UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

(2011) Wei Xu et al.   CANCER CELL

Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin

(2011) Vanniarajan Ayyasamy et al.   PLoS One

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

(2010) Maria E. Figueroa et al.   CANCER CELL

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

Tracer-based metabolomics: Concepts and practices

(2010) W-N. Paul Lee et al.   CLINICAL BIOCHEMISTRY

Uncoupling protein UCP2: When mitochondrial activity meets immunity

(2010) Yalin Emre et al.   FEBS LETTERS

Glycolytic network restructuring integral to the energetics of embryonic stem cell cardiac differentiation

(2010) Susan Chung et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells

(2010) Alessandro Prigione et al.   STEM CELLS

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

UCP2, not a physiologically relevant uncoupler but a glucose sparing switch impacting ROS production and glucose sensing

(2009) Frédéric Bouillaud   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial Uncoupling and the Warburg Effect: Molecular Basis for the Reprogramming of Cancer Cell Metabolism

(2009) I. Samudio et al.   CANCER RESEARCH

Distinctions and similarities of cell bioenergetics and the role of mitochondria in hypoxia, cancer, and embryonic development

(2009) Petr Ježek et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

UCP2, a metabolic sensor coupling glucose oxidation to mitochondrial metabolism?

(2009) Claire Pecqueur et al.   IUBMB LIFE

LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer

(2009) H. Xie et al.   MOLECULAR CANCER THERAPEUTICS

Energetic requirements and bioenergetic modulation of mitochondrial morphology and dynamics

(2009) Cécile Sauvanet et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Warburg Effect in Leukemia-Stroma Cocultures Is Mediated by Mitochondrial Uncoupling Associated with Uncoupling Protein 2 Activation

(2008) I. Samudio et al.   CANCER RESEARCH

Regulation of Mitochondrial Structure and Function by the F1Fo-ATPase Inhibitor Protein, IF1

(2008) Michelangelo Campanella et al.   Cell Metabolism

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

A High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells

(2008) Nimet Maherali et al.   Cell Stem Cell

Dimer ribbons of ATP synthase shape the inner mitochondrial membrane

(2008) Mike Strauss et al.   EMBO JOURNAL

Mitochondrial Metabolism Modulates Differentiation and Teratoma Formation Capacity in Mouse Embryonic Stem Cells

(2008) Stefan M. Schieke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Transcriptional and Functional Profiling of Human Embryonic Stem Cell-Derived Cardiomyocytes

(2008) Feng Cao et al.   PLoS One

Generation of human induced pluripotent stem cells from dermal fibroblasts

(2008) W. E. Lowry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization

(2007) Claire Pecqueur et al.   FASEB JOURNAL

Downregulation of Multiple Stress Defense Mechanisms During Differentiation of Human Embryonic Stem Cells

(2007) Gabriele Saretzki et al.   STEM CELLS