The transcription factor NFIL3 controls regulatory T-cell function and stability

The STAT3/NFIL3 signaling axis-mediated chemotherapy resistance is reversed by Raddeanin A via inducing apoptosis in choriocarcinoma cells

(2018) Zheng Peng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CD69 enhances immunosuppressive function of regulatory T-cells and attenuates colitis by prompting IL-10 production

(2018) Lei Yu et al.   Cell Death & Disease

Inflammation-induced Id2 promotes plasticity in regulatory T cells

(2018) Sung-Min Hwang et al.   Nature Communications

PTEN drives Th17 cell differentiation by preventing IL-2 production

(2017) Hyeong Su Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Plasticity and Stability of Regulatory T Cells during Viral-Induced Inflammatory Lesions

(2017) Siddheshvar Bhela et al.   JOURNAL OF IMMUNOLOGY

Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development

(2017) Patrick Ming-Kuen Tang et al.   Nature Communications

Functional defects in CD4+ CD25high FoxP3+ regulatory cells in ankylosing spondylitis

(2016) Huifang Guo et al.   Scientific Reports

MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis

(2015) Gopal Murugaiyan et al.   JOURNAL OF CLINICAL INVESTIGATION

Glucocorticoid-Induced Tumour Necrosis Factor Receptor-Related Protein: A Key Marker of Functional Regulatory T Cells

(2015) Simona Ronchetti et al.   Journal of Immunology Research

NFIL3-Deficient Mice Develop Microbiota-Dependent, IL-12/23-Driven Spontaneous Colitis

(2014) T. Kobayashi et al.   JOURNAL OF IMMUNOLOGY

Survival factor NFIL3 restricts FOXO-induced gene expression in cancer

(2013) M. Keniry et al.   GENES & DEVELOPMENT

The Role of FOXP3 in Regulating Immune Responses

(2013) Jens Vent-Schmidt et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Recruitment of Histone Methyltransferase G9a Mediates Transcriptional Repression ofFgf21Gene by E4BP4 Protein

(2013) Xin Tong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TH17 Cell Differentiation Is Regulated by the Circadian Clock

(2013) X. Yu et al.   SCIENCE

Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

(2012) Takahisa Miyao et al.   IMMUNITY

Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut

(2012) Susan M. Schlenner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ICOS-Dependent Homeostasis and Function of Foxp3+ Regulatory T Cells in Islets of Nonobese Diabetic Mice

(2012) M. Kornete et al.   JOURNAL OF IMMUNOLOGY

NFIL3/E4BP4 controls type 2 T helper cell cytokine expression

(2011) Masaki Kashiwada et al.   EMBO JOURNAL

Cellular DBP and E4BP4 proteins are critical for determining the period length of the circadian oscillator

(2011) Daisuke Yamajuku et al.   FEBS LETTERS

The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells

(2011) Yasutaka Motomura et al.   NATURE IMMUNOLOGY

Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease

(2011) Margarita Dominguez-Villar et al.   NATURE MEDICINE

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Positive and Negative Transcriptional Regulation of the Foxp3 Gene is Mediated by Access and Binding of the Smad3 Protein to Enhancer I

(2010) Lili Xu et al.   IMMUNITY

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

(2010) Ye Zheng et al.   NATURE

Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions

(2009) João H. Duarte et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

(2009) Shintaro Kamizono et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development

(2009) Duncan M Gascoyne et al.   NATURE IMMUNOLOGY

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching

(2009) M. Kashiwada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs

(2008) Xuexian O. Yang et al.   IMMUNITY

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology