Old tricks, new dogs: organocatalytic dienamine activation of α,β-unsaturated aldehydes

Enantioselective Vinylogous Organocascade Reactions

(2016) Hamish B. Hepburn et al.   CHEMICAL RECORD

Remote-Stereocontrol in Dienamine Catalysis: Z-Dienamine Preferences and Electrophile–Catalyst Interaction Revealed by NMR and Computational Studies

(2016) Andreas Seegerer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dienamine-Catalyzed Nitrone Formation via Redox Reaction

(2016) Americo J. Fraboni et al.   ORGANIC LETTERS

Catalytic Enantioselective [5+2] Cycloaddition between Oxidopyrylium Ylides and Enals under Dienamine Activation

(2015) Ane Orue et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric γ-Allylation of α,β-Unsaturated Aldehydes by Combined Organocatalysis and Transition-Metal Catalysis

(2015) Line Naesborg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The stereoselective formation of highly substituted CF3-dihydropyrans as versatile building blocks

(2015) Bjarke S. Donslund et al.   CHEMICAL COMMUNICATIONS

Dienamine and Friedel-Crafts One-Pot Synthesis, and Antitumor Evaluation of Diheteroarylalkanals

(2015) María Frías et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Enamine-Activation of Cyclopropanes for Highly Stereoselective Formation of Cyclobutanes

(2015) Kim Søholm Halskov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Organocatalytic Alkylation of Aldehydes and Enals Driven by the Direct Photoexcitation of Enamines

(2015) Mattia Silvi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric α,γ-Regioselective [3 + 3] Formal Cycloadditions of α,β-Unsaturated Aldehydes via Cascade Dienamine–Dienamine Catalysis

(2015) Wei Xiao et al.   ORGANIC LETTERS

Inter- and Intramolecular Dienamine Organocatalytic Strategies for the Synthesis of Tetrahydroisoquinolines and Tricyclic Derivatives via [3+2] and [4+2] Cycloadditions

(2015) José Alemán et al.   SYNLETT

Construction of Chiral Bridged Tricyclic Benzopyrans: Enantioselective Catalytic Diels-Alder Reaction and a One-Pot Reduction/Acid-Catalyzed Stereoselective Cyclization

(2014) Aiguo Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Construction of Tricyclic Derivatives by the Desymmetrization of Cyclohexadienones

(2014) Cecilia Martín-Santos et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Formation of Steroids

(2014) Kim Søholm Halskov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic–cooperative combination of enamine catalysis with transition metal catalysis

(2014) Yongming Deng et al.   CHEMICAL COMMUNICATIONS

Asymmetric Synthesis of Tetrahydroquinolines through a [3+2] Cycloaddition Controlled by Dienamine Catalysis

(2014) Wenjun Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Access to Enantioenriched Dihydropyran Phosphonates via an Inverse-Electron-Demand Hetero-Diels–Alder Reaction

(2014) Christian F. Weise et al.   JOURNAL OF ORGANIC CHEMISTRY

Control of the Dual Reactivity (Iminium-Dienamine) of β-Arylmethyl α,β-Unsaturated Aldehydes in Organocatalytic 1,3-Dipolar Cycloadditions with N-Benzoyl C,N-Cyclic Azomethine Imines

(2014) Cristina Izquierdo et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Formation of Bridged Benzoxazocines through an Organocatalytic Multicomponent Dienamine-Mediated One-Pot Cascade

(2014) Lars Krogager Ransborg et al.   ORGANIC LETTERS

Asymmetric Synthesis of 3,3′-Spirooxindoles Fused with Cyclobutanes through Organocatalytic Formal [2 + 2] Cycloadditions under H-Bond-Directing Dienamine Activation

(2014) Liang-Wen Qi et al.   ORGANIC LETTERS

Asymmetric organocatalytic functionalization of α,α-disubstituted aldehydes through enamine activation

(2014) Alaric Desmarchelier et al.   TETRAHEDRON

Organocatalytic [4+2] addition reactions via tetraenamine intermediate

(2014) Julian Stiller et al.   Chemical Science

Copper–dienamine catalysis: γ-oxyamination of α,β-unsaturated aldehydes

(2014) Xuan-Huong Ho et al.   Catalysis Science & Technology

Synthesis of Cyclopropane Spirooxindoles by means of a Vinylogous Organocatalytic Cascade

(2014) Rodrigo César da Silva et al.   Asian Journal of Organic Chemistry

Vinylogous Organocatalytic Triple Cascade Reaction: Forging Six Stereocenters in Complex Spiro-Oxindolic Cyclohexanes

(2013) Indranil Chatterjee et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric organocatalysis mediated by α,α-l-diaryl prolinols: recent advances

(2013) Sara Meninno et al.   CHEMICAL COMMUNICATIONS

Organocatalytic asymmetric remote aziridination of 2,4-dienals

(2013) Kim Søholm Halskov et al.   CHEMICAL COMMUNICATIONS

When asymmetric aminocatalysis meets the vinylogy principle

(2013) Igor D. Jurberg et al.   CHEMICAL COMMUNICATIONS

Hydrogen-Bonding in Aminocatalysis: From Proline and Beyond

(2013) Łukasz Albrecht et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Enantioselective Cycloaddition Reactions of Dienamines with Quinones

(2013) Tore Kiilerich Johansen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalyzed Asymmetric Synthesis of Dihydrodibenzofurans Based on a Dienamine Process

(2013) Zi-Yu Wang et al.   ORGANIC LETTERS

Aminocatalytic remote functionalization strategies

(2013) Hao Jiang et al.   Chemical Science

Aminocatalytic Asymmetric Diels–Alder Reactions via HOMO Activation

(2012) Jun-Long Li et al.   ACCOUNTS OF CHEMICAL RESEARCH

Dienamine-Mediated Inverse-Electron-Demand Hetero-Diels-Alder Reaction by Using an Enantioselective H-Bond-Directing Strategy

(2012) Łukasz Albrecht et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Cyclobutanes by a Formal [2+2] Cycloaddition Controlled by Dienamine Catalysis

(2012) Alejandro Parra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Dienamine/Hydrogen-Bonding Catalysis: Enantioselective Formal [2+2] Cycloaddition of Enals with Nitroalkenes

(2012) Garazi Talavera et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalyzed Michael–Henry reactions: enantioselective synthesis of cyclopentanecarbaldehydes via the dienamine organocatalysis of a succinaldehyde surrogate

(2012) Bor-Cherng Hong et al.   CHEMICAL COMMUNICATIONS

A remarkably simple α-oximation of aldehydes via organo-SOMO catalysis

(2012) Patrizia Gentili et al.   CHEMICAL COMMUNICATIONS

Applications of asymmetric organocatalysis in medicinal chemistry

(2012) José Alemán et al.   CHEMICAL SOCIETY REVIEWS

Secondary Amine-Catalyzed Asymmetricγ-Alkylation ofα-Branched EnalsviaDienamine Activation

(2012) Mattia Silvi et al.   HELVETICA CHIMICA ACTA

Enantioselective Organocatalytic Intramolecular Diels–Alder Reactions: A Computational Study

(2012) Filipe J. S. Duarte et al.   JOURNAL OF ORGANIC CHEMISTRY

γ-Amino Alcohols via Organocascade Reactions Involving Dienamine Catalysis

(2012) Chandrakumar Appayee et al.   JOURNAL OF ORGANIC CHEMISTRY

Curtin–Hammett Paradigm for Stereocontrol in Organocatalysis by Diarylprolinol Ether Catalysts

(2012) Jordi Burés et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Organocatalytic Formal [2 + 2]-Cycloadditions via Bifunctional H-Bond Directing Dienamine Catalysis

(2012) Łukasz Albrecht et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric trienamine catalysis: new opportunities in amine catalysis

(2012) Indresh Kumar et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantio- and Diastereoselective Synthesis of Substituted Tetrahydro-1H-isochromanes through a Dynamic Kinetic Resolution Proceeding under Dienamine Catalysis

(2012) Ane Orue et al.   ORGANIC LETTERS

Direct Catalytic Enantioselective Vinylogous Aldol Reaction of α-Branched Enals with Isatins

(2012) Carlo Cassani et al.   ORGANIC LETTERS

Cooperative Catalytic Reactions Using Organocatalysts and Transition Metal Catalysts: Propargylic Allylation of Propargylic Alcohols with α,β-Unsaturated Aldehydes

(2012) Masahiro Ikeda et al.   ORGANOMETALLICS

Asymmetric Diels–Alder reaction of β,β-disubstituted enals and chromone-fused dienes: construction of collections with high molecular complexity and skeletal diversity

(2012) Jun-Long Li et al.   Chemical Science

Unique properties of chiral biaryl-based secondary aminecatalysts for asymmetric enamine catalysis

(2012) Taichi Kano et al.   Chemical Science

The Diarylprolinol Silyl Ether System: A General Organocatalyst

(2011) Kim L. Jensen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Quantum Mechanical Investigations of Organocatalysis: Mechanisms, Reactivities, and Selectivities

(2011) Paul Ha-Yeon Cheong et al.   CHEMICAL REVIEWS

Dienamine Activation in the Organocatalytic Asymmetric Synthesis of cis-3,4-Difunctionalized Chromans and Dihydrocoumarins

(2011) Dieter Enders et al.   Chemistry-An Asian Journal

Dienamine Catalysis: An Emerging Technology in Organic Synthesis

(2011) Dhevalapally B. Ramachary et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalyzed Michael Addition of Aldehydes to Nitro Alkenes - Generally Accepted Mechanism Revisited and Revised

(2011) Krystyna Patora-Komisarska et al.   HELVETICA CHIMICA ACTA

Mechanistic Rationalization of Organocatalyzed Conjugate Addition of Linear Aldehydes to Nitro-olefins

(2011) Jordi Burés et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The intramolecular asymmetric allylation of aldehydes via organo-SOMO catalysis: A novel approach to ring construction

(2011) Phong V. Pham et al.   Chemical Science

Organocatalytic Asymmetric Inverse-Electron-Demand Diels-Alder Reaction of Electron-Deficient Dienes and Crotonaldehyde

(2010) Jun-Long Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lewis Acid Catalyzed Intramolecular Direct Ene Reaction of Indoles

(2010) Bo Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Organocatalysis for the Asymmetric γ Alkylation of α-Branched Enals

(2010) Giulia Bergonzini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanisms in aminocatalysis

(2010) Martin Nielsen et al.   CHEMICAL COMMUNICATIONS

Concerning the Mechanism of the FeCl3-Catalyzed α-Oxyamination of Aldehydes: Evidence for a Non-SOMO Activation Pathway

(2010) Jeffrey F. Van Humbeck et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric organocatalysis in total synthesis – a trial by fire

(2010) Eugenia Marqués-López et al.   NATURAL PRODUCT REPORTS

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

Enantioselective α- and γ-Alkylation of α,β-Unsaturated Aldehydes Using Dienamine Activation

(2010) Julian Stiller et al.   ORGANIC LETTERS

Organocatalytic Regio- and Stereoselective Inverse-Electron-Demand Aza-Diels-Alder Reaction of α,β-Unsaturated Aldehydes andN-Tosyl-1-aza-1,3-butadienes

(2009) Bo Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Light in Aminocatalysis: The Asymmetric Intermolecular α-Alkylation of Aldehydes

(2009) Paolo Melchiorre   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conjugated imines and iminium salts as versatile acceptors of nucleophiles

(2009) Makoto Shimizu et al.   CHEMICAL COMMUNICATIONS

Organocatalysis—after the gold rush

(2009) Søren Bertelsen et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective α-Trifluoromethylation of Aldehydes via Photoredox Organocatalysis

(2009) David A. Nagib et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crossed Intramolecular Rauhut−Currier-Type Reactions via Dienamine Activation

(2009) Eugenia Marqués-López et al.   ORGANIC LETTERS

Asymmetric Michael Addition of γ,γ-Disubstituted α,β-Unsaturated Aldehydes to Nitroolefins via Dienamine Catalysis

(2009) Bo Han et al.   ORGANIC LETTERS

Amine-Catalyzed Cyclizations of Tethered α,β-Unsaturated Carbonyl Compounds

(2008) Renata Marcia de Figueiredo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Seven‐Membered Rings by Cyclization at Transition Metals: [4+3], [3+2+2], [5+2]

(2008) Holger Butenschön   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

α,α-Diarylprolinol Ethers: New Tools for Functionalization of Carbonyl Compounds

(2008) Antonia Mielgo et al.   Chemistry-An Asian Journal

The advent and development of organocatalysis

(2008) David W. C. MacMillan   NATURE

Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes

(2008) D. A. Nicewicz et al.   SCIENCE