Absence of MHC class II on cDC1 dendritic cells triggers fatal autoimmunity to a cross-presented self-antigen

Unregulated antigen-presenting cell activation by T cells breaks self tolerance

(2019) Jaeu Yi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control

(2018) Jan P. Böttcher et al.   CELL

Conditional Gene-Targeting in Mice: Problems and Solutions

(2018) Burkhard Becher et al.   IMMUNITY

Suppression of Tcf1 by Inflammatory Cytokines Facilitates Effector CD8 T Cell Differentiation

(2018) Maxime Danilo et al.   Cell Reports

CD8 + T Cells Orchestrate pDC-XCR1 + Dendritic Cell Spatial and Functional Cooperativity to Optimize Priming

(2017) Anna Brewitz et al.   IMMUNITY

CD4 + T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness

(2017) Tomasz Ahrends et al.   IMMUNITY

Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation

(2017) Bryan Vander Lugt et al.   JOURNAL OF CELL BIOLOGY

Suppression of lethal autoimmunity by regulatory T cells with a single TCR specificity

(2017) Andrew G. Levine et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Slamf6 negatively regulates autoimmunity

(2016) Ninghai Wang et al.   CLINICAL IMMUNOLOGY

Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery

(2016) Laurence Ardouin et al.   IMMUNITY

Functions of Murine Dendritic Cells

(2016) Vivek Durai et al.   IMMUNITY

Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species

(2016) Martin Guilliams et al.   IMMUNITY

Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells

(2016) Daniel S. Leventhal et al.   IMMUNITY

Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation

(2016) Jakob Loschko et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis

(2016) Tomokazu Ohta et al.   Scientific Reports

CD4 + T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion

(2015) Francois P. Legoux et al.   IMMUNITY

Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes

(2015) Wong Yu et al.   IMMUNITY

Regulatory dendritic cells in autoimmunity: A comprehensive review

(2015) Juan Liu et al.   JOURNAL OF AUTOIMMUNITY

Selective Treg reconstitution during lymphopenia normalizes DC costimulation and prevents graft-versus-host disease

(2015) Holly A. Bolton et al.   JOURNAL OF CLINICAL INVESTIGATION

XCR1+dendritic cells promote memory CD8+T cell recall upon secondary infections withListeria monocytogenesor certain viruses

(2015) Yannick O. Alexandre et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Homeostasis and Effector Function of Lymphopenia-Induced "Memory-Like" T Cells in Constitutively T Cell-Depleted Mice

(2014) D. Voehringer et al.   JOURNAL OF IMMUNOLOGY

The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function

(2014) Kristin A Hogquist et al.   NATURE IMMUNOLOGY

Detection of self-reactive CD8+T cells with an anergic phenotype in healthy individuals

(2014) Yuka Maeda et al.   SCIENCE

Release of dendritic cells from cognate CD4+ T-cell recognition results in impaired peripheral tolerance and fatal cytotoxic T-cell mediated autoimmunity

(2012) S. Muth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of XCR1 Characterizes the Batf3-Dependent Lineage of Dendritic Cells Capable of Antigen Cross-Presentation

(2012) Annabell Bachem et al.   Frontiers in Immunology

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+dendritic cells

(2010) Karine Crozat et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A critical role for regulatory T cell–mediated control of inflammation in the absence of commensal microbiota

(2010) Takatoshi Chinen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen-Specific CD4 Cells Assist CD8 T-Effector Cells in Eliminating Keratinocytes

(2010) Jennifer K. Broom et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dendritic cells control T cell tonic signaling required for responsiveness to foreign antigen

(2010) K. Hochweller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CX3CR1+ CD8 + dendritic cells are a steady-state population related to plasmacytoid dendritic cells

(2010) L. Bar-On et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Expression of the Chemokine Receptor XCR1 on Cross-presenting Dendritic Cells Determines Cooperation with CD8+ T Cells

(2009) Brigitte G. Dorner et al.   IMMUNITY

CD207+CD103+dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

(2009) Sandrine Henri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

Agouti C57BL/6N embryonic stem cells for mouse genetic resources

(2009) Stephen J Pettitt et al.   NATURE METHODS