d- Versusl-Glucose Conjugation: Mitochondrial Targeting of a Light-Activated Dual-Mode-of-Action Ruthenium-Based Anticancer Prodrug

A Potent Glucose-Platinum Conjugate Exploits Glucose Transporters and Preferentially Accumulates in Cancer Cells

(2016) Malay Patra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An in vitro cell irradiation protocol for testing photopharmaceuticals and the effect of blue, green, and red light on human cancer cell lines

(2016) S. L. Hopkins et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Glucose is a key driver for GLUT1-mediated nanoparticles internalization in breast cancer cells

(2016) Leonardo Venturelli et al.   Scientific Reports

Photoswitching the Cytotoxic Properties of Platinum(II) Compounds

(2015) Andreu Presa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Charged Ruthenium(II) Polypyridyl Complexes as Lysosome-Localized Photosensitizers for Two-Photon Photodynamic Therapy

(2015) Huaiyi Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Excited state investigation of a new Ru(ii) complex for dual reactivity with low energy light

(2015) J. D. Knoll et al.   CHEMICAL COMMUNICATIONS

Molecular basis of ligand recognition and transport by glucose transporters

(2015) Dong Deng et al.   NATURE

Combination of Ru(ii) complexes and light: new frontiers in cancer therapy

(2015) Cristina Mari et al.   Chemical Science

Impact of molecular charge on GLUT-specific cellular uptake of glucose bioprobes and in vivo application of the glucose bioprobe, GB2-Cy3

(2014) Jongmin Park et al.   CHEMICAL COMMUNICATIONS

Quinone–carbohydrate nonglucoside conjugates as a new type of cytotoxic agents: Synthesis and determination of in vitro activity

(2014) Dmitry N. Pelageev et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Carbohydrate-Appended Tumor Targeting Iron(III) Complexes Showing Photocytotoxicity in Red Light

(2014) Uttara Basu et al.   INORGANIC CHEMISTRY

Crystal structure of the human glucose transporter GLUT1

(2014) Dong Deng et al.   NATURE

Synergistic Anti-Cancer Effect of Phenformin and Oxamate

(2014) W. Keith Miskimins et al.   PLoS One

Mitochondria-targeted antioxidant and glycolysis inhibition

(2013) Archana Dilip et al.   ANTI-CANCER DRUGS

Dual Targeting of the Warburg Effect with a Glucose-Conjugated Lactate Dehydrogenase Inhibitor

(2013) Emilia C. Calvaresi et al.   CHEMBIOCHEM

Highly water-soluble platinum(ii) complexes as GLUT substrates for targeted therapy: improved anticancer efficacy and transporter-mediated cytotoxic properties

(2013) Pengxing Liu et al.   CHEMICAL COMMUNICATIONS

The path for metal complexes to a DNA target

(2013) Alexis C. Komor et al.   CHEMICAL COMMUNICATIONS

Carbohydrate-appended photocytotoxic (imidazophenanthroline)-oxovanadium(iv) complexes for cellular targeting and imaging

(2013) Bhabatosh Banik et al.   DALTON TRANSACTIONS

How Do Proximal Hydroxy or Methoxy Groups on the Bidentate Ligand Affect [(2,2′;6′,2"-Terpyridine)Ru(N,N)X] Water-Oxidation Catalysts? Synthesis, Characterization, and Reactivity at Acidic and Near-Neutral pH

(2013) David C. Marelius et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Phosphorescent Cellular Probes and Uptake Indicators Derived from Cyclometalated Iridium(III) Bipyridine Complexes Appended with a Glucose or Galactose Entity

(2013) Wendell Ho-Tin Law et al.   INORGANIC CHEMISTRY

Cellular Toxicity Induced by the Photorelease of a Caged Bioactive Molecule: Design of a Potential Dual-Action Ru(II) Complex

(2013) Mark A. Sgambellone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Glucose conjugation for the specific targeting and treatment of cancer

(2013) Emilia C. Calvaresi et al.   Chemical Science

Luminescent Properties of Ruthenium(II) Complexes with Sterically Expansive Ligands Bound to DNA Defects

(2012) Anna J. McConnell et al.   INORGANIC CHEMISTRY

Strained Ruthenium Complexes Are Potent Light-Activated Anticancer Agents

(2012) Brock S. Howerton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth In Vitro and In Vivo

(2012) Y. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Crystal structures of Λ-[Ru(phen)2dppz]2+ with oligonucleotides containing TA/TA and AT/AT steps show two intercalation modes

(2012) Hakan Niyazi et al.   Nature Chemistry

Crystal structure of Δ-[Ru(bpy)2dppz]2+ bound to mismatched DNA reveals side-by-side metalloinsertion and intercalation

(2012) Hang Song et al.   Nature Chemistry

N-Acetylmethionine and Biotin as Photocleavable Protective Groups for Ruthenium Polypyridyl Complexes

(2011) Roosmarijn E. Goldbach et al.   CHEMISTRY-A EUROPEAN JOURNAL

Light Activation of a Cysteine Protease Inhibitor: Caging of a Peptidomimetic Nitrile with RuII(bpy)2

(2011) Tomasz Respondek et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Potential photoactivated metallopharmaceuticals: from active molecules to supported drugs

(2010) Daniel Crespy et al.   CHEMICAL COMMUNICATIONS

Efficient DNA photocleavage by [Ru(bpy)2(dppn)]2+ with visible light

(2010) Yujie Sun et al.   CHEMICAL COMMUNICATIONS

Photoactivated Biological Activity of Transition-Metal Complexes

(2010) Ulrich Schatzschneider   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Performance of a 99mTc-labelled 1-thio-β-D-glucose 2,3,4,6-tetra-acetate analogue in the detection of infections and tumours in mice: a comparison with [18F]FDG

(2010) Mick M. Welling et al.   NUCLEAR MEDICINE COMMUNICATIONS

New Principles for Glycoside-Bond Formation

(2009) Xiangming Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photoactivated chemotherapy (PACT): the potential of excited-state d-block metals in medicine

(2009) Nicola J. Farrer et al.   DALTON TRANSACTIONS

99m-Technetium carbohydrate conjugates as potential agents in molecular imaging

(2008) Meryn L. Bowen et al.   CHEMICAL COMMUNICATIONS