SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia
出版年份 2020 全文链接
标题
SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia
作者
关键词
-
出版物
LEUKEMIA
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-05-07
DOI
10.1038/s41375-020-0845-6
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Dietary methionine influences therapy in mouse cancer models and alters human metabolism
- (2019) Xia Gao et al. NATURE
- Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia
- (2018) Nikos Kourtis et al. NATURE MEDICINE
- Mitochondrial One-Carbon Pathway Supports Cytosolic Folate Integrity in Cancer Cells
- (2018) Yuxiang Zheng et al. CELL
- Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma
- (2017) Gregory S. Ducker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Acute lymphoblastic leukemia: a comprehensive review and 2017 update
- (2017) T Terwilliger et al. Blood Cancer Journal
- Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway
- (2016) Gregory S. Ducker et al. Cell Metabolism
- Targeting MTHFD2 in acute myeloid leukemia
- (2016) Yana Pikman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells
- (2016) Oliver D.K. Maddocks et al. MOLECULAR CELL
- mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle
- (2016) I. Ben-Sahra et al. SCIENCE
- How I treat T-cell acute lymphoblastic leukemia in adults
- (2015) M. R. Litzow et al. BLOOD
- Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism
- (2015) Samantha J. Mentch et al. Cell Metabolism
- Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia
- (2015) Daniel Herranz et al. NATURE MEDICINE
- Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes
- (2014) G. Y. Lee et al. CANCER RESEARCH
- Quantitative flux analysis reveals folate-dependent NADPH production
- (2014) Jing Fan et al. NATURE
- Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
- (2014) Panagiotis Ntziachristos et al. NATURE
- A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia
- (2014) Daniel Herranz et al. NATURE MEDICINE
- Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia
- (2014) J. Ye et al. Cancer Discovery
- Serine, but Not Glycine, Supports One-Carbon Metabolism and Proliferation of Cancer Cells
- (2014) Christiaan F. Labuschagne et al. Cell Reports
- Acute lymphoblastic leukaemia
- (2013) Hiroto Inaba et al. LANCET
- The molecular basis of T cell acute lymphoblastic leukemia
- (2012) Pieter Van Vlierberghe et al. JOURNAL OF CLINICAL INVESTIGATION
- Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells
- (2012) Oliver D. K. Maddocks et al. NATURE
- Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells
- (2012) Wanjuan Yang et al. NUCLEIC ACIDS RESEARCH
- Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
- (2012) M. Jain et al. SCIENCE
- Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism
- (2010) Anne S. Tibbetts et al. Annual Review of Nutrition
- Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras–initiated leukemia
- (2008) Mark Y. Chiang et al. JOURNAL OF CLINICAL INVESTIGATION
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