Cell death in animal development

Autophagy in animal development

(2020) Elizabeth A. Allen et al.   CELL DEATH AND DIFFERENTIATION

Entosis Controls a Developmental Cell Clearance in C. elegans

(2019) Yongchan Lee et al.   Cell Reports

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

Cell elimination strategies upon identity switch via modulation of apterous in Drosophila wing disc

(2019) Olga Klipa et al.   PLoS Genetics

Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK

(2018) Francine F.S. Ke et al.   CELL

EFF-1 fusogen promotes phagosome sealing during cell process clearance in Caenorhabditis elegans

(2018) Piya Ghose et al.   NATURE CELL BIOLOGY

Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion

(2018) Anna Gorelick-Ashkenazi et al.   Nature Communications

RAB-35 and ARF-6 GTPases Mediate Engulfment and Clearance Following Linker Cell-Type Death

(2018) Lena M. Kutscher et al.   DEVELOPMENTAL CELL

miRNAs cooperate in apoptosis regulation duringC. elegansdevelopment

(2017) Ryan Sherrard et al.   GENES & DEVELOPMENT

Ferroptosis: bug or feature?

(2017) Scott J. Dixon   IMMUNOLOGICAL REVIEWS

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Both the apoptotic suicide pathway and phagocytosis are required for a programmed cell death in Caenorhabditis elegans

(2016) Holly L. Johnsen et al.   BMC BIOLOGY

Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling

(2016) David J. Simon et al.   CELL

Transcriptional control of non-apoptotic developmental cell death in C. elegans

(2016) Jennifer A Malin et al.   CELL DEATH AND DIFFERENTIATION

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Mechanisms and consequences of entosis

(2016) Shefali Krishna et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Control of non-apoptotic nurse cell death by engulfment genes in Drosophila

(2016) Allison K. Timmons et al.   FLY

Post-transcriptional control of executioner caspases by RNA-binding proteins

(2016) Deni Subasic et al.   GENES & DEVELOPMENT

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Mitochondrial Permeability Transition: New Findings and Persisting Uncertainties

(2016) Valentina Izzo et al.   TRENDS IN CELL BIOLOGY

HSF-1 activates the ubiquitin proteasome system to promote non-apoptotic developmental cell death in C. elegans

(2016) Maxime J Kinet et al.   eLife

Cell death and morphogenesis during early mouse development: Are they interconnected?

(2015) Ivan Bedzhov et al.   BIOESSAYS

Pyroptotic cell death defends against intracellular pathogens

(2015) Ine Jorgensen et al.   IMMUNOLOGICAL REVIEWS

Phagocytosis of apoptotic cells in homeostasis

(2015) Sanja Arandjelovic et al.   NATURE IMMUNOLOGY

Multifaceted roles of HSF1 in cancer

(2015) Sufang Jiang et al.   TUMOR BIOLOGY

Engulfment pathways promote programmed cell death by enhancing the unequal segregation of apoptotic potential

(2015) Sayantan Chakraborty et al.   Nature Communications

Axon and dendrite pruning in Drosophila

(2014) Fengwei Yu et al.   CURRENT OPINION IN NEUROBIOLOGY

Regulated necrosis: the expanding network of non-apoptotic cell death pathways

(2014) Tom Vanden Berghe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Necroptosis

(2014) Andreas Linkermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Molecular mechanisms of regulated necrosis

(2014) Lorenzo Galluzzi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities

(2013) Amos A Fatokun et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection

(2013) Youssef Aachoui et al.   CURRENT OPINION IN MICROBIOLOGY

Alternative Germ Cell Death Pathway in Drosophila Involves HtrA2/Omi, Lysosomes, and a Caspase-9 Counterpart

(2013) Keren Yacobi-Sharon et al.   DEVELOPMENTAL CELL

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

(2013) James M. Murphy et al.   IMMUNITY

Poly(ADP-ribose) signaling in cell death

(2013) László Virág et al.   MOLECULAR ASPECTS OF MEDICINE

Combined Inhibition of Autophagy and Caspases Fails to Prevent Developmental Nurse Cell Death in the Drosophila melanogaster Ovary

(2013) Jeanne S. Peterson et al.   PLoS One

Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells

(2013) J. Suzuki et al.   SCIENCE

Diversity of cell death pathways: insight from the fly ovary

(2013) Victoria K. Jenkins et al.   TRENDS IN CELL BIOLOGY

Both the Caspase CSP-1 and a Caspase-Independent Pathway Promote Programmed Cell Death in Parallel to the Canonical Pathway for Apoptosis in Caenorhabditis elegans

(2013) Daniel P. Denning et al.   PLoS Genetics

Drosophila larvae lacking the bcl-2 gene, buffy, are sensitive to nutrient stress, maintain increased basal target of rapamycin (Tor) signaling and exhibit characteristics of altered basal energy metabolism

(2012) Jessica P Monserrate et al.   BMC BIOLOGY

Caspase-14-Deficient Mice Are More Prone to the Development of Parakeratosis

(2012) Esther Hoste et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Spatially Coordinated Kinase Signaling Regulates Local Axon Degeneration

(2012) M. Chen et al.   JOURNAL OF NEUROSCIENCE

A Caspase Cascade Regulating Developmental Axon Degeneration

(2012) D. J. Simon et al.   JOURNAL OF NEUROSCIENCE

Programmed elimination of cells by caspase-independent cell extrusion in C. elegans

(2012) Daniel P. Denning et al.   NATURE

dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway

(2012) J. M. Osterloh et al.   SCIENCE

Control of Nonapoptotic Developmental Cell Death in Caenorhabditis elegans by a Polyglutamine-Repeat Protein

(2012) E. S. Blum et al.   SCIENCE

The Highwire Ubiquitin Ligase Promotes Axonal Degeneration by Tuning Levels of Nmnat Protein

(2012) Xin Xiong et al.   PLOS BIOLOGY

Redistribution of the tight junction protein ZO-1 during physiological shedding of mouse intestinal epithelial cells

(2011) Yanfang Guan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Programmed Cell Death in Animal Development and Disease

(2011) Yaron Fuchs et al.   CELL

Segment-specific generation of Drosophila Capability neuropeptide neurons by multi-faceted Hox cues

(2011) Anke Suska et al.   DEVELOPMENTAL BIOLOGY

DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity

(2011) Arundhati Sengupta Ghosh et al.   JOURNAL OF CELL BIOLOGY

Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway

(2011) Yapeng Gu et al.   JOURNAL OF CELL BIOLOGY

Deletion of ERK1 and ERK2 in the CNS Causes Cortical Abnormalities and Neonatal Lethality: Erk1 Deficiency Enhances the Impairment of Neurogenesis in Erk2-Deficient Mice

(2011) Y. Satoh et al.   JOURNAL OF NEUROSCIENCE

Poly(ADP-Ribose) (PAR) Binding to Apoptosis-Inducing Factor Is Critical for PAR Polymerase-1-Dependent Cell Death (Parthanatos)

(2011) Y. Wang et al.   Science Signaling

Structure of the Drosophila Apoptosome at 6.9 Å Resolution

(2011) Shujun Yuan et al.   STRUCTURE

Wallerian Degeneration, WldS, and Nmnat

(2010) Michael P. Coleman et al.   Annual Review of Neuroscience

Crystal Structure of the Caenorhabditis elegans Apoptosome Reveals an Octameric Assembly of CED-4

(2010) Shiqian Qi et al.   CELL

Molecular cell death platforms and assemblies

(2010) Peter D Mace et al.   CURRENT OPINION IN CELL BIOLOGY

Axonal Degeneration Is Regulated by the Apoptotic Machinery or a NAD+-Sensitive Pathway in Insects and Mammals

(2010) Z. Schoenmann et al.   JOURNAL OF NEUROSCIENCE

The insect caspases

(2009) Dawn M. Cooper et al.   APOPTOSIS

Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway

(2009) S Inoue et al.   CELL DEATH AND DIFFERENTIATION

Cell-autonomous requirement for DNaseII in nonapoptotic cell death

(2009) B P Bass et al.   CELL DEATH AND DIFFERENTIATION

Caenorhabditis elegans caspase homolog CSP-2 inhibits CED-3 autoactivation and apoptosis in germ cells

(2009) X Geng et al.   CELL DEATH AND DIFFERENTIATION

Autophagy, Not Apoptosis, Is Essential for Midgut Cell Death in Drosophila

(2009) Donna Denton et al.   CURRENT BIOLOGY

Role of Notch signaling in establishing the hemilineages of secondary neurons in Drosophila melanogaster

(2009) J. W. Truman et al.   DEVELOPMENT

Trithorax, Hox, and TALE-class homeodomain proteins ensure cell survival through repression of the BH3-only gene egl-1

(2009) Malia B. Potts et al.   DEVELOPMENTAL BIOLOGY

Parthanatos, a messenger of death

(2009) Karen Kate David   Frontiers in Bioscience-Landmark

Human Caspases: Activation, Specificity, and Regulation

(2009) Cristina Pop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspases: evolutionary aspects of their functions in vertebrates

(2009) K. Sakamaki et al.   JOURNAL OF FISH BIOLOGY

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

Functional Redundancy of TGF-beta Family Type I Receptors and Receptor-Smads in Mediating Anti-Müllerian Hormone-Induced Müllerian Duct Regression in the Mouse1

(2008) G.D. Orvis et al.   BIOLOGY OF REPRODUCTION

Necroptosis: A Specialized Pathway of Programmed Necrosis

(2008) Lorenzo Galluzzi et al.   CELL

Cell death in the host response to infection

(2008) K Labbé et al.   CELL DEATH AND DIFFERENTIATION

Regulation of apoptosis by XIAP ubiquitin-ligase activity

(2008) A. J. Schile et al.   GENES & DEVELOPMENT

FLIP and the death effector domain family

(2008) J W Yu et al.   ONCOGENE

Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex

(2008) L. K. Low et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY