标题
Phosphodiesterase 4B: Master Regulator of Brain Signaling
作者
关键词
-
出版物
Cells
Volume 9, Issue 5, Pages 1254
出版商
MDPI AG
发表日期
2020-05-20
DOI
10.3390/cells9051254
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Peptide-mediated drug delivery across the blood-brain barrier for targeting brain tumors
- (2019) Behzad Jafari et al. Expert Opinion on Drug Delivery
- Understanding PDE4's function in Alzheimer's disease; a target for novel therapeutic approaches
- (2019) Amy J. Tibbo et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide
- (2019) Lin-Ping Wu et al. Nature Communications
- Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases
- (2018) Heng Li et al. Frontiers in Pharmacology
- Phosphodiesterase 4b expression plays a major role in alcohol-induced neuro-inflammation
- (2017) Diana V. Avila et al. NEUROPHARMACOLOGY
- Therapeutic benefits of phosphodiesterase 4B inhibition after traumatic brain injury
- (2017) Nicole M. Wilson et al. PLoS One
- Blood–brain barrier shuttle peptides: an emerging paradigm for brain delivery
- (2016) Benjamí Oller-Salvia et al. CHEMICAL SOCIETY REVIEWS
- Association of PDE4B Polymorphisms with Susceptibility to Schizophrenia: A Meta-Analysis of Case-Control Studies
- (2016) Yanguo Feng et al. PLoS One
- The cAMP Pathway as Therapeutic Target in Autoimmune and Inflammatory Diseases
- (2016) Verena Katharina Raker et al. Frontiers in Immunology
- Ten-Year Employment Patterns of Working Age Individuals After Moderate to Severe Traumatic Brain Injury: A National Institute on Disability and Rehabilitation Research Traumatic Brain Injury Model Systems Study
- (2015) Jeffrey P. Cuthbert et al. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
- Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition
- (2015) Alexander McGirr et al. NEUROPSYCHOPHARMACOLOGY
- Engineered stabilization and structural analysis of the autoinhibited conformation of PDE4
- (2015) Peder Cedervall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Interplay between Cyclic AMP, MAPK, and NF-κB Pathways in Response to Proinflammatory Signals in Microglia
- (2015) Mousumi Ghosh et al. Biomed Research International
- The upstream conserved regions (UCRs) mediate homo- and hetero-oligomerization of type 4 cyclic nucleotide phosphodiesterases (PDE4s)
- (2014) Moses Xie et al. BIOCHEMICAL JOURNAL
- Inhibition of phosphodiesterase 4 reduces ethanol intake and preference in C57BL/6J mice
- (2014) Yuri A. Blednov et al. Frontiers in Neuroscience
- Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors
- (2013) Taiji Goto et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Combining Neurotrophin-Transduced Schwann Cells and Rolipram to Promote Functional Recovery from Subacute Spinal Cord Injury
- (2013) Govinder Flora et al. CELL TRANSPLANTATION
- Select 3′,5′-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain
- (2013) Michy P. Kelly et al. CELLULAR SIGNALLING
- Structural basis for the design of selective phosphodiesterase 4B inhibitors
- (2013) David Fox et al. CELLULAR SIGNALLING
- PDE4 as a target for cognition enhancement
- (2013) Wito Richter et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Heavy Ethanol Intoxication Increases Proinflammatory Cytokines and Aggravates Hemorrhagic Shock-Induced Organ Damage in Rats
- (2013) Tsung-Ming Hu et al. MEDIATORS OF INFLAMMATION
- PDE Inhibition and cognition enhancement
- (2012) Arjan Blokland et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Proinflammatory cytokine regulation of cyclic AMP-phosphodiesterase 4 signaling in microgliain vitroand following CNS injury
- (2012) Mousumi Ghosh et al. GLIA
- A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins
- (2012) Jennifer E. Eykelenboom et al. HUMAN MOLECULAR GENETICS
- Phosphodiesterase isoform-specific expression induced by traumatic brain injury
- (2012) Anthony A. Oliva et al. JOURNAL OF NEUROCHEMISTRY
- Cognitive decline in older adults with a history of traumatic brain injury
- (2012) Laura Moretti et al. LANCET NEUROLOGY
- Age-dependent alterations in cAMP signaling contribute to synaptic plasticity deficits following traumatic brain injury
- (2012) D.J. Titus et al. NEUROSCIENCE
- Comparison of cAMP-specific phosphodiesterase mRNAs distribution in mouse and rat brain
- (2012) Emily M. Johansson et al. NEUROSCIENCE LETTERS
- Effects of early rolipram treatment on histopathological outcome after controlled cortical impact injury in mice
- (2012) Coleen M. Atkins et al. NEUROSCIENCE LETTERS
- PKA Phosphorylation of NDE1 Is DISC1/PDE4 Dependent and Modulates Its Interaction with LIS1 and NDEL1
- (2011) N. J. Bradshaw et al. JOURNAL OF NEUROSCIENCE
- Enhanced long-term depression and impaired reversal learning in phosphodiesterase 4B-knockout (PDE4B−/−) mice
- (2011) Kris Rutten et al. NEUROPHARMACOLOGY
- Mammalian Cyclic Nucleotide Phosphodiesterases: Molecular Mechanisms and Physiological Functions
- (2011) Sharron H. Francis et al. PHYSIOLOGICAL REVIEWS
- Inhibition of phosphodiesterase-4 decreases ethanol intake in mice
- (2011) Wei Hu et al. PSYCHOPHARMACOLOGY
- cAMP: Novel concepts in compartmentalised signalling
- (2011) Helen V. Edwards et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- CREB: a multifaceted regulator of neuronal plasticity and protection
- (2010) Kensuke Sakamoto et al. JOURNAL OF NEUROCHEMISTRY
- The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- (2010) Taro Kawai et al. NATURE IMMUNOLOGY
- cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
- (2010) S. H. Francis et al. PHARMACOLOGICAL REVIEWS
- The Role of Type 4 Phosphodiesterases in Generating Microdomains of cAMP: Large Scale Stochastic Simulations
- (2010) Rodrigo F. Oliveira et al. PLoS One
- Cyclic AMP-specific PDEs: A promising therapeutic target for CNS repair
- (2010) Mousumi Ghosh et al. Translational Neuroscience
- Seizures, enhanced excitation, and increased vesicle number inLis1mutant mice
- (2009) Joel S.F. Greenwood et al. ANNALS OF NEUROLOGY
- Discovery of selective PDE4B inhibitors
- (2009) Kenji Naganuma et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases
- (2009) George S. Baillie FEBS Journal
- Critical Role of TLR4 Response in the Activation of Microglia Induced by Ethanol
- (2009) S. Fernandez-Lizarbe et al. JOURNAL OF IMMUNOLOGY
- Phosphodiesterase 4B2 gene is an effector of Toll-like receptor signaling in astrocytes
- (2009) Elizabeth Borysiewicz et al. METABOLIC BRAIN DISEASE
- An essential role of the aPKC–Aurora A–NDEL1 pathway in neurite elongation by modulation of microtubule dynamics
- (2009) Daisuke Mori et al. NATURE CELL BIOLOGY
- NCS-1 in the Dentate Gyrus Promotes Exploration, Synaptic Plasticity, and Rapid Acquisition of Spatial Memory
- (2009) Bechara J. Saab et al. NEURON
- Transcription Factors in Long-Term Memory and Synaptic Plasticity
- (2009) Cristina M. Alberini PHYSIOLOGICAL REVIEWS
- Regulation of amygdalar PKA by -arrestin-2/phosphodiesterase-4 complex is critical for fear conditioning
- (2009) Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease
- (2008) Leila Gobejishvili et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- DISC1, PDE4B, and NDE1 at the centrosome and synapse
- (2008) Nicholas J. Bradshaw et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nudel Binds Cdc42GAP to Modulate Cdc42 Activity at the Leading Edge of Migrating Cells
- (2008) Yidong Shen et al. DEVELOPMENTAL CELL
- Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells
- (2008) Sachin Hebbar et al. JOURNAL OF CELL BIOLOGY
- Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment
- (2008) Liya Qin et al. Journal of Neuroinflammation
- Up-regulation of exploratory tendencies does not enhance general learning abilities in juvenile or young-adult outbred mice
- (2008) Kenneth R. Light et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia
- (2008) S. Hossein Fatemi et al. SCHIZOPHRENIA RESEARCH
- Increased MCP-1 and microglia in various regions of the human alcoholic brain
- (2007) Jun He et al. EXPERIMENTAL NEUROLOGY
- Behavioral characterization of mice deficient in the phosphodiesterase-10A (PDE10A) enzyme on a C57/Bl6N congenic background
- (2007) Judith A. Siuciak et al. NEUROPHARMACOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started