Shedding New Light on Cancer Metabolism: A Metabolic Tightrope Between Life and Death
出版年份 2020 全文链接
标题
Shedding New Light on Cancer Metabolism: A Metabolic Tightrope Between Life and Death
作者
关键词
-
出版物
Frontiers in Oncology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-03-31
DOI
10.3389/fonc.2020.00409
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mechanical regulation of glycolysis via cytoskeleton architecture
- (2020) Jin Suk Park et al. NATURE
- Genome-wide analysis reveals miR-3184-5p and miR-181c-3p as a critical regulator for adipocytes-associated breast cancer
- (2019) Dheeran Rajarajan et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The loss of succinate dehydrogenase B expression is frequently identified in hemangioblastoma of the central nervous system
- (2019) Tae Hoon Roh et al. Scientific Reports
- Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer
- (2019) Neha M. Akella et al. BMC BIOLOGY
- UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis
- (2019) Xiongjun Wang et al. NATURE
- Metabolic signal curbs cancer-cell migration
- (2019) Lydia W. S. Finley NATURE
- UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression
- (2019) James M. Arnold et al. ONCOGENE
- Elevated level of mitochondrial reactive oxygen species via fatty acid β-oxidation in cancer stem cells promotes cancer metastasis by inducing epithelial–mesenchymal transition
- (2019) Caihua Wang et al. Stem Cell Research & Therapy
- Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis
- (2019) Brian E. Hsu et al. Cell Reports
- In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer
- (2019) Milica Momcilovic et al. NATURE
- Metabolic regulation of gene expression by histone lactylation
- (2019) Di Zhang et al. NATURE
- Convergence of Cancer Metabolism and Immunity: an Overview
- (2018) Chi Van Dang et al. Biomolecules & Therapeutics
- Unique Metabolic Adaptations Dictate Distal Organ-Specific Metastatic Colonization
- (2018) Tanya Schild et al. CANCER CELL
- Transketolase Regulates the Metabolic Switch to Control Breast Cancer Cell Metastasis via the α-Ketoglutarate Signaling Pathway
- (2018) Chien-Wei Tseng et al. CANCER RESEARCH
- Interplay between ShcA signaling and PGC-1α triggers targetable metabolic vulnerabilities in breast cancer
- (2018) Young Kyuen Im et al. CANCER RESEARCH
- Extracellular Citrate Affects Critical Elements of Cancer Cell Metabolism and Supports Cancer DevelopmentIn Vivo
- (2018) Maria E. Mycielska et al. CANCER RESEARCH
- Normoxic cells remotely regulate the acid-base balance of cells at the hypoxic core of connexin-coupled tumor growths
- (2018) Tobias H. Dovmark et al. FASEB JOURNAL
- Isocitrate dehydrogenase 1–mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress
- (2018) Krissie Lenting et al. FASEB JOURNAL
- Protein kinase CK2 modulation of pyruvate kinase M isoforms augments the Warburg effect in cancer cells
- (2018) Kyung Mi Yang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer
- (2018) Steven C. Eastlack et al. Molecular Cancer
- Leptin Signaling Mediates Obesity-Associated CSC Enrichment and EMT in Preclinical TNBC Models
- (2018) Laura W. Bowers et al. MOLECULAR CANCER RESEARCH
- Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance
- (2018) Jacqueline R. Ha et al. MOLECULAR CANCER RESEARCH
- NADH Shuttling Couples Cytosolic Reductive Carboxylation of Glutamine with Glycolysis in Cells with Mitochondrial Dysfunction
- (2018) Edoardo Gaude et al. MOLECULAR CELL
- Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth
- (2018) Ilenia Pacella et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Secreted molecules inducing epithelial-to-mesenchymal transition in cancer development
- (2018) Elisa Dalla Pozza et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Oxygen-Sensitive Remodeling of Central Carbon Metabolism by Archaic eIF5B
- (2018) J.J. David Ho et al. Cell Reports
- Increased Lactate in Gastric Cancer Tumor-Infiltrating Lymphocytes Is Related to Impaired T Cell Function Due to miR-34a Deregulated Lactate Dehydrogenase A
- (2018) Wang Ping et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- miR-143 Regulates Memory T Cell Differentiation by Reprogramming T Cell Metabolism
- (2018) Tengfei Zhang et al. JOURNAL OF IMMUNOLOGY
- Identification of the tumour transition states occurring during EMT
- (2018) Ievgenia Pastushenko et al. NATURE
- LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response
- (2018) Inna Serganova et al. PLoS One
- Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition
- (2017) Andrew P. Trotta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fermentative metabolism impedes p53-dependent apoptosis in a Crabtree-positive but not in Crabtree-negative yeast
- (2017) Abhay Kumar et al. JOURNAL OF BIOSCIENCES
- ADAM12 induction by Twist1 promotes tumor invasion and metastasis via regulation of invadopodia and focal adhesions
- (2017) Mark A. Eckert et al. JOURNAL OF CELL SCIENCE
- Metabolic shifts in residual breast cancer drive tumor recurrence
- (2017) Kristina M. Havas et al. JOURNAL OF CLINICAL INVESTIGATION
- Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
- (2017) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
- Mitochondrial elongation-mediated glucose metabolism reprogramming is essential for tumour cell survival during energy stress
- (2017) J Li et al. ONCOGENE
- Cancer stem cells: The root of tumor recurrence and metastases
- (2017) Claudia Peitzsch et al. SEMINARS IN CANCER BIOLOGY
- Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming
- (2017) Shujuan Sun et al. Cell Death & Disease
- Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancer
- (2017) Yang-An Wen et al. Cell Death & Disease
- Mitochondrial metabolites: undercover signalling molecules
- (2017) Christian Frezza Interface Focus
- Cell surface GRP78 promotes tumor cell histone acetylation through metabolic reprogramming: a mechanism which modulates the Warburg effect
- (2017) Udhayakumar Gopal et al. Oncotarget
- Lactate-activated macrophages induced aerobic glycolysis and epithelial-mesenchymal transition in breast cancer by regulation of CCL5-CCR5 axis: a positive metabolic feedback loop
- (2017) Sensen Lin et al. Oncotarget
- Angiogenesis revisited from a metabolic perspective: role and therapeutic implications of endothelial cell metabolism
- (2017) Nihed Draoui et al. Open Biology
- The Crabtree and Warburg effects: Do metabolite-induced regulations participate in their induction?
- (2016) Noureddine Hammad et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The mitochondrial pyruvate carrier in health and disease: To carry or not to carry?
- (2016) Tom Bender et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- IRAK-M Expression in Tumor Cells Supports Colorectal Cancer Progression through Reduction of Antimicrobial Defense and Stabilization of STAT3
- (2016) Rebecca Kesselring et al. CANCER CELL
- Hyaluronan: A modulator of the tumor microenvironment
- (2016) Theerawut Chanmee et al. CANCER LETTERS
- Metabolic Plasticity as a Determinant of Tumor Growth and Metastasis
- (2016) Camille Lehuédé et al. CANCER RESEARCH
- EMT: 2016
- (2016) M. Angela Nieto et al. CELL
- Metabolic Heterogeneity in Human Lung Tumors
- (2016) Christopher T. Hensley et al. CELL
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells
- (2016) Jonathan L. Coloff et al. Cell Metabolism
- Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis
- (2016) Mathias Wenes et al. Cell Metabolism
- Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer
- (2016) Shawn M. Davidson et al. Cell Metabolism
- Hypoglycemia Enhances Epithelial-Mesenchymal Transition and Invasiveness, and Restrains the Warburg Phenotype, in Hypoxic HeLa Cell Cultures and Microspheroids
- (2016) Álvaro Marín-Hernández et al. JOURNAL OF CELLULAR PHYSIOLOGY
- U2AF35(S34F) Promotes Transformation by Directing Aberrant ATG7 Pre-mRNA 3′ End Formation
- (2016) Sung Mi Park et al. MOLECULAR CELL
- Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells
- (2016) Oliver D.K. Maddocks et al. MOLECULAR CELL
- Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
- (2016) Marco Sciacovelli et al. NATURE
- Reductive carboxylation supports redox homeostasis during anchorage-independent growth
- (2016) Lei Jiang et al. NATURE
- Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
- (2016) Cristovão M. Sousa et al. NATURE
- Metastatic colonization by circulating tumour cells
- (2016) Joan Massagué et al. NATURE
- Ischaemic conditioning and reperfusion injury
- (2016) Derek J. Hausenloy et al. Nature Reviews Cardiology
- Cancer metabolism: a therapeutic perspective
- (2016) Ubaldo E. Martinez-Outschoorn et al. Nature Reviews Clinical Oncology
- Regulated necrosis: disease relevance and therapeutic opportunities
- (2016) Marcus Conrad et al. NATURE REVIEWS DRUG DISCOVERY
- Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers
- (2016) J. R. Mayers et al. SCIENCE
- Mitochondrial Permeability Transition: New Findings and Persisting Uncertainties
- (2016) Valentina Izzo et al. TRENDS IN CELL BIOLOGY
- Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity
- (2016) Victor Laurent et al. Nature Communications
- A neuronal network of mitochondrial dynamics regulates metastasis
- (2016) M. Cecilia Caino et al. Nature Communications
- Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse
- (2016) Marco Demaria et al. Cancer Discovery
- Resistance to Antiangiogenic Therapies by Metabolic Symbiosis in Renal Cell Carcinoma PDX Models and Patients
- (2016) Gabriela Jiménez-Valerio et al. Cell Reports
- Metabolic Symbiosis Enables Adaptive Resistance to Anti-angiogenic Therapy that Is Dependent on mTOR Signaling
- (2016) Elizabeth Allen et al. Cell Reports
- Targeting Metabolic Symbiosis to Overcome Resistance to Anti-angiogenic Therapy
- (2016) Laura Pisarsky et al. Cell Reports
- Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer
- (2016) Jun Hyoung Park et al. Cell Reports
- Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions
- (2016) Geou-Yarh Liou et al. Cell Reports
- A nonrandomized cohort and a randomized study of local control of large hepatocarcinoma by targeting intratumoral lactic acidosis
- (2016) Ming Chao et al. eLife
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
- Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
- (2015) Chih-Hao Chang et al. CELL
- MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells
- (2015) Patricia Sancho et al. Cell Metabolism
- PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer
- (2015) Fanny Dupuy et al. Cell Metabolism
- Acetyl Coenzyme A: A Central Metabolite and Second Messenger
- (2015) Federico Pietrocola et al. Cell Metabolism
- Redox Homeostasis and Mitochondrial Dynamics
- (2015) Peter H.G.M. Willems et al. Cell Metabolism
- SIRT1/PGC1 -Dependent Increase in Oxidative Phosphorylation Supports Chemotherapy Resistance of Colon Cancer
- (2015) T. T. Vellinga et al. CLINICAL CANCER RESEARCH
- Autophagy in malignant transformation and cancer progression
- (2015) L. Galluzzi et al. EMBO JOURNAL
- Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis
- (2015) A. H. Chourasia et al. EMBO REPORTS
- Reshaping of Human Macrophage Polarization through Modulation of Glucose Catabolic Pathways
- (2015) Elena Izquierdo et al. JOURNAL OF IMMUNOLOGY
- Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy
- (2015) Jagadish C. Ghosh et al. JNCI-Journal of the National Cancer Institute
- Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling
- (2015) Hee-Bum Kang et al. MOLECULAR CELL
- Oxidative stress inhibits distant metastasis by human melanoma cells
- (2015) Elena Piskounova et al. NATURE
- PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
- (2015) M. Cecilia Caino et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion
- (2015) Dayana B. Rivadeneira et al. Science Signaling
- Antioxidants can increase melanoma metastasis in mice
- (2015) Kristell Le Gal et al. Science Translational Medicine
- Hypoxic Microenvironment Induces EMT and Upgrades Stem-Like Properties of Gastric Cancer Cells
- (2015) Jinbao Guo et al. TECHNOLOGY IN CANCER RESEARCH & TREATMENT
- Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death
- (2015) Daniela Catanzaro et al. Oncotarget
- GLUT3 and PKM2 regulate OCT4 expression and support the hypoxic culture of human embryonic stem cells
- (2015) David R. Christensen et al. Scientific Reports
- Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy
- (2015) Jagadish C. Ghosh et al. JNCI-Journal of the National Cancer Institute
- Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion
- (2015) Dayana B. Rivadeneira et al. Science Signaling
- MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells
- (2015) Elena Catalán et al. OncoImmunology
- Epithelial-to-Mesenchymal Transition and Cancer Invasiveness: What Can We Learn from Cholangiocarcinoma?
- (2015) Simone Brivio et al. Journal of Clinical Medicine
- Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells
- (2015) Keita Shibuya et al. Oncotarget
- Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation
- (2015) Anna Pastò et al. Oncotarget
- A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer
- (2014) Nelma Pértega-Gomes et al. BMC CANCER
- Krüppel-like factor 8 contributes to hypoxia-induced MDR in gastric cancer cells
- (2014) Hui Zhang et al. CANCER SCIENCE
- Metabolic Control of Autophagy
- (2014) Lorenzo Galluzzi et al. CELL
- Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases
- (2014) Tomoyuki Mashimo et al. CELL
- Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization
- (2014) Zixue Jin et al. Cell Metabolism
- Hypoxic Regulation of Glutamine Metabolism through HIF1 and SIAH2 Supports Lipid Synthesis that Is Necessary for Tumor Growth
- (2014) Ramon C. Sun et al. Cell Metabolism
- Phosphofructokinase: A mediator of glycolytic flux in cancer progression
- (2014) Nada Al Hasawi et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- The unfolded protein response potentiates epithelial-to-mesenchymal transition (EMT) of gastric cancer cells under severe hypoxic conditions
- (2014) Xinsheng Shen et al. MEDICAL ONCOLOGY
- Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A
- (2014) Guillermo Mariño et al. MOLECULAR CELL
- A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration
- (2014) K. Yizhak et al. Molecular Systems Biology
- Quantitative flux analysis reveals folate-dependent NADPH production
- (2014) Jing Fan et al. NATURE
- Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
- (2014) Andrea Viale et al. NATURE
- Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
- (2014) Supriya K. Saha et al. NATURE
- PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
- (2014) Valerie S. LeBleu et al. NATURE CELL BIOLOGY
- Unraveling the Truth About Antioxidants: Mitohormesis explains ROS-induced health benefits
- (2014) Michael Ristow NATURE MEDICINE
- Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition
- (2014) M Bonora et al. ONCOGENE
- Antioxidants Accelerate Lung Cancer Progression in Mice
- (2014) V. I. Sayin et al. Science Translational Medicine
- Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment
- (2014) D Ciavardelli et al. Cell Death & Disease
- Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia
- (2014) J. Ye et al. Cancer Discovery
- Beyond Warburg effect – dual metabolic nature of cancer cells
- (2014) Jiansheng Xie et al. Scientific Reports
- A Mitochondrial Switch Promotes Tumor Metastasis
- (2014) Paolo E. Porporato et al. Cell Reports
- Role of PFKFB3-Driven Glycolysis in Vessel Sprouting
- (2013) Katrien De Bock et al. CELL
- Energy Metabolism Characterization of a Novel Cancer Stem Cell-Like Line 3AB-OS
- (2013) Roberta Palorini et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
- (2013) Cosimo Commisso et al. NATURE
- p53 status determines the role of autophagy in pancreatic tumour development
- (2013) Mathias T. Rosenfeldt et al. NATURE
- Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
- (2013) Jaekyoung Son et al. NATURE
- Synthetic lethal metabolic targeting of cellular senescence in cancer therapy
- (2013) Jan R. Dörr et al. NATURE
- Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
- (2013) Peter E. Czabotar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Hypoxia Stimulates the EMT of Gastric Cancer Cells through Autocrine TGFβ Signaling
- (2013) Junko Matsuoka et al. PLoS One
- Sub-Sets of Cancer Stem Cells Differ Intrinsically in Their Patterns of Oxygen Metabolism
- (2013) Luke Gammon et al. PLoS One
- Tumor Environmental Factors Glucose Deprivation and Lactic Acidosis Induce Mitotic Chromosomal Instability – An Implication in Aneuploid Human Tumors
- (2013) Chunyan Dai et al. PLoS One
- Catabolism of Exogenous Lactate Reveals It as a Legitimate Metabolic Substrate in Breast Cancer
- (2013) Kelly M. Kennedy et al. PLoS One
- Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3
- (2013) P. Mao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- (R)-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
- (2013) J.-A. Losman et al. SCIENCE
- Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells
- (2013) Sarah-Maria Fendt et al. Nature Communications
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
- (2012) T. Fiaschi et al. CANCER RESEARCH
- The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type
- (2012) Mariia O. Yuneva et al. Cell Metabolism
- The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism
- (2012) Arvand Haschemi et al. Cell Metabolism
- Inhibition of -KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors
- (2012) M. Xiao et al. GENES & DEVELOPMENT
- Metabolic symbiosis in cancer: Refocusing the Warburg lens
- (2012) Erica C. Nakajima et al. MOLECULAR CARCINOGENESIS
- The Mitochondrial ATPase Inhibitory Factor 1 Triggers a ROS-Mediated Retrograde Prosurvival and Proliferative Response
- (2012) Laura Formentini et al. MOLECULAR CELL
- Physiological Roles of Mitochondrial Reactive Oxygen Species
- (2012) Laura A. Sena et al. MOLECULAR CELL
- IDH mutation impairs histone demethylation and results in a block to cell differentiation
- (2012) Chao Lu et al. NATURE
- Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
- (2012) Peppi Koivunen et al. NATURE
- Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
- (2012) Rhonda M. Perciavalle et al. NATURE CELL BIOLOGY
- Oxygen delivery and fetal-placental growth: Beyond a question of supply and demand?
- (2012) A.J. Murray PLACENTA
- Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
- (2012) M. Jain et al. SCIENCE
- Transcriptional up-regulation of RhoE by hypoxia-inducible factor (HIF)-1 promotes epithelial to mesenchymal transition of gastric cancer cells during hypoxia
- (2011) Jinfeng Zhou et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Succination of Keap1 and Activation of Nrf2-Dependent Antioxidant Pathways in FH-Deficient Papillary Renal Cell Carcinoma Type 2
- (2011) Lisa Kinch et al. CANCER CELL
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect
- (2011) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca2+ buffering
- (2011) J Traba et al. CELL DEATH AND DIFFERENTIATION
- HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells
- (2011) Giuseppina Comito et al. FREE RADICAL BIOLOGY AND MEDICINE
- Central role of lactic acidosis in cancer cell resistance to glucose deprivation-induced cell death
- (2011) Hao Wu et al. JOURNAL OF PATHOLOGY
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
- (2011) Gina M. DeNicola et al. NATURE
- Reductive carboxylation supports growth in tumour cells with defective mitochondria
- (2011) Andrew R. Mullen et al. NATURE
- Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
- (2011) Christian M. Metallo et al. NATURE
- Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase
- (2011) Kambiz N. Alavian et al. NATURE CELL BIOLOGY
- During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
- (2011) Ligia C. Gomes et al. NATURE CELL BIOLOGY
- Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
- (2011) Kristin M Nieman et al. NATURE MEDICINE
- Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism
- (2010) Anne S. Tibbetts et al. Annual Review of Nutrition
- Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells
- (2010) A Caro-Maldonado et al. CELL DEATH AND DIFFERENTIATION
- Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
- (2010) F. Weinberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Placental metabolic reprogramming: do changes in the mix of energy-generating substrates modulate fetal growth?
- (2009) Nicholas P. Illsley et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- The Warburg Effect Suppresses Oxidative Stress Induced Apoptosis in a Yeast Model for Cancer
- (2009) Christoph Ruckenstuhl et al. PLoS One
- Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells
- (2009) Olivier Feron RADIOTHERAPY AND ONCOLOGY
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
- (2009) K. E. Wellen et al. SCIENCE
- ShcA signalling is essential for tumour progression in mouse models of human breast cancer
- (2008) Josie Ursini-Siegel et al. EMBO JOURNAL
- Mitochondrial Oxidative Phosphorylation Is Regulated by Fructose 1,6-Bisphosphate
- (2008) Rodrigo Díaz-Ruiz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
- (2008) Pierre Sonveaux et al. JOURNAL OF CLINICAL INVESTIGATION
- Signaling through ShcA Is Required for Transforming Growth Factor - and Neu/ErbB-2-Induced Breast Cancer Cell Motility and Invasion
- (2008) J. J. Northey et al. MOLECULAR AND CELLULAR BIOLOGY
- Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
- (2008) Allyson E. Vaughn et al. NATURE CELL BIOLOGY
- ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis
- (2008) K. Ishikawa et al. SCIENCE
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