Overcoming the Blood–Brain Barrier: Successes and Challenges in Developing Nanoparticle-Mediated Drug Delivery Systems for the Treatment of Brain Tumours
出版年份 2020 全文链接
标题
Overcoming the Blood–Brain Barrier: Successes and Challenges in Developing Nanoparticle-Mediated Drug Delivery Systems for the Treatment of Brain Tumours
作者
关键词
-
出版物
International Journal of Nanomedicine
Volume Volume 15, Issue -, Pages 2999-3022
出版商
Informa UK Limited
发表日期
2020-04-30
DOI
10.2147/ijn.s231479
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- EGFRvIII-CAR-T Cells with PD-1 Knockout Have Improved Anti-Glioma Activity
- (2020) Haifeng Zhu et al. PATHOLOGY & ONCOLOGY RESEARCH
- Lipid Nano- and Microparticles: An Overview of Patent-Related Research
- (2019) Luigi Battaglia et al. Journal of Nanomaterials
- Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution
- (2019) Elisabetta Muntoni et al. Pharmaceutics
- Engineered Mesenchymal Stem Cell/Nanomedicine Spheroid as an Active Drug Delivery Platform for Combinational Glioblastoma Therapy
- (2019) Smruthi Suryaprakash et al. NANO LETTERS
- Drug combination using an injectable nanomedicine hydrogel for glioblastoma treatment
- (2019) Chiara Bastiancich et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Self-assembled angiopep-2 modified lipid-poly (hypoxic radiosensitized polyprodrug) nanoparticles delivery TMZ for glioma synergistic TMZ and RT therapy
- (2019) Zhenkun Zong et al. DRUG DELIVERY
- Current State of Immunotherapy for Treatment of Glioblastoma
- (2019) Tresa McGranahan et al. CURRENT TREATMENT OPTIONS IN ONCOLOGY
- Human Cancer Cell Membrane-Coated Biomimetic Nanoparticles Reduce Fibroblast-Mediated Invasion and Metastasis and Induce T-Cells
- (2019) Jiefu Jin et al. ACS Applied Materials & Interfaces
- Mesenchymal stem cell therapy assisted by nanotechnology: a possible combinational treatment for brain tumor and central nerve regeneration
- (2019) Song Kwon et al. International Journal of Nanomedicine
- Cell-Penetrating Peptide and Transferrin Co-Modified Liposomes for Targeted Therapy of Glioma
- (2019) Xi Wang et al. MOLECULES
- Boosting often overlooked long wavelength emissions of rare-earth nanoparticles for NIR-II fluorescence imaging of orthotopic glioblastoma
- (2019) Zheng Liu et al. BIOMATERIALS
- Cancer Cell Membrane-Coated Nanoparticles for Cancer Management
- (2019) Jenna C. Harris et al. Cancers
- Lactoferrin- and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy
- (2018) Jicai Zhang et al. International Journal of Nanomedicine
- Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival
- (2018) Hernando Lopez-Bertoni et al. NANO LETTERS
- Monitoring the Opening and Recovery of the Blood–Brain Barrier with Noninvasive Molecular Imaging by Biodegradable Ultrasmall Cu2–xSe Nanoparticles
- (2018) Hao Zhang et al. NANO LETTERS
- Artificial apolipoprotein corona enables nanoparticle brain targeting
- (2018) Roberta Dal Magro et al. Nanomedicine-Nanotechnology Biology and Medicine
- CAR T-cell therapy for glioblastoma: recent clinical advances and future challenges
- (2018) Stephen J Bagley et al. NEURO-ONCOLOGY
- Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles
- (2018) Fred C. Lam et al. Nature Communications
- Advances in Glioblastoma Multiforme Treatment: New Models for Nanoparticle Therapy
- (2018) Elif Ozdemir-Kaynak et al. Frontiers in Physiology
- Mesenchymal stem cells loaded with paclitaxel–poly(lactic-co-glycolic acid) nanoparticles for glioma-targeting therapy
- (2018) Xiaoling Wang et al. International Journal of Nanomedicine
- Evaluation of lauroyl-gemcitabine-loaded hydrogel efficacy in glioblastoma rat models
- (2018) Chiara Bastiancich et al. Nanomedicine
- Angiopep-2/IP10-EGFRvIIIscFv modified nanoparticles and CTL synergistically inhibit malignant glioblastoma
- (2018) Xuan Wang et al. Scientific Reports
- Dendritic cell vaccines for high-grade gliomas
- (2018) Matthew Eagles et al. Therapeutics and Clinical Risk Management
- Apolipoprotein E Peptide-Directed Chimeric Polymersomes Mediate an Ultrahigh-Efficiency Targeted Protein Therapy for Glioblastoma
- (2018) Yu Jiang et al. ACS Nano
- Aurora kinase B siRNA-loaded lactoferrin nanoparticles potentiate the efficacy of temozolomide in treating glioblastoma
- (2018) Sonali Kumari et al. Nanomedicine
- MR imaging tracking of inflammation-activatable engineered neutrophils for targeted therapy of surgically treated glioma
- (2018) Meiying Wu et al. Nature Communications
- Angiopep-2-conjugated poly(ethylene glycol)-co-poly(ε-caprolactone) polymersomes for dual-targeting drug delivery to glioma in rats
- (2017) Fei Lu et al. International Journal of Nanomedicine
- Tumortropic adipose-derived stem cells carrying smart nanotherapeutics for targeted delivery and dual-modality therapy of orthotopic glioblastoma
- (2017) Wen-Chia Huang et al. JOURNAL OF CONTROLLED RELEASE
- Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases
- (2017) Christos Tapeinos et al. JOURNAL OF CONTROLLED RELEASE
- Novel model of orthotopic U-87 MG glioblastoma resection in athymic nude mice
- (2017) John Bianco et al. JOURNAL OF NEUROSCIENCE METHODS
- Solid lipid nanoparticles by coacervation loaded with a methotrexate prodrug: preliminary study for glioma treatment
- (2017) Luigi Battaglia et al. Nanomedicine
- Ultrasound for the brain
- (2017) NATURE
- Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence
- (2017) Jingwei Xue et al. Nature Nanotechnology
- Glioma Subclassifications and Their Clinical Significance
- (2017) Ricky Chen et al. Neurotherapeutics
- Tailored theranostic apolipoprotein E3 porphyrin-lipid nanoparticles target glioblastoma
- (2017) M. A. Rajora et al. Chemical Science
- Lipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis
- (2017) Jia-Lin Huang et al. Nature Communications
- Potential New Therapies for Pediatric Diffuse Intrinsic Pontine Glioma
- (2017) Wenyong Long et al. Frontiers in Pharmacology
- Immune Checkpoint in Glioblastoma: Promising and Challenging
- (2017) Jing Huang et al. Frontiers in Pharmacology
- Overcoming blood brain barrier with a dual purpose Temozolomide loaded Lactoferrin nanoparticles for combating glioma (SERP-17-12433)
- (2017) Sonali Kumari et al. Scientific Reports
- Nanostructured lipid carriers, solid lipid nanoparticles, and polymeric nanoparticles: which kind of drug delivery system is better for glioblastoma chemotherapy?
- (2016) Jie Qu et al. DRUG DELIVERY
- Nanocarriers for the treatment of glioblastoma multiforme: Current state-of-the-art
- (2016) Reatul Karim et al. JOURNAL OF CONTROLLED RELEASE
- Lauroyl-gemcitabine-loaded lipid nanocapsule hydrogel for the treatment of glioblastoma
- (2016) C. Bastiancich et al. JOURNAL OF CONTROLLED RELEASE
- Functionalized nanogels carrying an anticancer microRNA for glioblastoma therapy
- (2016) Zohar Shatsberg et al. JOURNAL OF CONTROLLED RELEASE
- Nanoparticle-mediated drug delivery to high-grade gliomas
- (2016) Guido Frosina Nanomedicine-Nanotechnology Biology and Medicine
- Glioma-targeted superparamagnetic iron oxide nanoparticles as drug-carrying vehicles for theranostic effects
- (2016) He-Lin Xu et al. Nanoscale
- Clinical trial of blood-brain barrier disruption by pulsed ultrasound
- (2016) Alexandre Carpentier et al. Science Translational Medicine
- Strategies for transporting nanoparticles across the blood–brain barrier
- (2016) Tian-Tian Zhang et al. Biomaterials Science
- Vincristine and temozolomide combined chemotherapy for the treatment of glioma: a comparison of solid lipid nanoparticles and nanostructured lipid carriers for dual drugs delivery
- (2015) Miaojing Wu et al. DRUG DELIVERY
- Nanostructured lipid carriers based temozolomide and gene co-encapsulated nanomedicine for gliomatosis cerebri combination therapy
- (2015) Zhihua Chen et al. DRUG DELIVERY
- Development of multifunctional lipid nanocapsules for the co-delivery of paclitaxel and CpG-ODN in the treatment of glioblastoma.
- (2015) Giovanna Lollo et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- First in human nanotechnology doxorubicin delivery system to target epidermal growth factor receptors in recurrent glioblastoma
- (2015) James R. Whittle et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Cycling hypoxia induces chemoresistance through the activation of reactive oxygen species-mediated B-cell lymphoma extra-long pathway in glioblastoma multiforme
- (2015) Wei-Ling Chen et al. Journal of Translational Medicine
- Bevacizumab loaded solid lipid nanoparticles prepared by the coacervation technique: preliminary in vitro studies
- (2015) Luigi Battaglia et al. NANOTECHNOLOGY
- Surface-coated PLA nanoparticles loaded with temozolomide for improved brain deposition and potential treatment of gliomas: development, characterization andin vivostudies
- (2014) Darshana Jain et al. DRUG DELIVERY
- Solid lipid nanoparticles as vehicles of drugs to the brain: Current state of the art
- (2014) Lucia Gastaldi et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Nanotherapeutics in the EU: an overview on current state and future directions
- (2014) Ivan Pepic et al. International Journal of Nanomedicine
- Transferrin Receptor-Mediated Endocytosis: A Useful Target for Cancer Therapy
- (2014) Stephanie Tortorella et al. JOURNAL OF MEMBRANE BIOLOGY
- Functional Nanoparticles in Targeting Glioma Diagnosis and Therapies
- (2014) Minghui Li et al. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- Lactoferrin-Modified Poly(ethylene glycol)-Grafted BSA Nanoparticles as a Dual-Targeting Carrier for Treating Brain Gliomas
- (2014) Zhigui Su et al. MOLECULAR PHARMACEUTICS
- Clinical development success rates for investigational drugs
- (2014) Michael Hay et al. NATURE BIOTECHNOLOGY
- Current approaches to the treatment of metastatic brain tumours
- (2014) Taofeek K. Owonikoko et al. Nature Reviews Clinical Oncology
- Low-Grade Gliomas
- (2014) D. A. Forst et al. ONCOLOGIST
- Pharmacokinetics, Brain Delivery, and Efficacy in Brain Tumor-Bearing Mice of Glutathione Pegylated Liposomal Doxorubicin (2B3-101)
- (2014) Pieter J. Gaillard et al. PLoS One
- Cyclic RGD-Linked Polymeric Micelles for Targeted Delivery of Platinum Anticancer Drugs to Glioblastoma through the Blood–Brain Tumor Barrier
- (2013) Yutaka Miura et al. ACS Nano
- Brain targeting effect of camptothecin-loaded solid lipid nanoparticles in rat after intravenous administration
- (2013) Susana M. Martins et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- In Vitro and in Vivo Evaluation of Lactoferrin-Conjugated Liposomes as a Novel Carrier to Improve the Brain Delivery
- (2013) Feng-Yun Huang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Solid lipid nanoparticles carrying chemotherapeutic drug across the blood–brain barrier through insulin receptor-mediated pathway
- (2013) Yung-Chih Kuo et al. JOURNAL OF DRUG TARGETING
- Co-administration of Dual-Targeting Nanoparticles with Penetration Enhancement Peptide for Antiglioblastoma Therapy
- (2013) Deyu Miao et al. MOLECULAR PHARMACEUTICS
- Transport of nanoparticles through the blood–brain barrier for imaging and therapeutic applications
- (2013) Malka Shilo et al. Nanoscale
- Anti-glioma effect and safety of docetaxel-loaded nanoemulsion
- (2012) Huil Gaoe et al. ARCHIVES OF PHARMACAL RESEARCH
- PEG-co-PCL nanoparticles modified with MMP-2/9 activatable low molecular weight protamine for enhanced targeted glioblastoma therapy
- (2012) Guangzhi Gu et al. BIOMATERIALS
- F3 peptide-functionalized PEG-PLA nanoparticles co-administrated with tLyp-1 peptide for anti-glioma drug delivery
- (2012) Quanyin Hu et al. BIOMATERIALS
- Recent advances in brain tumor-targeted nano-drug delivery systems
- (2012) Yu Liu et al. Expert Opinion on Drug Delivery
- Validation of methods for the detection and quantification of engineered nanoparticles in food
- (2012) T.P.J. Linsinger et al. FOOD CHEMISTRY
- Targeted therapy for glioma using cyclic RGD-entrapped polyionic complex nanomicelles
- (2012) Liu et al. International Journal of Nanomedicine
- Glioblastoma Treatment: Bypassing the Toxicity of Platinum Compounds by Using Liposomal Formulation and Increasing Treatment Efficiency With Concomitant Radiotherapy
- (2012) Gabriel Charest et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Increased brain uptake of docetaxel and ketoconazole loaded folate-grafted solid lipid nanoparticles
- (2012) Vinay Kumar Venishetty et al. Nanomedicine-Nanotechnology Biology and Medicine
- β-Hydroxybutyric acid grafted solid lipid nanoparticles: A novel strategy to improve drug delivery to brain
- (2012) Vinay Kumar Venishetty et al. Nanomedicine-Nanotechnology Biology and Medicine
- The big picture on nanomedicine: the state of investigational and approved nanomedicine products
- (2012) Michael L. Etheridge et al. Nanomedicine-Nanotechnology Biology and Medicine
- Silver nanocrystals sensitize magnetic-nanoparticle-mediated thermo-induced killing of cancer cells
- (2011) L. Liu et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- In Vivo Specific Delivery of c-Met siRNA to Glioblastoma Using Cationic Solid Lipid Nanoparticles
- (2011) Juyoun Jin et al. BIOCONJUGATE CHEMISTRY
- Dual targeting effect of Angiopep-2-modified, DNA-loaded nanoparticles for glioma
- (2011) Shixian Huang et al. BIOMATERIALS
- Fluorescence and image guided resection in high grade glioma
- (2011) Pier Paolo Panciani et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- Lactoferrin modified doxorubicin-loaded procationic liposomes for the treatment of gliomas
- (2011) Huali Chen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles
- (2011) Xiao-ning Lin et al. International Journal of Nanomedicine
- In vitro and in vivo efficacy of edelfosine-loaded lipid nanoparticles against glioma
- (2011) Ander Estella-Hermoso de Mendoza et al. JOURNAL OF CONTROLLED RELEASE
- Chloride channel-mediated brain glioma targeting of chlorotoxin-modified doxorubicine-loaded liposomes
- (2011) Yu Xiang et al. JOURNAL OF CONTROLLED RELEASE
- A phase I/II trial of enzastaurin in patients with recurrent high-grade gliomas
- (2011) Teri N. Kreisl et al. NEURO-ONCOLOGY
- The therapeutic efficacy of conjugated linoleic acid – Paclitaxel on glioma in the rat
- (2010) Xi-Yu Ke et al. BIOMATERIALS
- A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α
- (2010) Sascha Seidel et al. BRAIN
- The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
- (2010) John M. Heddleston et al. CELL CYCLE
- Lactoferrin-Conjugated Biodegradable Polymersome Holding Doxorubicin and Tetrandrine for Chemotherapy of Glioma Rats
- (2010) Zhiqing Pang et al. MOLECULAR PHARMACEUTICS
- mTOR signaling and drug development in cancer
- (2010) Janet Dancey Nature Reviews Clinical Oncology
- Experimental approaches for the treatment of malignant gliomas
- (2010) Leopold Arko et al. PHARMACOLOGY & THERAPEUTICS
- Stratified phase II trial of cetuximab in patients with recurrent high-grade glioma
- (2009) B. Neyns et al. ANNALS OF ONCOLOGY
- Antitumor effects of polysorbate-80 coated gemcitabine polybutylcyanoacrylate nanoparticles in vitro and its pharmacodynamics in vivo on C6 glioma cells of a brain tumor model
- (2009) Chun-Xia Wang et al. BRAIN RESEARCH
- Dose-response assessment of tariquidar and elacridar and regional quantification of P-glycoprotein inhibition at the rat blood-brain barrier using (R)-[11C]verapamil PET
- (2009) Claudia Kuntner et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Cediranib: profile of a novel anti-angiogenic agent in patients with glioblastoma
- (2009) Jörg Dietrich et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Edema Control by Cediranib, a Vascular Endothelial Growth Factor Receptor–Targeted Kinase Inhibitor, Prolongs Survival Despite Persistent Brain Tumor Growth in Mice
- (2009) Walid S. Kamoun et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy
- (2009) RuiRong Yuan et al. Journal of Hematology & Oncology
- Imatinib in combination with hydroxyurea versus hydroxyurea alone as oral therapy in patients with progressive pretreated glioblastoma resistant to standard dose temozolomide
- (2009) Gregor Dresemann et al. JOURNAL OF NEURO-ONCOLOGY
- Unknown
- (2009) Andreas Argyriou et al. MOLECULAR MEDICINE
- Antitumor activity of cetuximab against malignant glioma cells overexpressing EGFR deletion mutant variant III
- (2008) Junya Fukai et al. CANCER SCIENCE
- Randomized Phase II Study of Cilengitide, an Integrin-Targeting Arginine-Glycine-Aspartic Acid Peptide, in Recurrent Glioblastoma Multiforme
- (2008) David A. Reardon et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
- (2008) Michael D. Prados et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Trial of Single-Agent Bevacizumab Followed by Bevacizumab Plus Irinotecan at Tumor Progression in Recurrent Glioblastoma
- (2008) Teri N. Kreisl et al. JOURNAL OF CLINICAL ONCOLOGY
- Bevacizumab for recurrent malignant gliomas: Efficacy, toxicity, and patterns of recurrence
- (2008) A. D. Norden et al. NEUROLOGY
- Modulation of P-Glycoprotein at the Blood-Brain Barrier: Opportunities to Improve Central Nervous System Pharmacotherapy
- (2008) D. S. Miller et al. PHARMACOLOGICAL REVIEWS
- Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma
- (2008) Tim F Cloughesy et al. PLOS MEDICINE
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