intracellular Organelle and Cytoskeletal Interactions at Nanoscale Resolution on Millisecond Timescales

(2018) Yuting Guo et al.   CELL

Unique Phylogenetic Distributions of the Ska and Dam1 Complexes Support Functional Analogy and Suggest Multiple Parallel Displacements of Ska by Dam1

(2017) Jolien J. E. van Hooff et al.   Genome Biology and Evolution

CENP-F couples cargo to growing and shortening microtubule ends

(2017) Gil Kanfer et al.   MOLECULAR BIOLOGY OF THE CELL

A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments

(2016) Matthew P. Miller et al.   CELL

The Ska complex promotes Aurora B activity to ensure chromosome biorientation

(2016) Patrick M. Redli et al.   JOURNAL OF CELL BIOLOGY

Understanding force-generating microtubule systems through in vitro reconstitution

(2016) Mathijs Vleugel et al.   Cell Adhesion & Migration

Molecular architecture of the Dam1 complex–microtubule interaction

(2016) Thibault Legal et al.   Open Biology

Ska3 Ensures Timely Mitotic Progression by Interacting Directly With Microtubules and Ska1 Microtubule Binding Domain

(2016) Maria Alba Abad et al.   Scientific Reports

Centromere protein F includes two sites that couple efficiently to depolymerizing microtubules

(2015) Vladimir A. Volkov et al.   JOURNAL OF CELL BIOLOGY

Multisite phosphorylation of the NDC80 complex gradually tunes its microtubule-binding affinity

(2015) Anatoly V. Zaytsev et al.   MOLECULAR BIOLOGY OF THE CELL

Mitotic redistribution of the mitochondrial network by Miro and Cenp-F

(2015) Gil Kanfer et al.   Nature Communications

DISOPRED3: precise disordered region predictions with annotated protein-binding activity

(2014) David T. Jones et al.   BIOINFORMATICS

Discovery of Unconventional Kinetochores in Kinetoplastids

(2014) Bungo Akiyoshi et al.   CELL

Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin

(2014) Ulrike Engel et al.   Cytoskeleton

Kinetochore Biorientation in Saccharomyces cerevisiae Requires a Tightly Folded Conformation of the Ndc80 Complex

(2014) Jerry F. Tien et al.   GENETICS

Stu2, the Budding Yeast XMAP215/Dis1 Homolog, Promotes Assembly of Yeast Microtubules by Increasing Growth Rate and Decreasing Catastrophe Frequency

(2014) Marija Podolski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for microtubule recognition by the human kinetochore Ska complex

(2014) Maria Alba Abad et al.   Nature Communications

Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation

(2014) Neil T. Umbreit et al.   Nature Communications

The Microtubule Binding Properties of CENP-E's C-Terminus and CENP-F

(2013) Vivek Musinipally et al.   JOURNAL OF MOLECULAR BIOLOGY

Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips

(2013) Nikita Gudimchuk et al.   NATURE CELL BIOLOGY

Forces due to curving protofilaments in microtubules

(2013) Shirish Vichare et al.   PHYSICAL REVIEW E

Long tethers provide high-force coupling of the Dam1 ring to shortening microtubules

(2013) V. A. Volkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The growth speed of microtubules with XMAP215-coated beads coupled to their ends is increased by tensile force

(2013) Anastasiya Trushko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Kinetochore-Bound Ska1 Complex Tracks Depolymerizing Microtubules and Binds to Curved Protofilaments

(2012) Jens C. Schmidt et al.   DEVELOPMENTAL CELL

Multimodal microtubule binding by the Ndc80 kinetochore complex

(2012) Gregory M Alushin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evolution and disorder

(2011) Celeste J Brown et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Subunit organization in the Dam1 kinetochore complex and its ring around microtubules

(2011) Vincent H. Ramey et al.   MOLECULAR BIOLOGY OF THE CELL

XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region

(2011) P. O. Widlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CLASP Promotes Microtubule Rescue by Recruiting Tubulin Dimers to the Microtubule

(2010) Jawdat Al-Bassam et al.   DEVELOPMENTAL CELL

The Dam1 complex confers microtubule plus end–tracking activity to the Ndc80 kinetochore complex

(2010) Fabienne Lampert et al.   JOURNAL OF CELL BIOLOGY

Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B

(2010) Jerry F. Tien et al.   JOURNAL OF CELL BIOLOGY

Tubulin depolymerization may be an ancient biological motor

(2010) J. R. McIntosh et al.   JOURNAL OF CELL SCIENCE

The Dam1 ring binds to the E-hook of tubulin and diffuses along the microtubule

(2010) Vincent H. Ramey et al.   MOLECULAR BIOLOGY OF THE CELL

Tension directly stabilizes reconstituted kinetochore-microtubule attachments

(2010) Bungo Akiyoshi et al.   NATURE

Kinetochores’ gripping feat: conformational wave or biased diffusion?

(2010) Charles L. Asbury et al.   TRENDS IN CELL BIOLOGY

The Ndc80 Kinetochore Complex Forms Load-Bearing Attachments to Dynamic Microtubule Tips via Biased Diffusion

(2009) Andrew F. Powers et al.   CELL

The Human Kinetochore Ska1 Complex Facilitates Microtubule Depolymerization-Coupled Motility

(2009) Julie P.I. Welburn et al.   DEVELOPMENTAL CELL

RAMA1 is a novel kinetochore protein involved in kinetochore-microtubule attachment

(2009) J. A. Raaijmakers et al.   JOURNAL OF CELL SCIENCE

Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex

(2008) Claudio Ciferri et al.   CELL

XMAP215 Is a Processive Microtubule Polymerase

(2008) Gary J. Brouhard et al.   CELL

Fibrils Connect Microtubule Tips with Kinetochores: A Mechanism to Couple Tubulin Dynamics to Chromosome Motion

(2008) J. Richard McIntosh et al.   CELL

Kinetochore-Microtubule Attachment Relies on the Disordered N-Terminal Tail Domain of Hec1

(2008) Geoffrey J. Guimaraes et al.   CURRENT BIOLOGY

Kinetochore Attachments Require an Interaction between Unstructured Tails on Microtubules and Ndc80Hec1

(2008) Stephanie A. Miller et al.   CURRENT BIOLOGY

Function and structure of inherently disordered proteins

(2008) A Keith Dunker et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Different assemblies of the DAM1 complex follow shortening microtubules by distinct mechanisms

(2008) E. L. Grishchuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Dam1 ring binds microtubules strongly enough to be a processive as well as energy-efficient coupler for chromosome motion

(2008) E. L. Grishchuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA