E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases

The transcription factor NFIL3 controls regulatory T-cell function and stability

(2019) Hyeong Su Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses

(2019) Rachel L. Clement et al.   NATURE IMMUNOLOGY

MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation

(2018) Ruifang Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

Multiple Levels of Control Determine How E4bp4/Nfil3 Regulates NK Cell Development

(2018) Tomasz Kostrzewski et al.   JOURNAL OF IMMUNOLOGY

IL-6/STAT3 pathway induced deficiency of RFX1 contributes to Th17-dependent autoimmune diseases via epigenetic regulation

(2018) Ming Zhao et al.   Nature Communications

The Ratio of Blood T Follicular Regulatory Cells to T Follicular Helper Cells Marks Ectopic Lymphoid Structure Formation While Activated Follicular Helper T Cells Indicate Disease Activity in Primary Sjögren's Syndrome

(2018) Valter R. Fonseca et al.   Arthritis & Rheumatology

Uncovering the Role of RNA-Binding Proteins in Gene Expression in the Immune System

(2018) Manuel D. Díaz-Muñoz et al.   Frontiers in Immunology

HDAC11 regulates interleukin-13 expression in CD4+ T cells in the heart

(2018) Li Yuan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Posttranscriptional Gene Regulation of T Follicular Helper Cells by RNA-Binding Proteins and microRNAs

(2018) Dirk Baumjohann et al.   Frontiers in Immunology

The expression of Bcl-6 in circulating follicular helper-like T cells positively correlates with the disease activity in systemic lupus erythematosus

(2016) Xin Huang et al.   CLINICAL IMMUNOLOGY

T follicular regulatory cells

(2016) Peter T. Sage et al.   IMMUNOLOGICAL REVIEWS

TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus

(2016) Lukas Bossaller et al.   JOURNAL OF IMMUNOLOGY

Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses

(2015) Mauricio F. Farez et al.   CELL

Increased frequency of circulating follicular helper T cells in lupus patients is associated with autoantibody production in a CD40L-dependent manner

(2015) Huaheng Xu et al.   CELLULAR IMMUNOLOGY

OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response

(2015) Clément Jacquemin et al.   IMMUNITY

The transcription factor TCF-1 initiates the differentiation of TFH cells during acute viral infection

(2015) Lifan Xu et al.   NATURE IMMUNOLOGY

Emerging role of IL-17 and Th17 cells in systemic lupus erythematosus

(2014) Jérôme C. Martin et al.   CLINICAL IMMUNOLOGY

T Follicular Helper Cell Differentiation, Function, and Roles in Disease

(2014) Shane Crotty   IMMUNITY

TGF-β prevents T follicular helper cell accumulation and B cell autoreactivity

(2014) Mark J. McCarron et al.   JOURNAL OF CLINICAL INVESTIGATION

Circulating T follicular regulatory and helper cells have memory-like properties

(2014) Peter T. Sage et al.   JOURNAL OF CLINICAL INVESTIGATION

The calcium feedback loop and T cell activation: How cytoskeleton networks control intracellular calcium flux

(2013) Noah Joseph et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Transcriptional regulation of follicular T-helper (Tfh) cells

(2013) Xindong Liu et al.   IMMUNOLOGICAL REVIEWS

E4BP4 overexpression: A protective mechanism in CD4+ T cells from SLE patients

(2013) Ming Zhao et al.   JOURNAL OF AUTOIMMUNITY

TH17 Cell Differentiation Is Regulated by the Circadian Clock

(2013) X. Yu et al.   SCIENCE

Th17 Cells

(2012) Mohan S. Maddur et al.   AMERICAN JOURNAL OF PATHOLOGY

SOCS3 promotes interleukin-17 expression of human T cells

(2012) K. Kleinsteuber et al.   BLOOD

The darker side of follicular helper T cells: from autoimmunity to immunodeficiency

(2012) Sudhanshu Shekhar et al.   Cellular & Molecular Immunology

Immune-Regulatory Mechanisms in Systemic Autoimmune and Rheumatic Diseases

(2012) Britt Nakken et al.   Clinical & Developmental Immunology

The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood

(2012) Peter T Sage et al.   NATURE IMMUNOLOGY

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

NFIL3/E4BP4 controls type 2 T helper cell cytokine expression

(2011) Masaki Kashiwada et al.   EMBO JOURNAL

Functional and Epigenetic Studies Reveal Multistep Differentiation and Plasticity of In Vitro-Generated and In Vivo-Derived Follicular T Helper Cells

(2011) Kristina T. Lu et al.   IMMUNITY

T regulatory cells participate in the control of germinal centre reactions

(2011) Carla-Maria Alexander et al.   IMMUNOLOGY

The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns

(2011) Kenneth J. Oestreich et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NFIL3 Is a Regulator of IL-12 p40 in Macrophages and Mucosal Immunity

(2011) T. Kobayashi et al.   JOURNAL OF IMMUNOLOGY

Regulation of the Germinal Center Reaction by Foxp3+ Follicular Regulatory T Cells

(2011) I. Wollenberg et al.   JOURNAL OF IMMUNOLOGY

The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells

(2011) Yasutaka Motomura et al.   NATURE IMMUNOLOGY

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

(2011) Yeonseok Chung et al.   NATURE MEDICINE

Foxp3+ follicular regulatory T cells control the germinal center response

(2011) Michelle A Linterman et al.   NATURE MEDICINE

Multiple checkpoints keep follicular helper T cells under control to prevent autoimmunity

(2010) Di Yu et al.   Cellular & Molecular Immunology

Epigenetics and SLE: RFX1 downregulation causes CD11a and CD70 overexpression by altering epigenetic modifications in lupus CD4+ T cells

(2010) Ming Zhao et al.   JOURNAL OF AUTOIMMUNITY

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections

(2009) Tsvetelina Pentcheva-Hoang et al.   IMMUNOLOGICAL REVIEWS

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12

(2009) Cindy S Ma et al.   IMMUNOLOGY AND CELL BIOLOGY

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

(2009) Shintaro Kamizono et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TGF-  Promotes Th17 Cell Development through Inhibition of SOCS3

(2009) H. Qin et al.   JOURNAL OF IMMUNOLOGY

The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development

(2009) Duncan M Gascoyne et al.   NATURE IMMUNOLOGY

IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching

(2009) M. Kashiwada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of autoimmunity by pristane and other naturally occurring hydrocarbons

(2009) Westley H. Reeves et al.   TRENDS IN IMMUNOLOGY

IL-17 and the Th17 lineage in systemic lupus erythematosus

(2008) Lee Ann Garrett-Sinha et al.   CURRENT OPINION IN RHEUMATOLOGY

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

(2008) Roza I. Nurieva et al.   IMMUNITY