期刊
CHEMICAL SCIENCE
卷 2, 期 8, 页码 1470-1473出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1sc00176k
关键词
-
资金
- NIHGMS [R01 GM078201-05]
- Vietnamese government
- Merck
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM078201] Funding Source: NIH RePORTER
The intramolecular asymmetric cyclization of aldehydes has been accomplished using singly occupied molecular orbital (SOMO) catalysis. Selective oxidation of chiral enamines (formed by the condensation of an aldehyde and a secondary amine catalyst) leads to the formation of a 3 pi-electron radical species. These chiral SOMO-activated radical cations undergo enantioselective cyclization with an array of pendent allylsilanes thus efficiently providing a new approach to the construction of five-, six- and seven-membered carbocycles and heterocycles.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据