Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiation

PKM2 coordinates glycolysis with mitochondrial fusion and oxidative phosphorylation

(2019) Tong Li et al.   Protein & Cell

Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics

(2019) Paul T. Brinkkoetter et al.   Cell Reports

A Review of Podocyte Biology

(2018) Puneet Garg   AMERICAN JOURNAL OF NEPHROLOGY

Metabolite regulates differentiation

(2018) Sophie Trefely et al.   SCIENCE

Genetic identification of leptin neural circuits in energy and glucose homeostases

(2018) Jie Xu et al.   NATURE

New Insights into Podocyte Biology in Glomerular Health and Disease

(2017) Suheir Assady et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction

(2017) Weier Qi et al.   NATURE MEDICINE

Mitochondria in aging cell differentiation

(2016) Zdena Palková et al.   Aging-US

Metabolic reprogramming during neuronal differentiation

(2016) M Agostini et al.   CELL DEATH AND DIFFERENTIATION

PKM2, cancer metabolism, and the road ahead

(2016) Talya L Dayton et al.   EMBO REPORTS

Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma

(2016) Talya L. Dayton et al.   GENES & DEVELOPMENT

Metabolic switches during the first steps of adipogenic stem cells differentiation

(2016) Daiana Leila Drehmer et al.   Stem Cell Research

PKM2 and cancer: The function of PKM2 beyond glycolysis

(2016) GAOCHAO DONG et al.   Oncology Letters

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

(2015) Eva M. Palsson-McDermott et al.   Cell Metabolism

Pyruvate kinase M2 at a glance

(2015) W. Yang et al.   JOURNAL OF CELL SCIENCE

Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid

(2015) Christian Kukat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycolysis, but not Mitochondria, responsible for intracellular ATP distribution in cortical area of podocytes

(2015) Shota Ozawa et al.   Scientific Reports

Lactate is always the end product of glycolysis

(2015) Matthew J. Rogatzki et al.   Frontiers in Neuroscience

Mitochondria: from cell death executioners to regulators of cell differentiation

(2014) Atsuko Kasahara et al.   TRENDS IN CELL BIOLOGY

Energy metabolism and energy-sensing pathways in mammalian embryonic and adult stem cell fate

(2013) V. A. Rafalski et al.   JOURNAL OF CELL SCIENCE

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

(2013) Isaline Rowe et al.   NATURE MEDICINE

JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1 -mediated glucose metabolism

(2013) H.-J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Metabolic Plasticity in Stem Cell Homeostasis and Differentiation

(2012) Clifford D.L. Folmes et al.   Cell Stem Cell

Mammalian target of rapamycin signaling in the podocyte

(2012) Ken Inoki et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

(2012) Dimitrios Anastasiou et al.   Nature Chemical Biology

Metabolic checkpoints in activated T cells

(2012) Ruoning Wang et al.   NATURE IMMUNOLOGY

Transcriptional Control of Cellular Metabolism by mTOR Signaling

(2011) J. L. Yecies et al.   CANCER RESEARCH

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells

(2011) Jin Zhang et al.   EMBO JOURNAL

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

(2011) Markus Gödel et al.   JOURNAL OF CLINICAL INVESTIGATION

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2011) Weiwei Yang et al.   NATURE

Bioenergetic characterization of mouse podocytes

(2010) Yoshifusa Abe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

Improvement of mitochondrial energy and oxidative balance during intestinal differentiation

(2010) Francisca M. Santandreu et al.   MITOCHONDRION

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

The engine driving the ship: metabolic steering of cell proliferation and death

(2010) Marisa R. Buchakjian et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Energetic requirements and bioenergetic modulation of mitochondrial morphology and dynamics

(2009) Cécile Sauvanet et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Tetracycline-Inducible Gene Expression in Conditionally Immortalized Mouse Podocytes

(2008) Hiroshi Kajiyama et al.   AMERICAN JOURNAL OF NEPHROLOGY

Transcriptional control of mitochondrial biogenesis: the central role of PGC-1 

(2008) R. Ventura-Clapier et al.   CARDIOVASCULAR RESEARCH

Pyruvate kinase M2 is a phosphotyrosine-binding protein

(2008) Heather R. Christofk et al.   NATURE

Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription

(2007) Jungwoon Lee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY