Proteomics reveals a therapeutic vulnerability via the combined blockade of APE1 and autophagy in lung cancer A549 cells
出版年份 2020 全文链接
标题
Proteomics reveals a therapeutic vulnerability via the combined blockade of APE1 and autophagy in lung cancer A549 cells
作者
关键词
-
出版物
BMC CANCER
Volume 20, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-07-08
DOI
10.1186/s12885-020-07111-w
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers
- (2019) Conan G. Kinsey et al. NATURE MEDICINE
- Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
- (2019) Kirsten L. Bryant et al. NATURE MEDICINE
- Oncogenic Ras is downregulated by ARHI and induces autophagy by Ras/AKT/mTOR pathway in glioblastoma
- (2019) Chen Zhong et al. BMC CANCER
- RAS Mutations Are Not Created Equal
- (2019) G. Aaron Hobbs et al. Cancer Discovery
- Current cancer situation in China: good or bad news from the 2018 Global Cancer Statistics?
- (2019) Rui-Mei Feng et al. Cancer Communications
- Cisplatin-resistant triple-negative breast cancer subtypes: multiple mechanisms of resistance
- (2019) David P. Hill et al. BMC CANCER
- Pro-survival autophagy and cancer cell resistance to therapy
- (2018) Chandan Kanta Das et al. CANCER AND METASTASIS REVIEWS
- Novel organometallic chloroquine derivative inhibits tumor growth
- (2018) Elizabeth A. Hall et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Allele-Specific Mechanisms of Activation of MEK1 Mutants Determine Their Properties
- (2018) Yijun Gao et al. Cancer Discovery
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Apurinic/apyrimidinic endonuclease 1 (APE1/Ref-1) overexpression is an independent prognostic marker in prostate cancer without TMPRSS2:ERG fusion
- (2017) Manuela Juhnke et al. MOLECULAR CARCINOGENESIS
- Suppression of p53 potentiates chemosensitivity in nutrient-deprived cholangiocarcinoma cells via inhibition of autophagy
- (2017) Fei Hu et al. Oncology Letters
- Modulating lysosomal function through lysosome membrane permeabilization or autophagy suppression restores sensitivity to cisplatin in refractory non-small-cell lung cancer cells
- (2017) Magdalena Circu et al. PLoS One
- rs1760944 Polymorphism in the APE1 Region is Associated with Risk and Prognosis of Osteosarcoma in the Chinese Han Population
- (2017) Xing Xiao et al. Scientific Reports
- APE1 overexpression promotes the progression of ovarian cancer and serves as a potential therapeutic target
- (2016) Xuemei Wen et al. Cancer Biomarkers
- Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells
- (2016) Si-Jia He et al. CANCER LETTERS
- ER stress and autophagy are involved in the apoptosis induced by cisplatin in human lung cancer cells
- (2016) SHAOMIN SHI et al. ONCOLOGY REPORTS
- ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells
- (2015) Jing-Hong Chen et al. Autophagy
- The utility of chloroquine in cancer therapy
- (2015) Yuan Zhang et al. CURRENT MEDICAL RESEARCH AND OPINION
- Genistein induces apoptosis by stabilizing intracellular p53 protein through an APE1-mediated pathway
- (2015) Jianwu Zhu et al. FREE RADICAL BIOLOGY AND MEDICINE
- The role for autophagy in cancer
- (2015) Eileen White JOURNAL OF CLINICAL INVESTIGATION
- Inhibition of autophagy enhances cisplatin-induced apoptosis in the MG63 human osteosarcoma cell line
- (2015) ZHICAI ZHANG et al. Oncology Letters
- Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance
- (2015) Jesús García-Cano et al. Oncotarget
- Cisplatin in cancer therapy: Molecular mechanisms of action
- (2014) Shaloam Dasari et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Association of DNA base excision repair genes (OGG1,APE1andXRCC1) polymorphisms with outcome to platinum-based chemotherapy in advanced nonsmall-cell lung cancer patients
- (2014) Yu Peng et al. INTERNATIONAL JOURNAL OF CANCER
- Role of Autophagy in Cisplatin Resistance in Ovarian Cancer Cells
- (2014) Juan Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy Inhibition Improves Chemosensitivity in BRAFV600E Brain Tumors
- (2014) J. M. M. Levy et al. Cancer Discovery
- Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
- (2014) G. Karsli-Uzunbas et al. Cancer Discovery
- Sequential treatment with AT-101 enhances cisplatin chemosensitivity in human non-small cell lung cancer cells through inhibition of apurinic/apyrimidinic endonuclease 1-activated IL-6/STAT3 signaling pathway
- (2014) Tao Ren et al. Drug Design Development and Therapy
- Human Apurinic/Apyrimidinic Endonuclease 1
- (2013) Mengxia Li et al. ANTIOXIDANTS & REDOX SIGNALING
- Genetics and biomarkers in personalisation of lung cancer treatment
- (2013) Rafael Rosell et al. LANCET
- Proteomics-based identification of secreted protein dihydrodiol dehydrogenase 2 as a potential biomarker for predicting cisplatin efficacy in advanced NSCLC patients
- (2012) Peng Kuang et al. LUNG CANCER
- Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
- (2011) J. Y. Guo et al. GENES & DEVELOPMENT
- Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
- (2010) Rebecca Lock et al. MOLECULAR BIOLOGY OF THE CELL
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