Noncanonical regulation of phosphatidylserine metabolism by a Sec14-like protein and a lipid kinase

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

An equal opportunity collaboration between lipid metabolism and proteins in the control of membrane trafficking in the trans-Golgi and endosomal systems

(2019) Yaxi Wang et al.   CURRENT OPINION IN CELL BIOLOGY

High-Coverage Targeted Lipidomics Reveals Novel Serum Lipid Predictors and Lipid Pathway Dysregulation Antecedent to Type 2 Diabetes Onset in Normoglycemic Chinese Adults

(2019) Jieli Lu et al.   DIABETES CARE

Functional diversification of the chemical landscapes of yeast Sec14-like phosphatidylinositol transfer protein lipid-binding cavities

(2019) Ashutosh Tripathi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis

(2018) Zhigang Xie et al.   DEVELOPMENTAL CELL

A Lipid Transfer Protein Signaling Axis Exerts Dual Control of Cell-Cycle and Membrane Trafficking Systems

(2018) Jin Huang et al.   DEVELOPMENTAL CELL

Oxysterol-binding protein homologs mediate sterol transport from the endoplasmic reticulum to mitochondria in yeast

(2018) Siqi Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact

(2018) Nadav Shai et al.   Nature Communications

Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation

(2018) Evan Quon et al.   PLOS BIOLOGY

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites

(2018) Nikit Kumar et al.   JOURNAL OF CELL BIOLOGY

Here, there, and everywhere: The importance of ER membrane contact sites

(2018) Haoxi Wu et al.   SCIENCE

Dynamics and energetics of the mammalian phosphatidylinositol transfer protein phospholipid exchange cycle

(2017) Aby Grabon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation

(2017) Michal Eisenberg-Bord et al.   JOURNAL OF CELL BIOLOGY

The Vps13p–Cdc31p complex is directly required for TGN late endosome transport and TGN homotypic fusion

(2017) Mithu De et al.   JOURNAL OF CELL BIOLOGY

Regulation of lipid droplets by metabolically controlled Ldo isoforms

(2017) Vitor Teixeira et al.   JOURNAL OF CELL BIOLOGY

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

(2017) Alex M. Valm et al.   NATURE

Two-ligand priming mechanism for potentiated phosphoinositide synthesis is an evolutionarily conserved feature of Sec14-like phosphatidylinositol and phosphatidylcholine exchange proteins

(2016) Jin Huang et al.   MOLECULAR BIOLOGY OF THE CELL

Plasticity of PI4KIII  interactions at the plasma membrane

(2015) J. Chung et al.   EMBO REPORTS

Ltc1 is an ER-localized sterol transporter and a component of ER–mitochondria and ER–vacuole contacts

(2015) Andrew Murley et al.   JOURNAL OF CELL BIOLOGY

The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane

(2015) Jeremy M. Baskin et al.   NATURE CELL BIOLOGY

Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate

(2015) J. Moser von Filseck et al.   SCIENCE

PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts

(2015) J. Chung et al.   SCIENCE

Lam6 Regulates the Extent of Contacts between Organelles

(2015) Yael Elbaz-Alon et al.   Cell Reports

Arabidopsis AtPLC2 Is a Primary Phosphoinositide-Specific Phospholipase C in Phosphoinositide Metabolism and the Endoplasmic Reticulum Stress Response

(2015) Kazue Kanehara et al.   PLoS Genetics

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

(2015) Alberto T Gatta et al.   eLife

A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress–induced membrane biogenesis

(2014) Jihui Ren et al.   MOLECULAR BIOLOGY OF THE CELL

Involvement of Sac1 phosphoinositide phosphatase in the metabolism of phosphatidylserine in the yeastSaccharomyces cerevisiae

(2014) Motohiro Tani et al.   YEAST

An Assembly of Proteins and Lipid Domains Regulates Transport of Phosphatidylserine to Phosphatidylserine Decarboxylase 2 inSaccharomyces cerevisiae

(2013) Wayne R. Riekhof et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PITPs as targets for selectively interfering with phosphoinositide signaling in cells

(2013) Aaron H Nile et al.   Nature Chemical Biology

ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology

(2012) Andrew G. Manford et al.   DEVELOPMENTAL CELL

PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity

(2012) Fubito Nakatsu et al.   JOURNAL OF CELL BIOLOGY

Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites

(2011) Christopher J. Stefan et al.   CELL

The Diverse Functions of Oxysterol-Binding Proteins

(2010) Sumana Raychaudhuri et al.   Annual Review of Cell and Developmental Biology

Zebrafish Class 1 Phosphatidylinositol Transfer Proteins: PITPβ and Double Cone Cell Outer Segment Integrity in Retina

(2010) Kristina E. Ile et al.   TRAFFIC

Coordination of Golgi functions by phosphatidylinositol 4-kinases

(2010) Todd R. Graham et al.   TRENDS IN CELL BIOLOGY

Compartment-specific Synthesis of Phosphatidylethanolamine Is Required for Normal Heavy Metal Resistance

(2009) Kailash Gulshan et al.   MOLECULAR BIOLOGY OF THE CELL

The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signaling

(2009) Vytas A. Bankaitis et al.   TRENDS IN BIOCHEMICAL SCIENCES

Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3

(2008) Dan Baird et al.   JOURNAL OF CELL BIOLOGY

Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily

(2008) Gabriel Schaaf et al.   MOLECULAR CELL