Cell death induced by cytotoxic CD8+T cells is immunogenic and primes caspase-3–dependent spread immunity against endogenous tumor antigens

Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen

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Antigen-specific primed cytotoxic T cells eliminate tumour cells in vivo and prevent tumour development, regardless of the presence of anti-apoptotic mutations conferring drug resistance

(2018) Paula Jaime-Sánchez et al.   CELL DEATH AND DIFFERENTIATION

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Unmasking Pancreatic Cancer: Epitope Spreading After Single Antigen Chimeric Antigen Receptor T-Cell Therapy in a Human Phase I Trial

(2018) Max Heckler et al.   GASTROENTEROLOGY

Programmed Cell Death in Immune Defense: Knowledge and Presumptions

(2018) David Wallach et al.   IMMUNITY

The Immune System in Oncolytic Immunovirotherapy: Gospel, Schism and Heresy

(2018) Richard G. Vile   MOLECULAR THERAPY

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(2018) Antoni Ribas et al.   SCIENCE

Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance

(2017) Norma Bloy et al.   IMMUNOLOGICAL REVIEWS

Human Tumor Antigens Yesterday, Today, and Tomorrow

(2017) Olivera J. Finn   Cancer Immunology Research

How Do Cytotoxic Lymphocytes Kill Cancer Cells?

(2015) L. Martinez-Lostao et al.   CLINICAL CANCER RESEARCH

Mouse Cytotoxic T Cell-derived Granzyme B Activates the Mitochondrial Cell Death Pathway in a Bim-dependent Fashion

(2015) Elena Catalán et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer Immunotherapy with Immunomodulatory Anti-CD137 and Anti-PD-1 Monoclonal Antibodies Requires BATF3-Dependent Dendritic Cells

(2015) A. R. Sanchez-Paulete et al.   Cancer Discovery

Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

(2015) Abhishek D. Garg et al.   Frontiers in Immunology

Batf3-dependent CD103+dendritic cells are major producers of IL-12 that drive local Th1 immunity againstLeishmania majorinfection in mice

(2014) María Martínez-López et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments

(2013) H Inoue et al.   CELL DEATH AND DIFFERENTIATION

Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells

(2013) Yuting Ma et al.   IMMUNITY

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Natural Innate and Adaptive Immunity to Cancer

(2011) Matthew D. Vesely et al.   Annual Review of Immunology

A Critical Role for Granzymes in Antigen Cross-Presentation through Regulating Phagocytosis of Killed Tumor Cells

(2011) S. Hoves et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death

(2009) Theocharis Panaretakis et al.   EMBO JOURNAL

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity

(2008) Jennifer D. Stone et al.   IMMUNOLOGY

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE