Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation

Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites

(2018) Junsen Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Speed Limits for Nonvesicular Intracellular Sterol Transport

(2017) Jeremy S. Dittman et al.   TRENDS IN BIOCHEMICAL SCIENCES

Piecing Together the Patchwork of Contact Sites

(2017) Alberto T. Gatta et al.   TRENDS IN CELL BIOLOGY

Endoplasmic Reticulum–Plasma Membrane Associations:Structures and Functions

(2016) Alessandra Gallo et al.   Annual Review of Cell and Developmental Biology

Phosphoinositides in membrane contact sites

(2016) Camilla Raiborg et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Lipid transfer proteins do their thing anchored at membrane contact sites… but what is their thing?

(2016) Louise H. Wong et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

SMP-domain proteins at membrane contact sites: Structure and function

(2016) Karin M. Reinisch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Structural insights into nonvesicular lipid transport by the oxysterol binding protein homologue family

(2016) Junsen Tong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

VAP, a Versatile Access Point for the Endoplasmic Reticulum: Review and analysis of FFAT-like motifs in the VAPome

(2016) Sarah E. Murphy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A Tether Is a Tether Is a Tether: Tethering at Membrane Contact Sites

(2016) Michal Eisenberg-Bord et al.   DEVELOPMENTAL CELL

Dynamic formation of ER–PM junctions presents a lipid phosphatase to regulate phosphoinositides

(2016) Eamonn J. Dickson et al.   JOURNAL OF CELL BIOLOGY

Control of plasma membrane lipid homeostasis by the extended synaptotagmins

(2016) Yasunori Saheki et al.   NATURE CELL BIOLOGY

Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction

(2016) Alessandra Sclip et al.   PLoS One

Polarized Exocytosis Induces Compensatory Endocytosis by Sec4p-Regulated Cortical Actin Polymerization

(2016) Jesper Johansen et al.   PLOS BIOLOGY

Untargeted UPLC-MS Profiling Pipeline to Expand Tissue Metabolome Coverage: Application to Cardiovascular Disease

(2015) Panagiotis A. Vorkas et al.   ANALYTICAL CHEMISTRY

Building a patchwork — The yeast plasma membrane as model to study lateral domain formation

(2015) Christian Schuberth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ATP-binding cassette transporters and sterol O-acyltransferases interact at membrane microdomains to modulate sterol uptake and esterification

(2015) Sonia Gulati et al.   FASEB JOURNAL

Ltc1 is an ER-localized sterol transporter and a component of ER–mitochondria and ER–vacuole contacts

(2015) Andrew Murley et al.   JOURNAL OF CELL BIOLOGY

Countercurrents in lipid flow

(2015) Anant K. Menon et al.   NATURE

Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate

(2015) J. Moser von Filseck et al.   SCIENCE

A phosphatidylinositol-4-phosphate powered exchange mechanism to create a lipid gradient between membranes

(2015) Joachim Moser von Filseck et al.   Nature Communications

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

(2015) Alberto T Gatta et al.   eLife

Lipid landscapes and pipelines in membrane homeostasis

(2014) Joost C.M. Holthuis et al.   NATURE

An ER Protein Functionally Couples Neutral Lipid Metabolism on Lipid Droplets to Membrane Lipid Synthesis in the ER

(2014) Daniel F. Markgraf et al.   Cell Reports

START ships lipids across interorganelle space

(2013) Fabien Alpy et al.   BIOCHIMIE

PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

(2013) Francesca Giordano et al.   CELL

Plasma membrane—endoplasmic reticulum contact sites regulate phosphatidylcholine synthesis

(2013) Shabnam Tavassoli et al.   EMBO REPORTS

Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

(2013) Kenji Maeda et al.   NATURE

Structure of Osh3 Reveals a Conserved Mode of Phosphoinositide Binding in Oxysterol-Binding Proteins

(2013) Junsen Tong et al.   STRUCTURE

Arv1 Regulates PM and ER Membrane Structure and Homeostasis But is Dispensable for Intracellular Sterol Transport

(2013) Alexander G. Georgiev et al.   TRAFFIC

ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology

(2012) Andrew G. Manford et al.   DEVELOPMENTAL CELL

A Detour for Yeast Oxysterol Binding Proteins

(2012) Christopher T. Beh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A conserved membrane-binding domain targets proteins to organelle contact sites

(2012) A. Toulmay et al.   JOURNAL OF CELL SCIENCE

Regulation of sphingolipid synthesis through Orm1 and Orm2 in yeast

(2012) M. Liu et al.   JOURNAL OF CELL SCIENCE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Yeast Ist2 Recruits the Endoplasmic Reticulum to the Plasma Membrane and Creates a Ribosome-Free Membrane Microcompartment

(2012) Wendelin Wolf et al.   PLoS One

Regulation of Phospholipid Synthesis in the YeastSaccharomyces cerevisiae

(2011) George M. Carman et al.   Annual Review of Biochemistry

Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites

(2011) Christopher J. Stefan et al.   CELL

Comparative Lipidomic Analysis of Mouse and Human Brain with Alzheimer Disease

(2011) Robin B. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A 3D analysis of yeast ER structure reveals how ER domains are organized by membrane curvature

(2011) Matt West et al.   JOURNAL OF CELL BIOLOGY

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

(2011) Maud de Saint-Jean et al.   JOURNAL OF CELL BIOLOGY

Osh Proteins Regulate Membrane Sterol Organization but Are Not Required for Sterol Movement Between the ER and PM

(2011) Alexander G. Georgiev et al.   TRAFFIC

The Sterol-Binding Protein Kes1/Osh4p Is a Regulator of Polarized Exocytosis

(2011) Gabriel Alfaro et al.   TRAFFIC

Structome of Saccharomyces cerevisiae determined by freeze-substitution and serial ultrathin-sectioning electron microscopy

(2011) Masashi Yamaguchi et al.   Microscopy

The role of ABC proteins Aus1p and Pdr11p in the uptake of external sterols in yeast: Dehydroergosterol fluorescence study

(2010) Peter Kohut et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cholesterol, the central lipid of mammalian cells

(2010) Frederick R Maxfield et al.   CURRENT OPINION IN CELL BIOLOGY

Gel Domains in the Plasma Membrane ofSaccharomyces cerevisiae

(2010) Francisco Aresta-Branco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Orm family proteins mediate sphingolipid homeostasis

(2010) David K. Breslow et al.   NATURE

Non-vesicular lipid transport by lipid-transfer proteins and beyond

(2010) Sima Lev   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Modulation of Sphingolipid Metabolism by the Phosphatidylinositol-4-phosphate Phosphatase Sac1p through Regulation of Phosphatidylinositol inSaccharomyces cerevisiae

(2009) Sarah E. Brice et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding of Plasma Membrane Lipids Recruits the Yeast Integral Membrane Protein Ist2 to the Cortical ER

(2009) Marcel André Fischer et al.   TRAFFIC

Regulation of phospholipid synthesis in yeast

(2008) George M. Carman et al.   JOURNAL OF LIPID RESEARCH