Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling

Asp1 Bifunctional Activity Modulates Spindle Function via Controlling Cellular Inositol Pyrophosphate Levels in Schizosaccharomyces pombe

(2018) Marina Pascual-Ortiz et al.   MOLECULAR AND CELLULAR BIOLOGY

Mutations in Diphosphoinositol-Pentakisphosphate Kinase PPIP5K2 are associated with hearing loss in human and mouse

(2018) Rizwan Yousaf et al.   PLoS Genetics

KO of 5-InsP7kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotype

(2017) Chunfang Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inositol Pyrophosphate Kinase Asp1 Modulates Chromosome Segregation Fidelity and Spindle Function in Schizosaccharomyces pombe

(2016) Boris Topolski et al.   MOLECULAR AND CELLULAR BIOLOGY

Control of eukaryotic phosphate homeostasis by inositol polyphosphate sensor domains

(2016) R. Wild et al.   SCIENCE

Asp1 from Schizosaccharomyces pombe Binds a [2Fe-2S]2+ Cluster Which Inhibits Inositol Pyrophosphate 1-Phosphatase Activity

(2015) Huanchen Wang et al.   BIOCHEMISTRY

The emerging roles of inositol pyrophosphates in eukaryotic cell physiology

(2015) Swarna Gowri Thota et al.   JOURNAL OF BIOSCIENCES

Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery

(2014) Huanchen Wang et al.   CHEMISTRY & BIOLOGY

The Vip1 Inositol Polyphosphate Kinase Family Regulates Polarized Growth and Modulates the Microtubule Cytoskeleton in Fungi

(2014) Jennifer Pöhlmann et al.   PLoS Genetics

Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response

(2014) Niyas Kudukkil Pulloor et al.   PLoS Pathogens

Inositol pyrophosphates: between signalling and metabolism

(2013) Miranda S. C. Wilson et al.   BIOCHEMICAL JOURNAL

The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment

(2012) Jeremy D. Weaver et al.   BIOSCIENCE REPORTS

Identification of an Evolutionarily Conserved Family of Inorganic Polyphosphate Endopolyphosphatases

(2011) Annalisa Lonetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding

(2011) Huanchen Wang et al.   Nature Chemical Biology

Inositol Pyrophosphates as Mammalian Cell Signals

(2011) A. Chakraborty et al.   Science Signaling

SnapShot: Inositol Phosphates

(2010) Ace J. Hatch et al.   CELL

Asp1, a Conserved 1/3 Inositol Polyphosphate Kinase, Regulates the Dimorphic Switch in Schizosaccharomyces pombe

(2010) J. Pohlmann et al.   MOLECULAR AND CELLULAR BIOLOGY

Inositol Pyrophosphates and Their Unique Metabolic Complexity: Analysis by Gel Electrophoresis

(2009) Oriana Losito et al.   PLoS One

Crystal structure of human diphosphoinositol phosphatase 1

(2009) Ann-Gerd Thorsell et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structural Analysis and Detection of Biological Inositol Pyrophosphates Reveal That the Family of VIP/Diphosphoinositol Pentakisphosphate Kinases Are 1/3-Kinases

(2008) Hongying Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY