Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition

Structural basis of chemokine and receptor interactions: Key regulators of leukocyte recruitment in inflammatory responses

(2019) Ram Prasad Bhusal et al.   PROTEIN SCIENCE

Evasins: Tick Salivary Proteins that Inhibit Mammalian Chemokines

(2019) Ram Prasad Bhusal et al.   TRENDS IN BIOCHEMICAL SCIENCES

The solution structure of monomeric CCL5 in complex with a doubly sulfated N-terminal segment of CCR5

(2018) Meital Abayev et al.   FEBS Journal

The N-terminal domain of a tick evasin is critical for chemokine binding and neutralization and confers specific binding activity to other evasins

(2018) James R. O. Eaton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinguishing Sulfotyrosine Containing Peptides from their Phosphotyrosine Counterparts Using Mass Spectrometry

(2018) Guangming Chen et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Mosquito-Derived Anophelin Sulfoproteins Are Potent Antithrombotics

(2018) Emma E. Watson et al.   ACS Central Science

Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

(2017) Yi Zheng et al.   IMMUNITY

Ticks from diverse genera encode chemokine-inhibitory evasin proteins

(2017) Jenni Hayward et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosine sulfation modulates activity of tick-derived thrombin inhibitors

(2017) Robert E. Thompson et al.   Nature Chemistry

Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities

(2017) Kamayani Singh et al.   Scientific Reports

Chemokine binding proteins: An immunomodulatory strategy going viral

(2016) Víctor González-Motos et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Evasins: Therapeutic Potential of a New Family of Chemokine-Binding Proteins from Ticks

(2016) Pauline Bonvin et al.   Frontiers in Immunology

Homogeneous Sulfopeptides and Sulfoproteins: Synthetic Approaches and Applications To Characterize the Effects of Tyrosine Sulfation on Biochemical Function

(2015) Martin J. Stone et al.   ACCOUNTS OF CHEMICAL RESEARCH

Phosphate modulates receptor sulfotyrosine recognition by the chemokine monocyte chemoattractant protein-1 (MCP-1/CCL2)

(2015) Justin P. Ludeman et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Tandem SUMO fusion vectors for improving soluble protein expression and purification

(2015) Fernando Guerrero et al.   PROTEIN EXPRESSION AND PURIFICATION

Total Synthesis of Homogeneous Variants of Hirudin P6: A Post-Translationally Modified Anti-Thrombotic Leech-Derived Protein

(2014) Yves S. Y. Hsieh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Treatment with Evasin-3 abrogates neutrophil-mediated inflammation in mouse acute pancreatitis

(2014) Fabrizio Montecucco et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: The N-Terminal Region of CCR3 Bound to CCL11/Eotaxin-1

(2014) Christopher J. Millard et al.   STRUCTURE

The structural role of receptor tyrosine sulfation in chemokine recognition

(2013) Justin P Ludeman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Tyrosine Sulfation of Chemokine Receptor CCR2 Enhances Interactions with Both Monomeric and Dimeric Forms of the Chemokine Monocyte Chemoattractant Protein-1 (MCP-1)

(2013) Joshua H. Y. Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosylprotein Sulfotransferase-1 and Tyrosine Sulfation of Chemokine Receptor 4 Are Induced by Epstein-Barr Virus Encoded Latent Membrane Protein 1 and Associated with the Metastatic Potential of Human Nasopharyngeal Carcinoma

(2013) Juan Xu et al.   PLoS One

Subversion of cytokine networks by virally encoded decoy receptors

(2012) Megan L. Epperson et al.   IMMUNOLOGICAL REVIEWS

Treatment with Evasin-3 Reduces Atherosclerotic Vulnerability for Ischemic Stroke, but Not Brain Injury in Mice

(2012) Jean-Christophe Copin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Therapeutic Effects of Evasin-1, a Chemokine Binding Protein, in Bleomycin-Induced Pulmonary Fibrosis

(2010) Remo C. Russo et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Analysis of sequence requirements for protein tyrosine sulfation

(2010) Grace L. Rosenquist et al.   PROTEIN SCIENCE

Treatment with a Novel Chemokine-Binding Protein or Eosinophil Lineage-Ablation Protects Mice from Experimental Colitis

(2009) Angélica T. Vieira et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation of Chemokine Recognition by Site-Specific Tyrosine Sulfation of Receptor Peptides

(2009) Levi S. Simpson et al.   CHEMISTRY & BIOLOGY

Chemokines and chemokine receptors: an overview

(2009) Raffaella Bonecchi   Frontiers in Bioscience-Landmark

Tyrosine sulfation: an increasingly recognised post-translational modification of secreted proteins

(2009) Martin J. Stone et al.   New Biotechnology

Structural Basis of Chemokine Sequestration by a Tick Chemokine Binding Protein: The Crystal Structure of the Complex between Evasin-1 and CCL3

(2009) João M. Dias et al.   PLoS One

Ticks produce highly selective chemokine binding proteins with antiinflammatory activity

(2008) Maud Déruaz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chemokine Receptor 2 (CCR2) in Atherosclerosis, Infectious Diseases, and Regulation of T-Cell Polarization

(2003) ISRAEL F. CHARO et al.   MICROCIRCULATION