Multivalency of NDC80 in the outer kinetochore is essential to track shortening microtubules and generate forces

Human Ska complex and Ndc80 complex interact to form a load-bearing assembly that strengthens kinetochore–microtubule attachments

(2018) Luke A. Helgeson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments

(2016) Matthew P. Miller et al.   CELL

Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores

(2016) Arsen Petrovic et al.   CELL

Insights from biochemical reconstitution into the architecture of human kinetochores

(2016) John R. Weir et al.   NATURE

biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes

(2016) Florian Weissmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phase separation of signaling molecules promotes T cell receptor signal transduction

(2016) Xiaolei Su et al.   SCIENCE

Molecular basis of outer kinetochore assembly on CENP-T

(2016) Pim J Huis in 't Veld et al.   eLife

Ca2+-independent sortase-A exhibits high selective protein ligation activity in the cytoplasm ofEscherichia coli

(2015) Hidehiko Hirakawa et al.   Biotechnology Journal

Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores

(2015) Soonjoung Kim et al.   JOURNAL OF CELL BIOLOGY

Multisite phosphorylation of the NDC80 complex gradually tunes its microtubule-binding affinity

(2015) Anatoly V. Zaytsev et al.   MOLECULAR BIOLOGY OF THE CELL

A quantitative description of Ndc80 complex linkage to human kinetochores

(2015) Aussie Suzuki et al.   Nature Communications

Ca2+-independent sortase-A exhibits high selective protein ligation activity in the cytoplasm ofEscherichia coli

(2015) Hidehiko Hirakawa et al.   Biotechnology Journal

SpyAvidin Hubs Enable Precise and Ultrastable Orthogonal Nanoassembly

(2014) Michael Fairhead et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sister kinetochores are mechanically fused during meiosis I in yeast

(2014) K. K. Sarangapani et al.   SCIENCE

Phase transitions of multivalent proteins can promote clustering of membrane receptors

(2014) Sudeep Banjade et al.   eLife

Preparation of Segmented Microtubules to Study Motions Driven by the Disassembling Microtubule Ends

(2014) Vladimir A. Volkov et al.   Jove-Journal of Visualized Experiments

A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors

(2013) Francesca Malvezzi et al.   EMBO JOURNAL

Elevated polar ejection forces stabilize kinetochore–microtubule attachments

(2013) Stuart Cane et al.   JOURNAL OF CELL BIOLOGY

Forces due to curving protofilaments in microtubules

(2013) Shirish Vichare et al.   PHYSICAL REVIEW E

Long tethers provide high-force coupling of the Dam1 ring to shortening microtubules

(2013) V. A. Volkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CENP-T-W-S-X Forms a Unique Centromeric Chromatin Structure with a Histone-like Fold

(2012) Tatsuya Nishino et al.   CELL

The Kinetochore-Bound Ska1 Complex Tracks Depolymerizing Microtubules and Binds to Curved Protofilaments

(2012) Jens C. Schmidt et al.   DEVELOPMENTAL CELL

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The Ndc80 kinetochore complex directly modulates microtubule dynamics

(2012) N. T. Umbreit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

(2012) B. Zakeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NoRSE: noise reduction and state evaluator for high-frequency single event traces

(2011) Nigel F. Reuel et al.   BIOINFORMATICS

Induced Ectopic Kinetochore Assembly Bypasses the Requirement for CENP-A Nucleosomes

(2011) Karen E. Gascoigne et al.   CELL

Direct Binding of Cenp-C to the Mis12 Complex Joins the Inner and Outer Kinetochore

(2011) Emanuela Screpanti et al.   CURRENT BIOLOGY

CENP-C Is a Structural Platform for Kinetochore Assembly

(2011) Marcin R. Przewloka et al.   CURRENT BIOLOGY

The Dam1 complex confers microtubule plus end–tracking activity to the Ndc80 kinetochore complex

(2010) Fabienne Lampert et al.   JOURNAL OF CELL BIOLOGY

Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B

(2010) Jerry F. Tien et al.   JOURNAL OF CELL BIOLOGY

Tension directly stabilizes reconstituted kinetochore-microtubule attachments

(2010) Bungo Akiyoshi et al.   NATURE

The Ndc80 kinetochore complex forms oligomeric arrays along microtubules

(2010) Gregory M. Alushin et al.   NATURE

A streptavidin variant with slower biotin dissociation and increased mechanostability

(2010) Claire E Chivers et al.   NATURE METHODS

Kinetochores’ gripping feat: conformational wave or biased diffusion?

(2010) Charles L. Asbury et al.   TRENDS IN CELL BIOLOGY

The Ndc80 Kinetochore Complex Forms Load-Bearing Attachments to Dynamic Microtubule Tips via Biased Diffusion

(2009) Andrew F. Powers et al.   CELL

The Human Kinetochore Ska1 Complex Facilitates Microtubule Depolymerization-Coupled Motility

(2009) Julie P.I. Welburn et al.   DEVELOPMENTAL CELL

Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex

(2008) Claudio Ciferri et al.   CELL

Fibrils Connect Microtubule Tips with Kinetochores: A Mechanism to Couple Tubulin Dynamics to Chromosome Motion

(2008) J. Richard McIntosh et al.   CELL

The Dam1 ring binds microtubules strongly enough to be a processive as well as energy-efficient coupler for chromosome motion

(2008) E. L. Grishchuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA