标题
Thalidomide-induced teratogenesis: History and mechanisms
作者
关键词
-
出版物
BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS
Volume 105, Issue 2, Pages 140-156
出版商
Wiley
发表日期
2015-06-04
DOI
10.1002/bdrc.21096
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Thalidomide (5HPP-33) Suppresses Microtubule Dynamics and Depolymerizes the Microtubule Network by Binding at the Vinblastine Binding Site on Tubulin
- (2015) Aijaz Rashid et al. BIOCHEMISTRY
- Effect of maternal diabetes on the embryo, fetus, and children: Congenital anomalies, genetic and epigenetic changes and developmental outcomes
- (2015) Asher Ornoy et al. BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS
- Inhibition of Endothelial Slit2/Robo1 Signaling by Thalidomide Restrains Angiogenesis by Blocking the PI3K/Akt Pathway
- (2014) Yinan Li et al. DIGESTIVE DISEASES AND SCIENCES
- Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression
- (2014) Xiaohan Zhao et al. HUMAN MOLECULAR GENETICS
- Thalidomide mimics uridine binding to an aromatic cage in cereblon
- (2014) Marcus D. Hartmann et al. JOURNAL OF STRUCTURAL BIOLOGY
- Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
- (2014) Anjali P. Kusumbe et al. NATURE
- Endothelial Notch activity promotes angiogenesis and osteogenesis in bone
- (2014) Saravana K. Ramasamy et al. NATURE
- Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs
- (2014) Philip P Chamberlain et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Transcriptomic Characterization of C57BL/6 Mouse Embryonic Stem Cell Differentiation and Its Modulation by Developmental Toxicants
- (2014) Xiugong Gao et al. PLoS One
- Recognition of the phenotype of thalidomide embryopathy in countries endemic for leprosy
- (2013) Fernanda S.L. Vianna et al. CLINICAL DYSMORPHOLOGY
- Disruption of the Cereblon Gene Enhances Hepatic AMPK Activity and Prevents High-Fat Diet-Induced Obesity and Insulin Resistance in Mice
- (2013) K. M. Lee et al. DIABETES
- Molecular analysis of regulative events in the developing chick limb
- (2013) Chris Mahony et al. JOURNAL OF ANATOMY
- Thalidomide-induced angiopoietin 2, Notch1 and Dll4 downregulation under hypoxic condition in tissues with gastrointestinal vascular malformation and human umbilical vein endothelial cells
- (2013) Qian Feng et al. Journal of Digestive Diseases
- Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration
- (2013) Nick R. Love et al. NATURE CELL BIOLOGY
- Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro
- (2013) C. Mahony et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
- (2013) J. Kronke et al. SCIENCE
- The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
- (2013) G. Lu et al. SCIENCE
- Identification of Thalidomide-Specific Transcriptomics and Proteomics Signatures during Differentiation of Human Embryonic Stem Cells
- (2012) Kesavan Meganathan et al. PLoS One
- Redox control of teratogenesis
- (2012) Jason M. Hansen et al. REPRODUCTIVE TOXICOLOGY
- Nitric oxide rescues thalidomide mediated teratogenicity
- (2012) Jamila H. Siamwala et al. Scientific Reports
- The non-redundant function of cohesin acetyltransferase Esco2
- (2012) Gabriela Whelan et al. Nucleus
- Genome-wide analysis of gene expression during Xenopus tropicalis tadpole tail regeneration
- (2011) Nick R Love et al. BMC DEVELOPMENTAL BIOLOGY
- Teratogenic effects of thalidomide: molecular mechanisms
- (2011) Takumi Ito et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- What can we learn from the thalidomide experience
- (2011) Marilyn T. Miller et al. CURRENT OPINION IN OPHTHALMOLOGY
- Embryopathic effects of thalidomide and its hydrolysis products in rabbit embryo culture: evidence for a prostaglandin H synthase (PHS)-dependent, reactive oxygen species (ROS)-mediated mechanism
- (2011) Crystal J. J. Lee et al. FASEB JOURNAL
- A Zebrafish Model of Roberts Syndrome Reveals That Esco2 Depletion Interferes with Development by Disrupting the Cell Cycle
- (2011) Maren Mönnich et al. PLoS One
- Racemates revisited: heterochiral assemblies and the example ofdl-thalidomide
- (2011) David E. Hague et al. XENOBIOTICA
- Apoptosis Induction by Thalidomide: Critical for Limb Teratogenicity but Therapeutic Potential in Idiopathic Pulmonary Fibrosis?
- (2011) Jurgen Knobloch et al. Current Molecular Pharmacology
- Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia
- (2010) Franck Lebrin et al. NATURE MEDICINE
- Identification of a Primary Target of Thalidomide Teratogenicity
- (2010) T. Ito et al. SCIENCE
- Thalidomide-induced limb defects: resolving a 50-year-old puzzle
- (2009) Neil Vargesson BIOESSAYS
- Thalidomide and misoprostol: Ophthalmologic manifestations and associations both expected and unexpected
- (2009) Marilyn T. Miller et al. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY
- Thalidomide attenuates nitric oxide-driven angiogenesis by interacting with soluble guanylyl cyclase
- (2009) Syamantak Majumder et al. BRITISH JOURNAL OF PHARMACOLOGY
- History, heresy and radiology in scientific discovery
- (2009) J McCredie Journal of Medical Imaging and Radiation Oncology
- Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation
- (2009) C. Therapontos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fetal malformations and early embryonic gene expression response in cynomolgus monkeys maternally exposed to thalidomide☆
- (2009) Makoto Ema et al. REPRODUCTIVE TOXICOLOGY
- Oxidative Stress in Developmental Origins of Disease: Teratogenesis, Neurodevelopmental Deficits, and Cancer
- (2009) Peter G. Wells et al. TOXICOLOGICAL SCIENCES
- Genetic evidence that FGFs have an instructive role in limb proximal–distal patterning
- (2008) Francesca V. Mariani et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started