Natural Innate and Adaptive Immunity to Cancer

Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF- 1

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

The Incidence of Cancer in a Population-Based Cohort of Canadian Heart Transplant Recipients

(2010) Y. Jiang et al.   AMERICAN JOURNAL OF TRANSPLANTATION

B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer

(2010) David J. DiLillo et al.   Annals of the New York Academy of Sciences

Multiple Antitumor Mechanisms Downstream of Prophylactic Regulatory T-Cell Depletion

(2010) Michele W.L. Teng et al.   CANCER RESEARCH

Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma

(2010) Jo Eyles et al.   JOURNAL OF CLINICAL INVESTIGATION

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18

(2010) Rosalba Salcedo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor Immunoediting by NKp46

(2010) M. Elboim et al.   JOURNAL OF IMMUNOLOGY

Lipid accumulation and dendritic cell dysfunction in cancer

(2010) Donna L Herber et al.   NATURE MEDICINE

Tumor-Associated Macrophages and Survival in Classic Hodgkin's Lymphoma

(2010) Christian Steidl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

iNKT Cells Control Mouse Spontaneous Carcinoma Independently of Tumor-Specific Cytotoxic T Cells

(2010) Matteo Bellone et al.   PLoS One

IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis

(2010) M. W. L. Teng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Lymphoidlike Stroma and Immune Escape by Tumors That Express the Chemokine CCL21

(2010) J. D. Shields et al.   SCIENCE

Incidence of and Risk Factors for Skin Cancer After Heart Transplant

(2009) Jerry D. Brewer et al.   ARCHIVES OF DERMATOLOGY

Type I natural killer T cells suppress tumors caused by p53 loss in mice

(2009) J. B. Swann et al.   BLOOD

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

(2009) Michael Hedvat et al.   CANCER CELL

A systematic review of humoral immune responses against tumor antigens

(2009) Miriam Reuschenbach et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

IFN  Promotes Papilloma Development by Up-regulating Th17-Associated Inflammation

(2009) M. Xiao et al.   CANCER RESEARCH

Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine

(2009) M. K. Srivastava et al.   CANCER RESEARCH

IFN-γ-dependent type 1 immunity is crucial for immunosurveillance against squamous cell carcinoma in a novel mouse carcinogenesis model

(2009) Daiko Wakita et al.   CARCINOGENESIS

MK2 regulates the early stages of skin tumor promotion

(2009) Claus Johansen et al.   CARCINOGENESIS

Comparison of de novo tumours after liver transplantation with incidence rates from Italian cancer registries

(2009) U. Baccarani et al.   DIGESTIVE AND LIVER DISEASE

Regulatory T cells: how do they suppress immune responses?

(2009) S. Sakaguchi et al.   INTERNATIONAL IMMUNOLOGY

Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

(2009) Eduardo J Villablanca et al.   NATURE MEDICINE

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Temperature sensitivity of human perforin mutants unmasks subtotal loss of cytotoxicity, delayed FHL, and a predisposition to cancer

(2009) J. Chia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perforin-mediated suppression of B-cell lymphoma

(2009) Paul Bolitho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunosuppressive Regimen Influences Incidence of Skin Cancer in Renal and Pancreatic Transplant Recipients

(2009) Denys J. Loeffelbein et al.   TRANSPLANTATION

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

(2008) K. Movahedi et al.   BLOOD

TNFR1 Signaling and IFN-γ Signaling Determine whether T Cells Induce Tumor Dormancy or Promote Multistage Carcinogenesis

(2008) Nele Müller-Hermelink et al.   CANCER CELL

Antagonistic Roles of CD4+ and CD8+ T-Cells in 7,12-Dimethylbenz(a)anthracene Cutaneous Carcinogenesis

(2008) N. Yusuf et al.   CANCER RESEARCH

NKG2D-Deficient Mice Are Defective in Tumor Surveillance in Models of Spontaneous Malignancy

(2008) Nadia Guerra et al.   IMMUNITY

Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T-lymphocytes and preserved MHC class I antigen expression

(2008) Inge S. van Houdt et al.   INTERNATIONAL JOURNAL OF CANCER

IFN-γ– and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers

(2008) Bin Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development

(2008) Anne Grosse-Wilde et al.   JOURNAL OF CLINICAL INVESTIGATION

TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis

(2008) Niklas Finnberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

(2008) Paul Salama et al.   JOURNAL OF CLINICAL ONCOLOGY

RAGE signaling sustains inflammation and promotes tumor development

(2008) Christoffer Gebhardt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Accelerated tumor growth in mice deficient in DNAM-1 receptor

(2008) Akiko Iguchi-Manaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

“Re-educating” tumor-associated macrophages by targeting NF-κB

(2008) Thorsten Hagemann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Risk of malignant neoplasms after liver transplantation: A population-based study

(2008) Fredrik Åberg et al.   LIVER TRANSPLANTATION

Spontaneous remission of “methotrexate-associated lymphoproliferative disorders” after discontinuation of immunosuppressive treatment for autoimmune disease. Review of the literature

(2008) Rita Rizzi et al.   MEDICAL ONCOLOGY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis

(2008) Jessica Strid et al.   NATURE IMMUNOLOGY

Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D

(2008) Noam Stern-Ginossar et al.   NATURE IMMUNOLOGY

Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase

(2008) A. J. Muller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis

(2008) J. B. Swann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage polarization in tumour progression

(2008) Antonio Sica et al.   SEMINARS IN CANCER BIOLOGY